PIPA5110244
PTS Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5110244-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5110244 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
PTS
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Pts
Gene Alias
6-pyruvoyl tetrahydrobiopterin synthase; 6-pyruvoyltetrahydropterin synthase; 6-pyruvoyl-tetrahydropterin synthase; PTP synthase; PTPS; PTS
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19286, 29498, 5805
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.95 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P27213, Q03393, Q9R1Z7
Gene Symbols
Pts
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human PTS (NP_000308.1).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MSTEGGGRRC QAQVSRRISF SASHRLYSKF LSDEENLKLF GKCNNPNGHG HNYKVVVTVH GEIDPATGMV MNLADLKKYM EEAIMQPLDH KNLDMDVPYF ADVVSTTENV AVYIWDNLQK VLPVGVLYKV KVYETDNNIV VYKGE The tetrahydrobiopterin (BH4) cofactor is essential for hepatic hydroxylase, which is involved in phenylalanine degradation and catecholamine and serotonin biosynthesis
- BH4 is also an essential and limiting cofactor for all types of nitric oxide synthase
- BH4 deficiency results in hyperphenylalaninemia and monoamine neurotransmitter depletion and is most commonly due to autosomal recessive mutation in 6-pyruvoyltetrahydropterin synthase (PTPS), the second enzyme for BH4 biosynthesis
- The active site of PTPS consists of the pterin-anchoring Glu A107 neighbored by two catalytic motifs: a Zn(II) binding site and an inter-subunit catalytic triad formed by Cys A42, Asp B88 and His B89
- The active site of PTPS undergoes a Zn and Mg-dependent reaction that includes a triphosphate elimination, a stereospecific reduction and the oxidation of both side hydroxyl groups
- The catalytic triad of PTPS is involved in the deprotonation of the side-chain carbons of substrates
- In addition, Ser 19 of human PTPS may be a substrate for cGMP-dependent protein kinase type II phosphorylation in vivo, which is essential for normal activity of PTPS.
Compare Similar Items
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Antigen: PTS
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Pts
Gene Alias: 6-pyruvoyl tetrahydrobiopterin synthase; 6-pyruvoyltetrahydropterin synthase; 6-pyruvoyl-tetrahydropterin synthase; PTP synthase; PTPS; PTS
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19286, 29498, 5805
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.95 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P27213, Q03393, Q9R1Z7
Gene Symbols: Pts
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human PTS (NP_000308.1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PTS
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Pts
Gene Alias:
6-pyruvoyl tetrahydrobiopterin synthase; 6-pyruvoyltetrahydropterin synthase; 6-pyruvoyl-tetrahydropterin synthase; PTP synthase; PTPS; PTS
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19286, 29498, 5805
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.95 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P27213, Q03393, Q9R1Z7
Gene Symbols:
Pts
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human PTS (NP_000308.1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PURB
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PURB
Gene Alias: 2310015K15Rik; AA114818; Cager-2; D11Bwg0414e; LOW QUALITY PROTEIN: transcriptional activator protein Pur-beta; purb; PurB beta; purb protein; purbb; PURBETA; pur-beta; purine rich element binding protein B; purine-rich element binding protein B; purine-rich element binding protein Bb; purine-rich element-binding protein B; purine-rich single-stranded DNA-binding protein beta; transcription factor Pur-beta; transcriptional activator protein Pur-beta; Vascular actin single-stranded DNA-binding factor 2 p44 component; zgc:65916
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5814
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.59 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: Q96QR8
Gene Symbols: PURB
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 213-312 of human PURB (NP_1500931)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PURB
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PURB
Gene Alias:
2310015K15Rik; AA114818; Cager-2; D11Bwg0414e; LOW QUALITY PROTEIN: transcriptional activator protein Pur-beta; purb; PurB beta; purb protein; purbb; PURBETA; pur-beta; purine rich element binding protein B; purine-rich element binding protein B; purine-rich element binding protein Bb; purine-rich element-binding protein B; purine-rich single-stranded DNA-binding protein beta; transcription factor Pur-beta; transcriptional activator protein Pur-beta; Vascular actin single-stranded DNA-binding factor 2 p44 component; zgc:65916
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5814
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.59 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
Q96QR8
Gene Symbols:
PURB
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 213-312 of human PURB (NP_1500931)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Nectin 4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NECTIN4
Gene Alias: 1200017F15Rik; EDSS1; ig superfamily receptor LNIR; LNIR; nectin 4; nectin cell adhesion molecule 4; NECTIN4; Nectin-4; poliovirus receptor-related 4; poliovirus receptor-related protein 4; Processed poliovirus receptor-related protein 4; PRR4; Pvrl4; RGD1559826
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 498281, 71740, 81607
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 3.1 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: Q8R007, Q96NY8
Gene Symbols: NECTIN4
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 32-146 of human PVRL4 (NP_1121782)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Nectin 4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NECTIN4
Gene Alias:
1200017F15Rik; EDSS1; ig superfamily receptor LNIR; LNIR; nectin 4; nectin cell adhesion molecule 4; NECTIN4; Nectin-4; poliovirus receptor-related 4; poliovirus receptor-related protein 4; Processed poliovirus receptor-related protein 4; PRR4; Pvrl4; RGD1559826
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
498281, 71740, 81607
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
3.1 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
Q8R007, Q96NY8
Gene Symbols:
NECTIN4
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 32-146 of human PVRL4 (NP_1121782)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PYGL
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PYGL
Gene Alias: glycogen liver; Glycogen phosphorylase, liver form; GPLL; GSD6; Lgp; liver glycogen phosphorylase; phosphorylase, glycogen, liver; PYGL
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 110095, 5836, 64035
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.425 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: P06737, P09811, Q9ET01
Gene Symbols: PYGL
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 690-847 of human PYGL (NP_0028543)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PYGL
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PYGL
Gene Alias:
glycogen liver; Glycogen phosphorylase, liver form; GPLL; GSD6; Lgp; liver glycogen phosphorylase; phosphorylase, glycogen, liver; PYGL
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
110095, 5836, 64035
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.425 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
P06737, P09811, Q9ET01
Gene Symbols:
PYGL
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 690-847 of human PYGL (NP_0028543)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG