PIPA5110297

RIG-I Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5110297-Each-of-1 In Stock ₹ 44,705.10

PIPA5110297 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

RIG-I

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DDX58

Gene Alias

6430573D20Rik; C330021E21; Ddx58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; DEAD/H box polypeptide RIG-I; DEAD-box protein 58; DEXD/H-box helicase 58; probable ATP-dependent RNA helicase DDX58; Retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; RIG-1; RIGI; RIG-I; RIG-I-like receptor 1; RLR-1; RNA helicase RIG-I; SGMRT2

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23586

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

3.47 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

O95786

Gene Symbols

DDX58

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 825-925 of human Rig-I/DDX58 (NP_0551292)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5109636

--

Img

Thermo Scientific

PIPA5109628

--

Img

Thermo Scientific

PIPA5109625

--

Img

Thermo Scientific

PIPA5109627

--

Img

Thermo Scientific

PIPA5109635

--

Img

Thermo Scientific

PIPA5109580

--

Img

Thermo Scientific

PIPA5110302

--

Img

Thermo Scientific

PIPA5110213

--

Description

  • Immunogen sequence: VIEECHYTVL GDAFKECFVS RPHPKPKQFS SFEKRAKIFC ARQNCSHDWG IHVKYKTFEI PVIKIESFVV EDIATGVQTL YSKWKDFHFE KIPFDPAEMS K Retinoic acid-inducible gene I, RIG-I is a pattern recognition receptor (PRR) involved in the recognition of viral dsRNA
  • Along with MDA5, RIG-I detects viral dsRNA and activates the innate immune response
  • Both MDA5 and RIG-I are RNA helicases and they perform overlapping as well as distinct roles
  • RIG-I is activated by dsRNAs without a 5'-triphosphate end and short dsRNAs, whereas MDA5 is activated by long dsRNAs
  • Once activated, both proteins signal through IPS-1 activating transcription factors NF-kappaB and IRF-3 (1) and μgtimately activating apoptosis, cytokine signaling, and inflammation
  • RIG-I is essential for signaling by influenza A, influenza B, human respiratory syncytial virus (3), paromyxoviruses, Japanese encephalitis virus, and West Nile virus
  • MicroRNA-146a has been implicated in feedback inhibition of RIG-I-dependant antiviral response by negatively regulating RIG-I targets TRAF6, IRAK1, and IRAK2
  • Recent evidence has implicated RIG-I in the detection of cytosolic DNA through RNA polymerase III activity.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5110297

--


Antigen:
RIG-I

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DDX58

Gene Alias:
6430573D20Rik; C330021E21; Ddx58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; DEAD/H box polypeptide RIG-I; DEAD-box protein 58; DEXD/H-box helicase 58; probable ATP-dependent RNA helicase DDX58; Retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; RIG-1; RIGI; RIG-I; RIG-I-like receptor 1; RLR-1; RNA helicase RIG-I; SGMRT2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23586

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
3.47 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O95786

Gene Symbols:
DDX58

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 825-925 of human Rig-I/DDX58 (NP_0551292)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5110298

--


Antigen:
RIN1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RIN1

Gene Alias:
Ras and Rab interactor 1; ras inhibitor; ras inhibitor 1; ras inhibitor JC99; ras inhibitor RIN1; ras interaction/interference protein 1; RIBA; Rin1; RIT2; ROC2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
207119, 225870

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.7 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P97680, Q921Q7

Gene Symbols:
RIN1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human RIN1 (NP_004283.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5110299

--


Antigen:
RIN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RIN2

Gene Alias:
2010003K16Rik; 4632403N06Rik; AW821980; MACS; RAB5 interacting protein 2; ras and Rab interactor 2; RAS association (RalGDS/AF-6) domain containing protein JC265; RAS association domain family 4; Ras inhibitor JC265; ras interaction/interference protein 2; RASSF4; Rin2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54453, 74030

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.03 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
Q8WYP3, Q9D684

Gene Symbols:
RIN2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 596-895 of human RIN2 (NP_061866.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5110300

--


Antigen:
RMI1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RMI1

Gene Alias:
4932432N11Rik; BLAP75; BLM-associated polypeptide, 75 kDa; BLM-associated protein 75 kDa; BLM-associated protein of 75 kDa; C79893; C9orf76; FAAP75; FLJ12888; homolog of yeast RecQ-mediated genome instability 1 (RMI1); RecQ mediated genome instability 1; recQ-mediated genome instability protein 1; recQ-mediated genome instability protein-like protein; RGD1310671; RMI1; RMI1, RecQ mediated genome instability 1, homolog; RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae); RP11-346I8.1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
74386, 80010

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.55 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9D4G9, Q9H9A7

Gene Symbols:
RMI1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human RMI1 (NP_079221.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG