PIPA5110430

SRPK2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5110430-Each-of-1 In Stock ₹ 44,705.10

PIPA5110430 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SRPK2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SRPK2

Gene Alias

AW226533; AW492537; AW547358; H_RG152G17.1a; H_RG152G17.1b; mSRPK2; serine kinase SRPK2; serine/arginine-rich protein specific kinase 2; serine/arginine-rich protein-specific kinase 2; serine/arginine-rich splicing factor kinase 2; serine/threonine-protein kinase SRPK2; SFRS protein kinase 2; SFRSK2; SR protein kinase 2; SRPK2; SR-protein-specific kinase 2; SRSF protein kinase 2; SRSF protein kinase 2 C-terminal; SRSF protein kinase 2 N-terminal; Wbp6; WUGSC:H_RG152G17.1a; WW domain binding protein 6

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20817, 296753, 6733

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.06 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

O54781, P78362

Gene Symbols

SRPK2

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 420-520 of human SRPK2 (NP_872633.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: NAESDYTYSS SYEQFNGELP NGRHKIPESQ FPEFSTSLFS GSLEPVACGS VLSEGSPLTE QEESSPSHDR SRTVSASSTG DLPKAKTRAA DLLVNPLDPR N SRPK2, along with SRPK1, is most likely the cellular protein kinase mediating HBV core protein phosphorylation during viral infection
  • It therefore represents an important host cell target for therapeutic intervention in HBV infection
  • Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression
  • This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression
  • Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up-regulation
  • Plays an essential role in spliceosomal B complex formation via the phosphorylation of DDX23/PRP28
  • Plays a negative role in the regulation of HBV replication through a mechanism not involving the phosphorylation of the core protein but by reducing the packaging efficiency of the pregenomic RNA (pgRNA) without affecting the formation of the viral core particles .

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Img

Thermo Scientific

PIPA5110430

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Antigen:
SRPK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SRPK2

Gene Alias:
AW226533; AW492537; AW547358; H_RG152G17.1a; H_RG152G17.1b; mSRPK2; serine kinase SRPK2; serine/arginine-rich protein specific kinase 2; serine/arginine-rich protein-specific kinase 2; serine/arginine-rich splicing factor kinase 2; serine/threonine-protein kinase SRPK2; SFRS protein kinase 2; SFRSK2; SR protein kinase 2; SRPK2; SR-protein-specific kinase 2; SRSF protein kinase 2; SRSF protein kinase 2 C-terminal; SRSF protein kinase 2 N-terminal; Wbp6; WUGSC:H_RG152G17.1a; WW domain binding protein 6

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20817, 296753, 6733

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.06 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O54781, P78362

Gene Symbols:
SRPK2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 420-520 of human SRPK2 (NP_872633.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5110431

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Antigen:
SRSF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SRSF1

Gene Alias:
1110054N12Rik; 5730507C05Rik; 6330415C05Rik; AI482334; Alternative-splicing factor 1; ASF; ASF/SF2; ASF-1; AW491331; OK/SW-cl.3; pre-mRNA-splicing factor SF2, P33 subunit; pre-mRNA-splicing factor SRp30a; serine and arginine rich splicing factor 1; serine/arginine-rich splicing factor 1; SF2; SF2p33; SFRS1; splicing factor 2; splicing factor, arginine/serine-rich 1; splicing factor, arginine/serine-rich 1 (ASF/SF2); splicing factor, arginine/serine-rich 1B; splicing factor, arginine/serine-rich, 30-KD, A; SR splicing factor 1; SRp30a; Srsf1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
110809, 6426, 689890

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.06 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.:
Q07955, Q6PDM2

Gene Symbols:
SRSF1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-248 of human SRSF1/SF2/ASF (NP_0088551)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5110432

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Antigen:
SSFA2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ITPRID2

Gene Alias:
5730488C15Rik; cleavage signal-1 protein; CS1; CS-1; ITPRID2; ITPR-interacting domain-containing protein 2; KIAA1927; Ki-ras-induced actin-interacting protein; Krap; KRAS-induced actin-interacting protein; mKIAA1927; Protein ITPRID2; SPAG13; sperm associated antigen 13; sperm specific antigen 2; sperm-specific antigen 2; Sperm-specific antigen 2 homolog; SSFA2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
70599

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.83 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
Q922B9

Gene Symbols:
ITPRID2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1259 of human SSFA2 (NP_001123917.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5110433

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Antigen:
SSH2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SSH2

Gene Alias:
hSSH-2L; KIAA1725; mSSH-2L; Protein phosphatase Slingshot homolog 2; slingshot 2L; slingshot homolog 2; slingshot homolog 2 (Drosophila); slingshot protein phosphatase 2; slingshot-like 2; Ssh2; SSH-2; Ssh2l; SSH-2L; SSH-like protein 2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
237860, 303342, 85464

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.55 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q5SW75, Q76I76

Gene Symbols:
SSH2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 53-202 of human SSH2 (NP_2037472)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG