PIPA5110484

THEM4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5110484-Each-of-1 In Stock ₹ 44,705.10

PIPA5110484 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

THEM4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

THEM4

Gene Alias

2700077M13Rik; 4921507I02Rik; Acyl-CoA thioesterase THEM4; acyl-coenzyme A thioesterase THEM4; carboxyl-terminal modulator protein; C-terminal modulator protein; CTMP; RGD1304723; THEM4; Thioesterase superfamily member 4

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

117145, 75778

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

2.27 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

Q3UUI3, Q5T1C6

Gene Symbols

THEM4

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 37-150 of human THEM4 (NP_444283.2).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: SSEEVILKDC SVPNPSWNKD LRLLFDQFMK KCEDGSWKRL PSYKRTPTEW IQDFKTHFLD PKLMKEEQMS QAQLFTRSFD DGLGFEYVMF YNDIEKRMVC LFQGGPYLEG PPGF THEM4, also known as CTMP, binds specifically to the carboxy-terminal regulatory domain of PKB/Akt at the plasma membrane and acts as a negative regulator, reversing the phenotype of v-Akt-transformed cells
  • Hypermethylation of the THEM4 promoter and transcriptional downregulation of the gene has been reported in multiple glioblastomas, suggesting that epigenetic regulation of THEM4 may play a role in the progression of this cancer
  • Bioinformatic analysis, confirmed by in vitro testing, indicates that THEM4 is a broad-range, high activity acyl-CoA thioesterase
  • Recent reports have also indicated that TMEM4 is a mitochondrial protein whose overexpression is associated with an increase in mitochondrial membrane depolarization and caspase-3 and PARP cleavage, suggesting that THEM4 is involved in the apoptotic program.

Compare Similar Items

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Img

Thermo Scientific

PIPA5110484

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Antigen:
THEM4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
THEM4

Gene Alias:
2700077M13Rik; 4921507I02Rik; Acyl-CoA thioesterase THEM4; acyl-coenzyme A thioesterase THEM4; carboxyl-terminal modulator protein; C-terminal modulator protein; CTMP; RGD1304723; THEM4; Thioesterase superfamily member 4

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
117145, 75778

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
2.27 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
Q3UUI3, Q5T1C6

Gene Symbols:
THEM4

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 37-150 of human THEM4 (NP_444283.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5110485

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Antigen:
THOC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
THOC2

Gene Alias:
6330441O12Rik; CXorf3; D130005M13Rik; dJ506G2.1; Gm1139; Gm1793; hTREX120; mental retardation, X-linked 12; mental retardation, X-linked 35; MRX12; MRX35; RGD1561623; THO complex 2; THO complex subunit 2; Tho2; THOC2; transcription/export complex subunit 2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
331401, 57187

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
B1AZI6, Q8NI27

Gene Symbols:
THOC2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human THOC2 (NP_0010750191)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5110486

--


Antigen:
THOC3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
THOC3

Gene Alias:
2410044K02Rik; AL033344; hTREX45; LOC529231 protein; TEX1; TEX1 homolog; THO complex 3; THO complex subunit 3; Tho3; Thoc3; zgc:100815

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
73666, 84321

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.1 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
Q8VE80, Q96J01

Gene Symbols:
THOC3

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human THOC3 (NP_115737.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5110487

--


Antigen:
TIA-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TIA1

Gene Alias:
2310050N03Rik; AI256674; cytotoxic granule-associated RNA binding protein 1; cytotoxic granule-associated RNA-binding protein 1; mTIA-1; Nucleolysin TIA-1; nucleolysin TIA-1 isoform p40; p40 TIA 1; p40-TIA-1; p40-TIA-1 (containing p15-TIA-1); RNA-binding protein TIA-1; T-cell-restricted intracellular antigen-1; Tia; TIA 1; TIA1; TIA-1; TIA1 cytotoxic granule-associated RNA binding protein; TIA1 protein; TIAL1; TIAR; WDM

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21841, 7072

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.59 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P31483, P52912

Gene Symbols:
TIA1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 287-386 of human TIA1 (NP_0715052)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG