PIPA5110587

YTHDF1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5110587-Each-of-1 In Stock ₹ 44,191.74

PIPA5110587 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

YTHDF1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

YTHDF1

Gene Alias

2210410K23Rik; 8030473O16; C20orf21; DACA-1; DACA-1 homolog; Dermatomyositis associated with cancer putative autoantigen 1; dermatomyositis associated with cancer putative autoantigen 1 homolog; fb49c02; wu:fb49c02; wu:fi19h06; wu:fj87f09; wu:fp06c11; YTH domain family 1; YTH domain family protein 1; YTH domain family, member 1; YTH domain-containing family protein 1; YTH N(6)-methyladenosine RNA binding protein 1; YTH N6-methyladenosine RNA binding protein 1; Ythdf1; zgc:55657

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

228994, 296467, 54915

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.68 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

P59326, Q9BYJ9

Gene Symbols

YTHDF1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 280-390 of human YTHDF1 (NP_0602682)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: VPKAPVPQQA PSPQAAPQPQ QVAQPLPAQP PALAQPQYQS PQQPPQTRWV APRNRNAAFG QSGGAGSDSN SPGNVQPNSA PSVESHPVLE KLKAAHSYNP KEFEWNLKSG R Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency (PubMed:24284625, PubMed:26046440, PubMed:26318451)
  • M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:24284625)
  • Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation (PubMed:26046440)
  • Required to facilitate learning and memory formation in the hippocampus by enhancing protein synthesis upon neuronal stimulation: in response to neuronal stimulation, binds to m6A-containing neuronal mRNAs, promoting their translation, thereby contributing to learning and memory
  • Acts as a regulator of axon guidance by binding to m6A-containing ROBO3 transcripts, thereby promoting their translation
  • Acts as a negative regulator of antigen cross-presentation in myeloid dendritic cells
  • Acts by binding and promoting translation of m6A-containing transcripts encoding proteins involved in lysosomal degradation and phagosome maturation, leading to increased antigen degradation in myeloid dendritic cells
  • In the context of tumorigenesis, negative regulation of antigen cross-presentation limits the anti-tumor response by reducing efficiency of tumor-antigen cross-presentation
  • [UniProt]

Compare Similar Items

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Img

Thermo Scientific

PIPA5110587

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Antigen:
YTHDF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
YTHDF1

Gene Alias:
2210410K23Rik; 8030473O16; C20orf21; DACA-1; DACA-1 homolog; Dermatomyositis associated with cancer putative autoantigen 1; dermatomyositis associated with cancer putative autoantigen 1 homolog; fb49c02; wu:fb49c02; wu:fi19h06; wu:fj87f09; wu:fp06c11; YTH domain family 1; YTH domain family protein 1; YTH domain family, member 1; YTH domain-containing family protein 1; YTH N(6)-methyladenosine RNA binding protein 1; YTH N6-methyladenosine RNA binding protein 1; Ythdf1; zgc:55657

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
228994, 296467, 54915

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.68 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P59326, Q9BYJ9

Gene Symbols:
YTHDF1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 280-390 of human YTHDF1 (NP_0602682)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5110590

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Antigen:
ZC3H12D

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZC3H12D

Gene Alias:
C6orf95; D730019B10Rik; dJ281H8.1; MCP-induced protein 4; MCPIP4; p34; probable ribonuclease ZC3H12D; RP1-281H8.5; Tfl; Transformed follicular lymphoma; transformed follicular lymphoma homolog; tumor suppressor TFL; zc3h12d; Zinc finger CCCH domain-containing protein 12D; zinc finger CCCH type containing 12D; zinc finger CCCH-type containing 12D

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
237256, 308266, 340152

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.14 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
A2A288, Q8BIY3

Gene Symbols:
ZC3H12D

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 150-230 of human ZC3H12D (NP_997243.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5110591

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Antigen:
ZDHHC8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Zdhhc8

Gene Alias:
D16H22S1738E; DHHC8; DHHC-8; DHHC-containing protein 8; E330009O14Rik; KIAA1292; membrane-associated DHHC8 zinc finger protein; Op53c05; Probable palmitoyltransferase ZDHHC8; ZDHHC8; ZDHHCL1; zinc finger DHHC domain-containing protein 8; zinc finger DHHC-type containing 8; zinc finger protein 378; zinc finger, DHHC domain containing 8; zinc finger, DHHC domain like containing 1; zinc finger, DHHC-type containing 8; zinc finger, DHHC-type containing 8-like; ZNF378

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27801, 29801

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.36 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
Q5Y5T5, Q9ULC8

Gene Symbols:
Zdhhc8

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human ZDHHC8 (NP_037505.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5110592

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Antigen:
ZDHHC9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZDHHC9

Gene Alias:
6430508G22; 9530098M12Rik; antigen MMSA-1; Asp-His-His-Cys domain containing protein 9; CGI89; CGI-89; CXorf11; DHHC9; DHHC-9; membrane-associated DHHC9 zinc finger protein; MMSA1; MRXSZ; Palmitoyltransferase ZDHHC9; UNQ261/PRO298; ZDHHC10; ZDHHC9; Zinc finger DHHC domain-containing protein 9; zinc finger DHHC-type containing 9; zinc finger protein 379; Zinc finger protein 380; zinc finger, DHHC domain containing 10; zinc finger, DHHC domain containing 9; zinc finger, DHHC-type containing 9; ZNF379; ZNF380

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
208884, 302808, 51114

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.13 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P59268, Q9Y397

Gene Symbols:
ZDHHC9

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 250-364 of human ZDHHC9 (NP_057116.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG