PIPA5110688

USP13 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5110688-Each-of-1 In Stock ₹ 47,015.22

PIPA5110688 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

USP13

Classification

Polyclonal

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q92995

Gene Symbols

USP13

Immunogen

Recombinant Protein corresonding to Human USP13

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry

Conjugate

Unconjugated

Gene

USP13

Gene Alias

2700071E21Rik; AI848077; Deubiquitinating enzyme 13; Isopeptidase T-3; ISOT3; IsoT-3; Ubiquitin carboxyl-terminal hydrolase 13; ubiquitin specific peptidase 13; ubiquitin specific peptidase 13 (isopeptidase T-3); ubiquitin specific protease 13 (isopeptidase T-3); Ubiquitin thioesterase 13; ubiquitin thiolesterase 13; ubiquitin-specific-processing protease 13; usp13; wu:fc61g08

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8975

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • Immunogen sequence: RKAVYFTGNM GAEVAFNWII VHMEEPDFAE PLTMPGYGGA ASAGASVFGA SGLDNQPPEE IVAIITSMGF QRNQAIQALR ATNNNLERAL DWIFSHPEFE EDSDFVIEME NNANANIISE AKPEGPRVKD GSGTYELFAF ISH Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2 and USP10 and is involved in various processes such as autophagy and endoplasmic reticulum-associated degradation (ERAD)
  • Component of a regulatory loop that controls autophagy and p53/TP53 levels: mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes
  • Also deubiquitinates USP10, an essential regulator of p53/TP53 stability
  • In turn, PIK3C3/VPS34-containing complexes regulate USP13 stability, suggesting the existence of a regulatory system by which PIK3C3/VPS34-containing complexes regulate p53/TP53 protein levels via USP10 and USP13
  • Recruited by nuclear UFD1 and mediates deubiquitination of SKP2, thereby regulating endoplasmic reticulum-associated degradation (ERAD)
  • Also regulates ERAD through the deubiquitination of UBL4A a component of the BAG6/BAT3 complex
  • Mediates stabilization of SIAH2 independently of deubiquitinase activity: binds ubiquitinated SIAH2 and acts by impairing SIAH2 autoubiquitination
  • Has a weak deubiquitinase activity in vitro and preferentially cleaves 'Lys-63'-linked polyubiquitin chains
  • In contrast to USP5, it is not able to mediate unanchored polyubiquitin disassembly
  • Able to cleave ISG15 in vitro; however, additional experiments are required to confirm such data
  • [UniProt]

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Img

Thermo Scientific

PIPA5110688

--


Antigen:
USP13

Classification:
Polyclonal

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q92995

Gene Symbols:
USP13

Immunogen:
Recombinant Protein corresonding to Human USP13

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry

Conjugate:
Unconjugated

Gene:
USP13

Gene Alias:
2700071E21Rik; AI848077; Deubiquitinating enzyme 13; Isopeptidase T-3; ISOT3; IsoT-3; Ubiquitin carboxyl-terminal hydrolase 13; ubiquitin specific peptidase 13; ubiquitin specific peptidase 13 (isopeptidase T-3); ubiquitin specific protease 13 (isopeptidase T-3); Ubiquitin thioesterase 13; ubiquitin thiolesterase 13; ubiquitin-specific-processing protease 13; usp13; wu:fc61g08

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8975

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA5110689

--


Antigen:
MATK

Classification:
Polyclonal

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P42679

Gene Symbols:
MATK

Immunogen:
Recombinant Protein corresonding to Human MATK

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
MATK

Gene Alias:
Batk; CHK; Csk homologous kinase; Csk-homologous kinase; Csk-type protein tyrosine kinase; CTK; DKFZp434N1212; Hematopoietic consensus tyrosine-lacking kinase; HHYLTK; hydroxyaryl-protein kinase; HYL; HYL tyrosine kinase; HYLTK; leukocyte carboxyl-terminal src kinase related; Lsk; Matk; megakaryocyte-associated tyrosine kinase; megakaryocyte-associated tyrosine kinase (non-receptor protein tyrosine kinase); megakaryocyte-associated tyrosine-protein kinase; MGC1708; MGC2101; non-receptor protein kinase protein; Ntk; Protein kinase BATK; protein kinase HYL; Protein kinase NTK; tyrosine kinase MATK; tyrosine-protein kinase CTK; tyrosylprotein kinase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4145

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA5110691

--


Antigen:
AATF

Classification:
Polyclonal

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9NY61

Gene Symbols:
Aatf

Immunogen:
Recombinant Protein corresonding to Human AATF

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Gene:
Aatf

Gene Alias:
4933415H02Rik; 5830465M17Rik; Aatf; apoptosis antagonizing transcription factor; apoptosis-antagonizing transcription factor; BFR2; CHE1; CHE-1; DED; HSPC277; Protein AATF; rb-binding protein Che-1; Traube protein; Trb

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26574

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA5110692

--


Antigen:
Renin

Classification:
Polyclonal

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P00797

Gene Symbols:
Ren

Immunogen:
Recombinant Protein corresonding to Human Renin

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Gene:
Ren

Gene Alias:
angiotensin-forming enzyme; angiotensinogenase; aspartyl-protease; D19352; EC 3.4.23; EC 3.4.23.15; FLJ10761; HNFJ2; kidney renin; RATRENAA; Ren; Ren1; Ren-1; Ren1c; Ren1d; Ren-A; RENAA; Renin; renin 1 structural; renin b; renin precursor, renal; renin-1; Rn-1; Rnr

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5972

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid