PIPA5110866

RNF216 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5110866-Each-of-1 In Stock ₹ 47,015.22

PIPA5110866 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

RNF216

Classification

Polyclonal

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9NWF9

Gene Symbols

RNF216

Immunogen

Recombinant Protein corresonding to Human RNF216

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry

Conjugate

Unconjugated

Gene

RNF216

Gene Alias

2810055G22Rik; AI647468; AU019462; C86502; CAHH; E3 ubiquitin ligase; E3 ubiquitin-protein ligase RNF216; F830018F18Rik; RGD1565135; RING finger protein 216; RING-type E3 ubiquitin transferase RNF216; RNF216; Triad domain-containing protein 3; TRIAD3; triad3a; U7I1; UBCE7IP1; UbcM4-interacting protein 83; ubiquitin-conjugating enzyme 7-interacting protein 1; Uip83; Zin; zinc finger protein inhibiting NF-kappa-B

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

54476

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Immunogen sequence: KVIILEEGSL LYTESDPLET QNQSSEDSET ELLSNLGESA ALADDQAIEE DCWLDHPYFQ SLNQQPREIT NQVVPQERQP EAELGRLLFQ HEFPGPAFP Activation of NF-κB as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses
  • Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88
  • Several regulatory mechanisms exist to control TLR signal transduction, including the inhibition of TLR expression and signaling by molecules such as ST2 and SIGIRR
  • Another mechanism is by the ubi-quitinization of selected TLRs by TRIAD3A, an E3 ubiquitin-protein ligase
  • TRIAD3A is a RING finger protein that can bind to TLR4 and TLR9, and to a lesser extent TLR3 and TLR5, catalyzing the ubiquitization of these molecules
  • Overexpression of TRIAD3A promoted the nearly complete degradation of TLR4 and TLR9; this reduction was reflected in the decreased signal-specific activation by ligands specific for these TLRs
  • Conversely, depletion of TRIAD3A resulted in enhanced TLR activation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5110866

--


Antigen:
RNF216

Classification:
Polyclonal

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9NWF9

Gene Symbols:
RNF216

Immunogen:
Recombinant Protein corresonding to Human RNF216

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Gene:
RNF216

Gene Alias:
2810055G22Rik; AI647468; AU019462; C86502; CAHH; E3 ubiquitin ligase; E3 ubiquitin-protein ligase RNF216; F830018F18Rik; RGD1565135; RING finger protein 216; RING-type E3 ubiquitin transferase RNF216; RNF216; Triad domain-containing protein 3; TRIAD3; triad3a; U7I1; UBCE7IP1; UbcM4-interacting protein 83; ubiquitin-conjugating enzyme 7-interacting protein 1; Uip83; Zin; zinc finger protein inhibiting NF-kappa-B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54476

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA5110867

--


Antigen:
RCAS1

Classification:
Polyclonal

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O00559

Gene Symbols:
EBAG9

Immunogen:
Recombinant Protein corresonding to Human RCAS1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Gene:
EBAG9

Gene Alias:
AI835379; BAG9; cancer associated surface antigen; cancer associated surface antigen RCAS1; cancer-associated surface antigen RCAS1; EB9; EBAG9; estrogen receptor binding fragment associated gene 9; estrogen receptor binding site associated, antigen, 9; estrogen receptor-binding fragment-associated gene 9; estrogen receptor-binding fragment-associated gene 9 protein; HGNC:3123; PDAF; Rcas1; receptor binding cancer antigen expressed on SiSo cells; Receptor-binding cancer antigen expressed on SiSo cells

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9166

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA5110869

--


Antigen:
HTRA3

Classification:
Polyclonal

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P83110

Gene Symbols:
HTRA3

Immunogen:
Recombinant Protein corresonding to Human HTRA3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Gene:
HTRA3

Gene Alias:
2210021K23Rik; 9530081K03Rik; High-temperature requirement factor A3; HtrA serine peptidase 3; Htra3; Pregnancy-related serine protease; probable serine protease HTRA3; Prsp; RGD1308120; Serine protease HTRA3; Tasp; Toll-associated serine protease

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
94031

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA5110870

--


Antigen:
KLHL1

Classification:
Polyclonal

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9NR64

Gene Symbols:
KLHL1

Immunogen:
Recombinant Protein corresonding to Human KLHL1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Gene:
KLHL1

Gene Alias:
FLJ30047; kelch like family member 1; kelch-l like; kelch-like 1; kelch-like family member 1; kelch-like protein 1; KIAA1490; Klhl1; Mayven-related protein 2; mKIAA1490; MRP2; RP11-394C23.1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57626

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid