PIPA5111063

TREX1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5111063-Each-of-1 In Stock ₹ 47,015.22

PIPA5111063 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

TREX1

Classification

Polyclonal

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9NSU2

Gene Symbols

TREX1

Immunogen

Recombinant Protein corresonding to Human TREX1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry

Conjugate

Unconjugated

Gene

TREX1

Gene Alias

1661; 3' repair exonuclease 1; 3'-5' exonuclease TREX1; AGS1; AU041952; CRV; Deoxyribonuclease III; DNase III; DRN3; HERNS; RGD1309596; three prime exonuclease 1; three prime repair exonuclease 1; three-prime repair exonuclease 1; Trex1; trophoblast expressed 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11277

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • Immunogen sequence: PPPTVPPPPR VVDKLSLCVA PGKACSPAAS EITGLSTAVL AAHGRQCFDD NLANLLLAFL RRQPQPWCLV AHNGDRYD Trex1 (ATRIP) is the major human 3' to 5' exonuclease which is required for checkpoint signaling after DNA damage
  • It is ubiquitously expressed, binds to single stranded DNA coated with replication protein A that accumulates at sites of DNA damage and recruits the ataxia telangiectasia and Rad3 related protein (ATR), a checkpoint kinase, to sites of DNA damage and replication stress
  • Trex1 is required for ATR expression
  • This gene uses two different open reading frames
  • The upstream ORF encodes proteins which interact with ATR and localize to intranuclear foci induced by DNA damage and are essential components of the DNA damage checkpoint
  • The downstream ORF encodes proteins with 3' to 5' exonuclease activity and may be a subunit of human DNA polymerase III
  • Multiple transcript variants encoding different isoforms have been found
  • Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis.

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Img

Thermo Scientific

PIPA5111063

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Antigen:
TREX1

Classification:
Polyclonal

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9NSU2

Gene Symbols:
TREX1

Immunogen:
Recombinant Protein corresonding to Human TREX1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Gene:
TREX1

Gene Alias:
1661; 3' repair exonuclease 1; 3'-5' exonuclease TREX1; AGS1; AU041952; CRV; Deoxyribonuclease III; DNase III; DRN3; HERNS; RGD1309596; three prime exonuclease 1; three prime repair exonuclease 1; three-prime repair exonuclease 1; Trex1; trophoblast expressed 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11277

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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Thermo Scientific

PIPA5111064

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Antigen:
ECHDC1

Classification:
Polyclonal

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9NTX5

Gene Symbols:
ECHDC1

Immunogen:
Recombinant Protein corresonding to Human ECHDC1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry

Conjugate:
Unconjugated

Gene:
ECHDC1

Gene Alias:
1700028A24Rik; AI314462; AI930038; D10Ertd667e; dJ351K20.2; ECHDC1; enoyl CoA hydratase domain containing 1; enoyl Coenzyme A hydratase domain containing 1; enoyl Coenzyme A hydratase domain containing 1 isoform 2; enoyl-CoA hydratase domain-containing 1-like protein; enoyl-CoA hydratase domain-containing protein 1; enoyl-CoA hydratase domain-containing protein-like protein; epididymis secretory protein Li 76; ethylmalonyl-CoA decarboxylase; ethylmalonyl-CoA decarboxylase 1; HEL-S-76; Methylmalonyl-CoA decarboxylase; MMCD

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55862

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA5111065

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Antigen:
CRMP1

Classification:
Polyclonal

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q14194

Gene Symbols:
CRMP1

Immunogen:
Recombinant Protein corresonding to Human CRMP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
CRMP1

Gene Alias:
Collapsin response mediator protein 1; Crmp1; CRMP-1; dihydropyrimidinase-like 1; dihydropyrimidinase-related protein 1; Dpysl1; DRP1; DRP-1; Ulip3; ULIP-3; Unc-33-like phosphoprotein 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1400

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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Thermo Scientific

PIPA5111068

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Antigen:
ZNF488

Classification:
Polyclonal

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96MN9

Gene Symbols:
ZNF488

Immunogen:
Recombinant Protein corresonding to Human ZNF488

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry

Conjugate:
Unconjugated

Gene:
ZNF488

Gene Alias:
Gm1206; Zfp488; Zinc finger protein 488; Znf488

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
118738

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid