PIPA5111643

GTF3C3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5111643-Each-of-1 In Stock ₹ 47,015.22

PIPA5111643 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

GTF3C3

Classification

Polyclonal

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9Y5Q9

Gene Symbols

GTF3C3

Immunogen

Recombinant Protein corresonding to Human GTF3C3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry

Conjugate

Unconjugated

Gene

GTF3C3

Gene Alias

AL022818; general transcription factor 3C polypeptide 3; general transcription factor IIIC subunit 3; general transcription factor IIIC, polypeptide 3; general transcription factor IIIC, polypeptide 3, 102kDa; GTF3C3; im:7136784; LOC553318 protein; TF3C3; TF3C-gamma; TFIIIC 102 kDa subunit; TFIIIC102; TFiiiC2-102; TFIIICgamma; Transcription factor IIIC 102 kDa subunit; Transcription factor IIIC subunit gamma; transcription factor IIIC-gamma subunit

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9330

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Immunogen sequence: RETKKMMKEK RPRSKLPRAL RGLMGEANIR FARGEREEAI LMCMEIIRQA PLAYEPFSTL AMIYEDQGDM EKSLQFELIA AHLNPSDTEE WVRLAEMSLE QDNIKQAIFC YTKALKYEPT NVRYLWERSS LYEQMGD RNA polymerase (pol) III synthesizes tRNA, 5s rRNA, 7SL RNA and U6 snRNA and is overexpressed in many transformed cell lines and tumors in vivo, since cells must duplicate its protein components before division
  • Therefore, in order to maintain rapid growth, cells must produce a high level of Pol III transcribed RNA, which requires the presence of the TFIIIB and TFIIIC2 transcription factor complexes
  • The TFIIIC2 complex is composed of five subunits, TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, that are overexpressed in adenovirus transformed cells as well as in malignant cells in vivo, such as ovarian carcinomas
  • TFIIIC2 recruits RNA pol III and TFIIIB to promoter elements and may be a key component in the deregulation of malignant cells
  • The TFIIIB complex includes the TATA-binding protein (TBP), TFIIB-related factor 1 (BRF1) and TFIIIB, the expression of which are also upregulated in transformed cells
  • In many carcinomas, the tumor suppressors retinoblastoma (RB) and p53 are inactivated, which affects their ability to bind and inactivate the function of TFIIIB.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5111643

--


Antigen:
GTF3C3

Classification:
Polyclonal

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9Y5Q9

Gene Symbols:
GTF3C3

Immunogen:
Recombinant Protein corresonding to Human GTF3C3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry

Conjugate:
Unconjugated

Gene:
GTF3C3

Gene Alias:
AL022818; general transcription factor 3C polypeptide 3; general transcription factor IIIC subunit 3; general transcription factor IIIC, polypeptide 3; general transcription factor IIIC, polypeptide 3, 102kDa; GTF3C3; im:7136784; LOC553318 protein; TF3C3; TF3C-gamma; TFIIIC 102 kDa subunit; TFIIIC102; TFiiiC2-102; TFIIICgamma; Transcription factor IIIC 102 kDa subunit; Transcription factor IIIC subunit gamma; transcription factor IIIC-gamma subunit

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9330

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

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PIPA5111644

--


Antigen:
CYP2S1

Classification:
Polyclonal

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96SQ9

Gene Symbols:
CYP2S1

Immunogen:
Recombinant Protein corresonding to Human CYP2S1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Gene:
CYP2S1

Gene Alias:
1200011C15Rik; AU041727; C79779; CYP2S1; CYPIIS1; cytochrome P450 2S1; cytochrome P450 family 2 subfamily S member 1; cytochrome P450, 2s1; cytochrome P450, family 2, subfamily S, polypeptide 1; cytochrome P540, subfamily IIS, polypeptide 1; Hydroperoxy icosatetraenoate dehydratase; Thromboxane-A synthase; UNQ891/PRO1906

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29785

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PIPA5111646

--


Antigen:
Artemis

Classification:
Polyclonal

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96SD1

Gene Symbols:
DCLRE1C

Immunogen:
Recombinant Protein corresonding to Human Artemis

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry

Conjugate:
Unconjugated

Gene:
DCLRE1C

Gene Alias:
9930121L06Rik; AI661365; Art; ARTEMIS; ASCID; A-SCID; Dclre1c; DCLRE1C protein; DCLREC1C; DNA cross-link repair 1A, PSO2 homolog; DNA cross-link repair 1C; DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae); DNA cross-link repair 1C protein; DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae); FLJ11360; hSNM1C; mArt; Protein artemis; Protein A-SCID; RS SCID; RS-SCID; SCIDA; severe combined immunodeficiency, type a (Athabascan); SNM1 homolog C; SNM1C; SNM1C antibody; Snm1l; SNM1-like protein; tein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64421

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PIPA5111649

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Antigen:
BLK

Classification:
Polyclonal

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P51451

Gene Symbols:
BLK

Immunogen:
Recombinant Protein corresonding to Human BLK

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry

Conjugate:
Unconjugated

Gene:
BLK

Gene Alias:
B lymphocyte kinase; B lymphoid kinase; B lymphoid tyrosine kinase; Blk; BLK nonreceptor tyrosine kinase; BLK proto-oncogene, Src family tyrosine kinase; MGC10442; MODY11; p55-Blk; tyrosine-protein kinase Blk

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
640

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid