PIPA5112114

DLAT Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5112114-Each-of-1 In Stock ₹ 41,453.82

PIPA5112114 - Each of 1

₹ 41,453.82

In Stock

Quantity

1

Base Price: ₹ 41,453.82

GST (18%): ₹ 7,461.688

Total Price: ₹ 48,915.508

Antigen

DLAT

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DLAT

Gene Alias

6332404G05Rik; 70 kDa mitochondrial autoantigen of primary biliary cirrhosis; anti DLAT; Dihydrolipoamide; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; dihydrolipoamide S-acetyltransferase; dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex); dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial; DLAT; DLTA; E2; E2 component of pyruvate dehydrogenase complex; EC 2.3.1.12; M2 antigen complex 70 kDa subunit; ODP2; PBC; PDC PDC-E2; PDCE2; PDC-E2; pyruvate dehydrogenase complex component E2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1737

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P10515

Gene Symbols

DLAT

Immunogen

A synthetic peptide corresponding to the center region of the Human DLAT

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • DLAT encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC)
  • PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A
  • The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A
  • Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies
  • These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC)
  • In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed
  • PBC eventually leads to cirrhosis and liver failure.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5112114

--


Antigen:
DLAT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DLAT

Gene Alias:
6332404G05Rik; 70 kDa mitochondrial autoantigen of primary biliary cirrhosis; anti DLAT; Dihydrolipoamide; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; dihydrolipoamide S-acetyltransferase; dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex); dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial; DLAT; DLTA; E2; E2 component of pyruvate dehydrogenase complex; EC 2.3.1.12; M2 antigen complex 70 kDa subunit; ODP2; PBC; PDC PDC-E2; PDCE2; PDC-E2; pyruvate dehydrogenase complex component E2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1737

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P10515

Gene Symbols:
DLAT

Immunogen:
A synthetic peptide corresponding to the center region of the Human DLAT

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5112115

--


Antigen:
FAM96B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CIAO2B

Gene Alias:
1110019N10Rik; CGI-128; CIAB; Ciao2b; Cytosolic iron-sulfur assembly component 2B; Fam96b; family with sequence similarity 96 member B; family with sequence similarity 96, member B; HSPC118; MIP18; Mitotic spindle-associated MMXD complex subunit MIP18; MSS19-interacting protein of 18 kDa; Protein FAM96B; RGD1311762

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
51647

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
__

Formulation:
PBS with no preservative

Gene Accession No.:
Q9Y3D0

Gene Symbols:
CIAO2B

Immunogen:
A synthetic peptide corresponding to the N-terminus of the Human FAM96B/CIAO2B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5112117

--


Antigen:
Sostdc1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SOSTDC1

Gene Alias:
0610006G05Rik; CDA019; cystine-knot containing secreted protein; DAND7; Ectodermal BMP inhibitor; ECTODIN; sclerostin domain containing 1; sclerostin domain-containing protein 1; Sclerostin-like protein; similar to cystine knot-containing secreted protein; Sostdc1; Sostl; USAG1; USAG-1; Uterine sensitization-associated gene 1 protein; uterine sensitization-associated protein 1; uterine sensitization-associated protein-1; Wise; Wnt-signaling modulator

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
66042

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q9CQN4

Gene Symbols:
SOSTDC1

Immunogen:
A synthetic peptide corresponding to the C-terminus of the Mouse SOSTDC1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5112118

--


Antigen:
COX17

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
COX17

Gene Alias:
AI037035; Cox17; COX17 cytochrome c oxidase assembly homolog; COX17 cytochrome c oxidase copper chaperone; COX17 homolog, cytochrome c oxidase assembly protein; COX17, cytochrome c oxidase copper chaperone; Cox17a; cytochrome c oxidase 17 copper chaperone; cytochrome c oxidase assembly homolog 17; cytochrome c oxidase assembly protein 17; cytochrome c oxidase copper chaperone; cytochrome c oxidase subunit XVII assembly protein homolog; cytochrome c oxidase, subunit XVII assembly protein homolog; human homolog of yeast mitochondrial copper recruitment

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10063

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q14061

Gene Symbols:
COX17

Immunogen:
A synthetic peptide corresponding to the center region of the Human COX17

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG