PIPA5112197

SUMO4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5112197-Each-of-1 In Stock ₹ 41,453.82

PIPA5112197 - Each of 1

₹ 41,453.82

In Stock

Quantity

1

Base Price: ₹ 41,453.82

GST (18%): ₹ 7,461.688

Total Price: ₹ 48,915.508

Antigen

SUMO4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SUMO4

Gene Alias

dJ281H8.4; IDDM5; insulin-dependent diabetes mellitus 5; small ubiquitin-like modifier 4; small ubiquitin-like modifier 4 protein; Small ubiquitin-like protein 4; Small ubiquitin-related modifier 4; SMT3 suppressor of mif two 3 homolog 2; SMT3 suppressor of mif two 3 homolog 2-like; SMT3 suppressor of mif two 3 homolog 4; SMT3H4; SUMO 4; Sumo2l; SUMO4; SUMO-4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

387082

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.03% ProClin 300; pH 7

Gene Accession No.

Q6EEV6

Gene Symbols

SUMO4

Immunogen

E. coli-derived Human SUMO4 fragment

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • SUMO4 is a member of the SUMO gene family
  • This family of small ubiquitin-related modifiers covalently modify target lysines in proteins and control the target proteins' subcellular localization, stability, or activity
  • Upon oxidative stress, SUMO4 conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins
  • This protein may also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity
  • Covalent attachment to SUMO4 substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I
  • In contrast to SUMO1, SUMO2 and SUMO3, SUMO4 seems to be insensitive to sentrin-specific proteases due to the presence of Pro-90
  • This may impair processing to mature form and conjugation to substrates
  • SUMO4 is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene
  • The M55V substitution has been associated with type I diabetes.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5112197

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Antigen:
SUMO4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SUMO4

Gene Alias:
dJ281H8.4; IDDM5; insulin-dependent diabetes mellitus 5; small ubiquitin-like modifier 4; small ubiquitin-like modifier 4 protein; Small ubiquitin-like protein 4; Small ubiquitin-related modifier 4; SMT3 suppressor of mif two 3 homolog 2; SMT3 suppressor of mif two 3 homolog 2-like; SMT3 suppressor of mif two 3 homolog 4; SMT3H4; SUMO 4; Sumo2l; SUMO4; SUMO-4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
387082

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q6EEV6

Gene Symbols:
SUMO4

Immunogen:
E. coli-derived Human SUMO4 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5112202

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Antigen:
GPN1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gpn1

Gene Alias:
2410004J02Rik; AI449615; ATP(GTP)-binding protein; ATPBD1A; GPN1; GPN-loop GTPase 1; HUSSY-23; MBD2-interacting protein; MBDIN; methyl-CpG binding domain protein 2 interacting protein; NTPBP; RNA polymerase II associated protein 4; RNAPII-associated protein 4; RPAP4; XAB1; XPA binding protein 1; XPA binding protein 1, GTPase; XPA-binding protein 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11321

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q9HCN4

Gene Symbols:
Gpn1

Immunogen:
E. coli-derived Human XAB1/GPN1 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5112209

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Antigen:
RPS5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rps5

Gene Alias:
40S ribosomal protein S5; 40S ribosomal protein S5, N-terminally processed; AA617411; ribosomal protein S5; Rps5; S5; S5 ribosomal protein; Small ribosomal subunit protein uS7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6193

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
P46782

Gene Symbols:
Rps5

Immunogen:
E. coli-derived Human RPS5 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5112212

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Antigen:
RFXANK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RFXANK

Gene Alias:
ANKRA1; Ankyrin repeat family A protein 1; ankyrin repeat-containing regulatory factor X-associated protein; BLS; DNA-binding protein RFXANK; F14150_1; regulatory factor X associated ankyrin containing protein; regulatory factor X subunit B; Regulatory factor X-associated ankyrin-containing protein; RFXANK; RFXB; RFX-B; RFX-Bdelta4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
8625

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
O14593

Gene Symbols:
RFXANK

Immunogen:
E. coli-derived Human RFXANK fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG