PIPA511267

JAK2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA511267-Each-of-1 In Stock ₹ 47,186.34

PIPA511267 - Each of 1

₹ 47,186.34

In Stock

Quantity

1

Base Price: ₹ 47,186.34

GST (18%): ₹ 8,493.541

Total Price: ₹ 55,679.881

Antigen

JAK2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

JAK2

Gene Alias

EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2

Host Species

Rabbit

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

16452, 3717

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Western Blot

Concentration

2 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

O60674, Q62120

Gene Symbols

JAK2

Immunogen

KLH conjugated synthetic peptide between 1101-1132 amino acids from the C-terminal region of human JAK2

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera
  • This kinase contains the catalytic domain (JH1) of JAK2
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex
  • Mutations affecting JAK2 can cause Budd-Chiari syndrome, Polycythemia vera, Thrombocythemia 3, myelofibrosis, or Acute myelogenous leukemia.

Compare Similar Items

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Img

Thermo Scientific

PIPA511267

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Antigen:
JAK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JAK2

Gene Alias:
EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
16452, 3717

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
O60674, Q62120

Gene Symbols:
JAK2

Immunogen:
KLH conjugated synthetic peptide between 1101-1132 amino acids from the C-terminal region of human JAK2

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5112673

--


Antigen:
RPS11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPS11

Gene Alias:
40S ribosomal protein S11; ribosomal protein S11; RPS 11; RPS11; S11; Small ribosomal subunit protein uS17

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6205

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
P62280

Gene Symbols:
RPS11

Immunogen:
Recombinant Human 40S ribosomal protein S11 protein (2-158AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5112674

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Antigen:
Trypsin 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRSS2

Gene Alias:
anionic trypsin; anionic trypsin II; Anionic trypsin-2; anionic trypsinogen; EC 3.4.21; EC 3.4.21.4; MGC111183; MGC120174; MGC120175; pancreatic anionic trypsinogen; pancreatic trypsin 2; pancreatic trypsin II; pretrypsinogen II; protease serine 2 preproprotein; protease, serine 2; protease, serine, 2; protease, serine, 2 (trypsin 2); PRSS2; Ptryss2; Serine protease 2; Ta; Tesp4; Try2; TRY8; TRYP; TRYP2; TRYP8; trypsin 2; trypsin II; trypsin Trypsin II; Trypsin-2; trypsinogen 2; trypsinogen 20; trypsinogen anionic precursor

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
22072, 5645

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
6 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
P07146, P07478

Gene Symbols:
PRSS2

Immunogen:
Recombinant Human Trypsin-2 protein (24-247AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5112675

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Antigen:
PSEN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PSEN2

Gene Alias:
AD3L; AD3LP; AD4; Ad4h; AD5; Alg3; ALG-3; Alzheimer disease 4; CMD1V; E5-1; presenilin 2; presenilin-2; Presenilin-2 CTF subunit; Presenilin-2 NTF subunit; PS2; Ps-2; PSEN 2; PSEN2; Psnl2; STM2; STM-2

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5664, 81751

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
O88777, P49810

Gene Symbols:
PSEN2

Immunogen:
Recombinant Human Presenilin-2 protein (7-77AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG