PIPA5112717

SLFN11 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5112717-Each-of-1 In Stock ₹ 41,197.14

PIPA5112717 - Each of 1

₹ 41,197.14

In Stock

Quantity

1

Base Price: ₹ 41,197.14

GST (18%): ₹ 7,415.485

Total Price: ₹ 48,612.625

Antigen

SLFN11

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SLFN11

Gene Alias

schlafen family member 11; SLFN11; SLFN8/9

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

91607

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

3.5 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.

Q7Z7L1

Gene Symbols

SLFN11

Immunogen

Recombinant Human Schlafen family member 11 protein (670-821AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Inhibitor of DNA replication that promotes cell death in response to DNA damage (PubMed:22927417, PubMed:26658330, PubMed:29395061)
  • Acts as a guardian of the genome by killing cells with defective replication (PubMed:29395061)
  • Persistently blocks stressed replication forks by opening chromatin across replication initiation sites at stressed replication forks, possibly leading to unwind DNA ahead of the MCM helicase and block fork progression, μgtimately leading to cell death (PubMed:29395061)
  • Acts independently of ATR (PubMed:29395061)
  • Also acts as an interferon (IFN)-induced antiviral protein which acts as an inhibitor of retrovirus protein synthesis (PubMed:23000900)
  • Specifically abrogates the production of retroviruses such as human immunodeficiency virus 1 (HIV-1) by acting as a specific inhibitor of the synthesis of retroviruses encoded proteins in a codon-usage-dependent manner (PubMed:23000900)
  • Binds to tRNAs and exploits the unique viral codon bias towards A/T nucleotides (PubMed:23000900)
  • The exact inhibition mechanism is unclear: may either sequester tRNAs, prevent their maturation via post-transcriptional processing or may accelerate their deacylation (PubMed:23000900)
  • Does not inhibit reverse transcription, integration or production and nuclear export of viral RNA (PubMed:23000900)
  • [UniProt]

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5112717

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Antigen:
SLFN11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLFN11

Gene Alias:
schlafen family member 11; SLFN11; SLFN8/9

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
91607

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q7Z7L1

Gene Symbols:
SLFN11

Immunogen:
Recombinant Human Schlafen family member 11 protein (670-821AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5112718

--


Antigen:
SNRPD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SNRPD1

Gene Alias:
AA407109; AL023031; CHUNP6882; fk26a01; HsT2456; small nuclear ribonucleoprotein D1; small nuclear ribonucleoprotein D1 polypeptide; small nuclear ribonucleoprotein D1 polypeptide 16kDa; small nuclear ribonucleoprotein D1 polypeptide 16kDa pseudogene; small nuclear ribonucleoprotein D2 polypeptide 16.5kDa; small nuclear ribonucleoprotein Sm D1; Sm-D autoantigen; SMD1; sm-D1; snprd1; snRNP core protein D1; snrnpd1; SNRPD; Snrpd1; snrpd1 protein; wu:fk26a01; zgc:86929

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6632

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
P62314

Gene Symbols:
SNRPD1

Immunogen:
Recombinant Human Small nuclear ribonucleoprotein Sm D1 protein (1-119AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5112719

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Antigen:
SNX20

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SNX20

Gene Alias:
9130017C17Rik; RGD1307787; selectin ligand interactor cytoplasmic 1; selectin ligand interactor cytoplasmic-1; selectin ligand-interactor cytoplasmic 1; SLIC1; SLIC-1; SNX20; sorting nexin 20; sorting nexin-20

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
124460, 71607

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q7Z614, Q9D2Y5

Gene Symbols:
SNX20

Immunogen:
Recombinant Human Sorting nexin-20 protein (1-102AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5112720

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Antigen:
SOAT2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SOAT2

Gene Alias:
ACACT2; Acact-2; ACAT2; ACAT-2; acyl Co-A: cholesterol acyltransferase 2; acyl coenzyme A:cholesterol acyltransferase 2; acyl-CoA:cholesterol acyltransferase; acyl-CoA:cholesterol acyltransferase 2; acyl-coenzyme A:cholesterol acyltransferase 2; ARGP2; Cholesterol acyltransferase 2; D15Wsu97e; Soat2; Sterol O-acyltransferase 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8435

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.9 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O75908

Gene Symbols:
SOAT2

Immunogen:
Recombinant Human Sterol O-acyltransferase 2 protein (1-120AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG