PIPA5112826

HLA-DRB4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5112826-Each-of-1 In Stock ₹ 41,453.82

PIPA5112826 - Each of 1

₹ 41,453.82

In Stock

Quantity

1

Base Price: ₹ 41,453.82

GST (18%): ₹ 7,461.688

Total Price: ₹ 48,915.508

Antigen

HLA-DRB4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HLA-DRB4

Gene Alias

DR4; DR-4; DRB1 transplantation antigen; DRB4; HLA class II histocompatibility antigen, DR beta 4 chain; HLA-DR4B; HLA-DRB4; human leucocyte antigen DRB4; leukocyte antigen; major histocompatibility complex, class II, DR beta 4; MHC class II antigen DRB4; MHC class II antigen HLA-DR-beta; MHC class2 antigen; MHC HLA DR-beta chain

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

3126

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.

P13762

Gene Symbols

HLA-DRB4

Immunogen

Recombinant Human HLA class II histocompatibility antigen, DR beta 4 chain protein (30-227AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • HLA-DRB4 belongs to the HLA class II beta chain paralogues
  • This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane
  • It plays a central role in the immune system by presenting peptides derived from extracellular proteins
  • Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages)
  • The beta chain is approximately 26-28 kDa and its gene contains 6 exons
  • Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail
  • Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities
  • Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
  • DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5
  • The presence of DRB4 is linked with allelic variants of DRB1, otherwise it is omitted
  • There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9
  • HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5112826

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Antigen:
HLA-DRB4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HLA-DRB4

Gene Alias:
DR4; DR-4; DRB1 transplantation antigen; DRB4; HLA class II histocompatibility antigen, DR beta 4 chain; HLA-DR4B; HLA-DRB4; human leucocyte antigen DRB4; leukocyte antigen; major histocompatibility complex, class II, DR beta 4; MHC class II antigen DRB4; MHC class II antigen HLA-DR-beta; MHC class2 antigen; MHC HLA DR-beta chain

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3126

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
P13762

Gene Symbols:
HLA-DRB4

Immunogen:
Recombinant Human HLA class II histocompatibility antigen, DR beta 4 chain protein (30-227AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5112827

--


Antigen:
TUBA1B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TUBA1B

Gene Alias:
alpha tubulin; alpha-tubulin 2; Alpha-tubulin isotype M-alpha-2; alpha-tubulin ubiquitous; Detyrosinated tubulin alpha-1B chain; K-ALPHA-1; RGD1565476; Tuba1b; Tuba2; tubulin alpha 1b; tubulin alpha-1B chain; Tubulin alpha-2 chain; tubulin alpha-ubiquitous chain; Tubulin K-alpha-1; tubulin, alpha 1B; tubulin, alpha 2; tubulin, alpha, ubiquitous

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10376, 22143

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
P05213, P68363

Gene Symbols:
TUBA1B

Immunogen:
Recombinant Human Tubulin alpha-1B chain protein (29-310AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5112829

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Antigen:
GTPBP6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GTPBP6

Gene Alias:
AV119224; GTP binding protein 6 (putative); Gtpbp6; Pgbpll; pgpl; pseudoautosomal GTP binding protein-like, like; Pseudoautosomal GTP-binding protein-like; Putative GTP-binding protein 6; RGD1305954

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
8225

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
O43824

Gene Symbols:
GTPBP6

Immunogen:
Recombinant Human Putative GTP-binding protein 6 protein (146-295AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5112830

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Antigen:
TAX1BP3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TAX1BP3

Gene Alias:
1300011C24Rik; C20orf100; EMBL:AAH97976.1}; GCX1; glutaminase-interacting protein 3; Tax interaction protein 1; Tax1 (human T cell leukemia virus type I) binding protein 3; Tax1 (human T-cell leukemia virus type I) binding protein 3; Tax1 binding protein 3; tax1-binding protein 3; TAX1BP3; tax1bp3 {ECO:0000312; tax-interacting protein 1; TIP1; TIP-1

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
30851

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
O14907

Gene Symbols:
TAX1BP3

Immunogen:
Recombinant Human Tax1-binding protein 3 protein (1-124AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG