PIPA5112922

EXT1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5112922-Each-of-1 In Stock ₹ 40,854.90

PIPA5112922 - Each of 1

₹ 40,854.90

In Stock

Quantity

1

Base Price: ₹ 40,854.90

GST (18%): ₹ 7,353.882

Total Price: ₹ 48,208.782

Antigen

EXT1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

EXT1

Gene Alias

AA409028; exostoses (multiple) 1; exostosin 1; exostosin glycosyltransferase 1; exostosin-1; EXT; Ext1; Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N- acetylglucosaminyltransferase; glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Langer-Giedion syndrome chromosome region; LGCR; LGS; multiple exostoses protein 1; Multiple exostoses protein 1 homolog; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase; putative tumor suppressor protein EXT1; TRPS2; TTV

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

2131

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Western Blot

Concentration

3.25 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.

Q16394

Gene Symbols

EXT1

Immunogen

Recombinant Human Exostosin-1 protein (28-171AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Hereditary multiple exostoses (HME) is an autosomal dominant disorder characterized by the formation of exostoses (EXT), which are cartilage-capped bony protuberances mainly located on long bones
  • Two proteins associated with EXT, EXT1 and EXT2, form homo/heteromeric complexes in vivo, which leads to the accumulation of both proteins in the Golgi apparatus
  • EXT1 and EXT2 are endoplasmic reticulum-localized type II transmembrane glycoproteins that possess, or are tightly associated with, glycosyltransferase activities involved in the polymerization of the glycosaminoglycan, heparan sulfate (HS)
  • EXT2 is a protein that harbors the D-glucuronyl (GlcA) and N-acetyl-D-glucosaminyl (GlcNAc) transferase activities required for biosynthesis of HS
  • EXT1 rescues defective HS biosynthesis and elevates low GlcA and GlcNAc transferase levels in mutated cells.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5112922

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Antigen:
EXT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EXT1

Gene Alias:
AA409028; exostoses (multiple) 1; exostosin 1; exostosin glycosyltransferase 1; exostosin-1; EXT; Ext1; Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N- acetylglucosaminyltransferase; glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Langer-Giedion syndrome chromosome region; LGCR; LGS; multiple exostoses protein 1; Multiple exostoses protein 1 homolog; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase; putative tumor suppressor protein EXT1; TRPS2; TTV

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
2131

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
3.25 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q16394

Gene Symbols:
EXT1

Immunogen:
Recombinant Human Exostosin-1 protein (28-171AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5112923

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Antigen:
IQCB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Iqcb1

Gene Alias:
6820449I09Rik; AV128382; IQ calmodulin-binding motif containing 1; IQ calmodulin-binding motif-containing protein 1; IQ motif containing B1; IQCB1; KIAA0036; nephrocystin 5; Nephrocystin-5; NPHP5; OK/SW-cl.85; p53 and DNA damage-regulated IQ motif protein; PIQ; SLSN5

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
303915, 320299, 9657

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3.03 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q15051, Q8BP00

Gene Symbols:
Iqcb1

Immunogen:
Recombinant Human IQ calmodulin-binding motif-containing protein 1 protein (445-598AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5112924

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Antigen:
ZMYND11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZMYND11

Gene Alias:
2210402G22Rik; adenovirus 5 E1A-binding protein; Bone morphogenetic protein receptor-associated molecule 1; BRAM1; BS69; MGC111056; MRD30; Protein BS69; RP11-486H9.1; Unknown (protein for MGC:137432); zinc finger MYND domain-containing protein 11; Zinc finger MYND domain-containing protein 11-like protein; zinc finger MYND-type containing 11; zinc finger, MYND domain containing 11; zinc finger, MYND-type containing 11; ZMYND11

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10771, 66505

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Western Blot

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q15326, Q8R5C8

Gene Symbols:
ZMYND11

Immunogen:
Recombinant Human Zinc finger MYND domain-containing protein 11 protein (363-513AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5112926

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Antigen:
Laminin alpha-4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LAMA4

Gene Alias:
CMD1JJ; LAMA3; LAMA4; LAMA4*-1; laminin [a]4; laminin alpha 4 chain; laminin subunit alpha 4; laminin subunit alpha-4; laminin, alpha 4; laminin-14 subunit alpha; Laminin-8 subunit alpha; laminin-9 subunit alpha; RGD1560062

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3910

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Western Blot

Concentration:
0.23 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q16363

Gene Symbols:
LAMA4

Immunogen:
Recombinant Human Laminin subunit alpha-4 protein (1593-1823AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG