PIPA5113015
NHLRC1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5113015-Each-of-1 | In Stock | ₹ 43,336.14 |
PIPA5113015 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,336.14
GST (18%): ₹ 7,800.505
Total Price: ₹ 51,136.645
Antigen
NHLRC1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NHLRC1
Gene Alias
AI505271; B230309E09Rik; bA204B7.2; E3 ubiquitin-protein ligase NHLRC1; EPM2A; EPM2B; Malin; NHL repeat containing 1; NHL repeat containing E3 ubiquitin protein ligase 1; NHL repeat-containing protein 1; NHLRC1; RING-type E3 ubiquitin transferase NHLRC1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
364682, 378884
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Applications
ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration
3.63 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q6IMG5, Q6VVB1
Gene Symbols
NHLRC1
Immunogen
Recombinant Human E3 ubiquitin-protein ligase NHLRC1 protein (1-280AA)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Progressive myoclonic epilepsy type 2 (EPM2), also called Lafora disease, is an autosomal recessive disease characterized by grand mal seizures and/or myoclonus at about 15 years of age
- Rapid and severe mental deterioration follows, often with psychotic features
- Survival is less than 10 years after onset
- Starch-like, endoplasmic reticulum-associated polyglucosans, called Lafora bodies, can be observed in brain, muscle, liver and heart
- One cause of Lafora disease is due to mutations in NHLRC1, the gene encoding Malin
- Forty-nine different mutations in NHLRC1 have been shown to cause EPM2
- Malin, also called NHL repeat-containing protein 1, is a single subunit E3 ubiquitin ligase, containing 6 NHL repeats and 1 RING-type zinc finger
- Malin's RING domain is responsible for its ability to mediate ubiquitination
- Malin interacts with and polyubiquitinates Laforin, a protein also implicated in EPM2
- Malin localizes to the endoplasmic reticulum and, to a lesser extent, in the nucleus
- Malin is expressed in brain, cerebellum, spinal cord, medulla, heart, liver, skeletal muscle and pancreas.
Compare Similar Items
Show Difference
Antigen: NHLRC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NHLRC1
Gene Alias: AI505271; B230309E09Rik; bA204B7.2; E3 ubiquitin-protein ligase NHLRC1; EPM2A; EPM2B; Malin; NHL repeat containing 1; NHL repeat containing E3 ubiquitin protein ligase 1; NHL repeat-containing protein 1; NHLRC1; RING-type E3 ubiquitin transferase NHLRC1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 364682, 378884
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration: 3.63 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q6IMG5, Q6VVB1
Gene Symbols: NHLRC1
Immunogen: Recombinant Human E3 ubiquitin-protein ligase NHLRC1 protein (1-280AA)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
NHLRC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NHLRC1
Gene Alias:
AI505271; B230309E09Rik; bA204B7.2; E3 ubiquitin-protein ligase NHLRC1; EPM2A; EPM2B; Malin; NHL repeat containing 1; NHL repeat containing E3 ubiquitin protein ligase 1; NHL repeat-containing protein 1; NHLRC1; RING-type E3 ubiquitin transferase NHLRC1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
364682, 378884
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration:
3.63 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q6IMG5, Q6VVB1
Gene Symbols:
NHLRC1
Immunogen:
Recombinant Human E3 ubiquitin-protein ligase NHLRC1 protein (1-280AA)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: RAD9B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RAD9B
Gene Alias: A630082N15Rik; BC021784; Cell cycle checkpoint control protein RAD9B; cell cycle checkpoint control protein RAD9B homolog; DNA repair exonuclease rad9 homolog B; hRAD9B; mRAD9B; RAD9 checkpoint clamp component B; RAD9 homolog B; RAD9B
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 144715, 231724
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Western Blot
Concentration: 3.03 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: Q6WBX7, Q6WBX8
Gene Symbols: RAD9B
Immunogen: Recombinant Human Cell cycle checkpoint control protein RAD9B protein (274-408AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
RAD9B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RAD9B
Gene Alias:
A630082N15Rik; BC021784; Cell cycle checkpoint control protein RAD9B; cell cycle checkpoint control protein RAD9B homolog; DNA repair exonuclease rad9 homolog B; hRAD9B; mRAD9B; RAD9 checkpoint clamp component B; RAD9 homolog B; RAD9B
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
144715, 231724
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Western Blot
Concentration:
3.03 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
Q6WBX7, Q6WBX8
Gene Symbols:
RAD9B
Immunogen:
Recombinant Human Cell cycle checkpoint control protein RAD9B protein (274-408AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: AHSA2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ahsa2
Gene Alias: activator of 90 kDa heat shock protein ATPase homolog 2; activator of heat shock protein ATPase homolog 2; AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast); AHA1, activator of heat shock protein ATPase 2; AHA1, activator of heat shock protein ATPase homolog 2; Ahsa2; Hch1
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 130872, 268390, 305577
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration: 4 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: Q719I0, Q8N9S3
Gene Symbols: Ahsa2
Immunogen: Recombinant Human Putative activator of 90 kDa heat shock protein ATPase homolog 2 protein (1-137AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
AHSA2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ahsa2
Gene Alias:
activator of 90 kDa heat shock protein ATPase homolog 2; activator of heat shock protein ATPase homolog 2; AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast); AHA1, activator of heat shock protein ATPase 2; AHA1, activator of heat shock protein ATPase homolog 2; Ahsa2; Hch1
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
130872, 268390, 305577
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration:
4 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
Q719I0, Q8N9S3
Gene Symbols:
Ahsa2
Immunogen:
Recombinant Human Putative activator of 90 kDa heat shock protein ATPase homolog 2 protein (1-137AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: LRRC31
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LRRC31
Gene Alias: E230002P03Rik; epididymis secretory protein Li 293; HEL-S-293; leucine rich repeat containing 31; leucine-rich repeat-containing protein 31; Lrrc31; UNQ9367/PRO34156
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 320352, 79782
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.5 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: Q6UY01
Gene Symbols: LRRC31
Immunogen: Recombinant Human Leucine-rich repeat-containing protein 31 protein (1-300AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
LRRC31
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LRRC31
Gene Alias:
E230002P03Rik; epididymis secretory protein Li 293; HEL-S-293; leucine rich repeat containing 31; leucine-rich repeat-containing protein 31; Lrrc31; UNQ9367/PRO34156
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
320352, 79782
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
Q6UY01
Gene Symbols:
LRRC31
Immunogen:
Recombinant Human Leucine-rich repeat-containing protein 31 protein (1-300AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG