PIPA5113048

ALKBH2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5113048-Each-of-1 In Stock ₹ 41,197.14

PIPA5113048 - Each of 1

₹ 41,197.14

In Stock

Quantity

1

Base Price: ₹ 41,197.14

GST (18%): ₹ 7,415.485

Total Price: ₹ 48,612.625

Antigen

ALKBH2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ALKBH2

Gene Alias

2OG-Fe(II) oxy DC1; 9530023G02; Abh2; AlkB homolog 2; alkB homolog 2, alpha-ketoglutarate dependent dioxygenase; alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase; alkB, alkylation repair homolog 2; alkB, alkylation repair homolog 2 (E. coli); ALKBH2; Alkylated DNA repair protein alkB homolog 2; alpha-ketoglutarate-dependent dioxygenase alkB homolog 2; AU016977; DNA oxidative demethylase ALKBH2; mABH2; oxy DC1; RGD1306377

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

121642

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.23 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q6NS38

Gene Symbols

ALKBH2

Immunogen

Recombinant Human DNA oxidative demethylase ALKBH2 protein (1-261AA)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The E
  • coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA; ALKBH2 and ALKBH3 are mammalian homologs of AlkB that catalyze the removal of 1-methyladenine and 3-methylcytosine, modifications that left unchecked could lead to cancerous cells
  • Mutations in both ALKBH2 and ALKBH3 have been observed in pediatric brain tumors indicating that these proteins are important in the prevention of cancer formation
  • Like the histone demethylase JMJD1A, ALKBH2 is a non-heme iron enzyme that is inhibited by Nickel ions, suggesting that inhibition of ALKBH2 by Nickel ions may play a role in the development of cancer
  • Conversely, ALKBH2 mRNA and protein levels are increased glioma cells following Photofrin-mediated photodynamic therapy, an adjuvant therapy in cancer treatment, suggesting that down-regulating ALKBH2 expression in cancer cells may enhance the anti-cancer effectiveness of this treatment.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5113048

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Antigen:
ALKBH2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ALKBH2

Gene Alias:
2OG-Fe(II) oxy DC1; 9530023G02; Abh2; AlkB homolog 2; alkB homolog 2, alpha-ketoglutarate dependent dioxygenase; alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase; alkB, alkylation repair homolog 2; alkB, alkylation repair homolog 2 (E. coli); ALKBH2; Alkylated DNA repair protein alkB homolog 2; alpha-ketoglutarate-dependent dioxygenase alkB homolog 2; AU016977; DNA oxidative demethylase ALKBH2; mABH2; oxy DC1; RGD1306377

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
121642

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.23 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q6NS38

Gene Symbols:
ALKBH2

Immunogen:
Recombinant Human DNA oxidative demethylase ALKBH2 protein (1-261AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5113049

--


Antigen:
CPLX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CPLX2

Gene Alias:
921-L; AI413745; AW492120; complexin 2; complexin II; Complexin-2; CPLX2; CPX II; CPX2; CPX-2; CPX-II; DKFZp547D155; Hfb1; LOW QUALITY PROTEIN: complexin-2; MGC138492; synaphin; synaphin 1; synaphin-1; wu:fc27b12

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10814, 116657

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
0.73 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P84087, Q6PUV4

Gene Symbols:
CPLX2

Immunogen:
Recombinant Human Complexin-2 protein (1-134AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5113051

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Antigen:
SIGLEC15

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIGLEC15

Gene Alias:
CD33 antigen-like 3; CD33 molecule-like 3; Cd33l3; EG620235; HsT1361; RGD1565948; sialic acid binding Ig like lectin 15; sialic acid binding Ig-like lectin 15; sialic acid-binding Ig-like lectin 15; Siglec; Siglec 15; SIGLEC15; Siglec-15; SIGLEC-I

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
284266

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA

Concentration:
2.94 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q6ZMC9

Gene Symbols:
SIGLEC15

Immunogen:
Recombinant Human Sialic acid-binding Ig-like lectin 15 protein (20-263AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5113052

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Antigen:
FGD6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FGD6

Gene Alias:
FGD6; FYVE, RhoGEF and PH domain containing 6; FYVE, RhoGEF and PH domain-containing protein 6; KIAA1362; ZFYVE24; Zinc finger FYVE domain-containing protein 24

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
55785

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
4.7 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q6ZV73

Gene Symbols:
FGD6

Immunogen:
Recombinant Human FYVE, RhoGEF and PH domain-containing protein 6 protein (1138-1352AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG