PIPA5113397
EXD2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5113397-Each-of-1 | In Stock | ₹ 41,453.82 |
PIPA5113397 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,453.82
GST (18%): ₹ 7,461.688
Total Price: ₹ 48,915.508
Antigen
EXD2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
EXD2
Gene Alias
3'-5' exoribonuclease EXD2; 4930539P14Rik; C14orf114; C85658; EXD2; EXDL2; exonuclease 3'-5' domain containing 2; exonuclease 3'-5' domain-containing protein 2; exonuclease 3''-5'' domain-like 2; exonuclease 3'-5' domain-like 2; exonuclease 3'-5' domain-like-containing protein 2; RGD1311087
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
55218, 97827
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Applications
ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration
3.5 mg/mL
Formulation
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.
Q8VEG4, Q9NVH0
Gene Symbols
EXD2
Immunogen
Recombinant Human Exonuclease 3'-5' domain-containing protein 2 protein (137-245AA)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Description
- Exonuclease that has both 3'-5' exoribonuclease and exodeoxyribonuclease activities, depending on the divalent metal cation used as cofactor (PubMed:29335528, PubMed:31127291)
- In presence of Mg(2+), only shows 3'-5' exoribonuclease activity, while it shows both exoribonuclease and exodeoxyribonuclease activities in presence of Mn(2+) (PubMed:29335528, PubMed:31127291)
- Acts as an exoribonuclease in mitochondrion, possibly by regulating ATP production and mitochondrial translation (PubMed:29335528)
- Also involved in the response to DNA damage (PubMed:26807646, PubMed:31255466)
- Acts as 3'-5' exodeoxyribonuclease for double-strand breaks resection and efficient homologous recombination (PubMed:20603073, PubMed:26807646)
- Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks (PubMed:26807646)
- Also involved in response to replicative stress: recruited to stalled forks and is required to stabilize and restart stalled replication forks by restraining excessive fork regression, thereby suppressing their degradation (PubMed:31255466)
- [UniProt]
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Antigen: EXD2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EXD2
Gene Alias: 3'-5' exoribonuclease EXD2; 4930539P14Rik; C14orf114; C85658; EXD2; EXDL2; exonuclease 3'-5' domain containing 2; exonuclease 3'-5' domain-containing protein 2; exonuclease 3''-5'' domain-like 2; exonuclease 3'-5' domain-like 2; exonuclease 3'-5' domain-like-containing protein 2; RGD1311087
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 55218, 97827
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration: 3.5 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: Q8VEG4, Q9NVH0
Gene Symbols: EXD2
Immunogen: Recombinant Human Exonuclease 3'-5' domain-containing protein 2 protein (137-245AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
EXD2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EXD2
Gene Alias:
3'-5' exoribonuclease EXD2; 4930539P14Rik; C14orf114; C85658; EXD2; EXDL2; exonuclease 3'-5' domain containing 2; exonuclease 3'-5' domain-containing protein 2; exonuclease 3''-5'' domain-like 2; exonuclease 3'-5' domain-like 2; exonuclease 3'-5' domain-like-containing protein 2; RGD1311087
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
55218, 97827
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration:
3.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
Q8VEG4, Q9NVH0
Gene Symbols:
EXD2
Immunogen:
Recombinant Human Exonuclease 3'-5' domain-containing protein 2 protein (137-245AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: C1orf123
Classification: Polyclonal
Conjugate: Unconjugated
Gene: C1orf123
Gene Alias: C1orf123; chromosome 1 open reading frame 123; CXXC motif containing zinc binding protein; CZIB; UPF0587 protein C1orf123
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 54987
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration: 4 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: Q9NWV4
Gene Symbols: C1orf123
Immunogen: Recombinant Human UPF0587 protein C1orf123 protein (1-160AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
C1orf123
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
C1orf123
Gene Alias:
C1orf123; chromosome 1 open reading frame 123; CXXC motif containing zinc binding protein; CZIB; UPF0587 protein C1orf123
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
54987
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration:
4 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
Q9NWV4
Gene Symbols:
C1orf123
Immunogen:
Recombinant Human UPF0587 protein C1orf123 protein (1-160AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: TMOD3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Tmod3
Gene Alias: actin filament pointed-end capping protein; Tmod3; tropomodulin 3; tropomodulin 3 (ubiquitous); tropomodulin 3; ubiquitous tropomodulin; tropomodulin-3; Tropomodulin-3-like protein; Ubiquitous tropomodulin; ubiquitous tropomodulin U-Tmod; Unknown (protein for MGC:127550); UTMOD; U-Tmod
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 29766
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.49 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q9NYL9
Gene Symbols: Tmod3
Immunogen: Recombinant Human Tropomodulin-3 protein (1-352AA)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TMOD3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Tmod3
Gene Alias:
actin filament pointed-end capping protein; Tmod3; tropomodulin 3; tropomodulin 3 (ubiquitous); tropomodulin 3; ubiquitous tropomodulin; tropomodulin-3; Tropomodulin-3-like protein; Ubiquitous tropomodulin; ubiquitous tropomodulin U-Tmod; Unknown (protein for MGC:127550); UTMOD; U-Tmod
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29766
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.49 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q9NYL9
Gene Symbols:
Tmod3
Immunogen:
Recombinant Human Tropomodulin-3 protein (1-352AA)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ABI3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ABI3
Gene Alias: 2210414K06Rik; ABI family member 3; ABI family, member 3; ABI gene family member 3; ABI gene family, member 3; Abi3; AI987680; NESH; NESH protein; new molecule including SH3; SSH3BP3
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 51225, 66610
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.5 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: Q8BYZ1, Q9P2A4
Gene Symbols: ABI3
Immunogen: Recombinant Human ABI gene family member 3 protein (1-366AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
ABI3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ABI3
Gene Alias:
2210414K06Rik; ABI family member 3; ABI family, member 3; ABI gene family member 3; ABI gene family, member 3; Abi3; AI987680; NESH; NESH protein; new molecule including SH3; SSH3BP3
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
51225, 66610
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
Q8BYZ1, Q9P2A4
Gene Symbols:
ABI3
Immunogen:
Recombinant Human ABI gene family member 3 protein (1-366AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG