PIPA5113508
SHOC2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5113508-Each-of-1 | In Stock | ₹ 40,854.90 |
PIPA5113508 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,854.90
GST (18%): ₹ 7,353.882
Total Price: ₹ 48,208.782
Antigen
SHOC2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Shoc2
Gene Alias
AU017287; KIAA0862; Leucine-rich repeat protein SHOC-2; mKIAA0862; Protein soc-2 homolog; protein sur-8 homolog; Ras-binding protein SUR-8; RP11-348N5.2; Shoc2; SHOC2 leucine-rich repeat scaffold protein; SHOC2, leucine rich repeat scaffold protein; SIAA0862; SOC2; soc-2 (suppressor of clear) homolog; soc-2 (suppressor of clear) homolog (C. elegans); soc-2 suppressor of clear homolog; soc-2 suppressor of clear homolog (C. elegans); suppressor of clear, C. elegans, homolog of; SUR8
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
8036
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Applications
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
3 mg/mL
Formulation
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.
Q9UQ13
Gene Symbols
Shoc2
Immunogen
Recombinant Human Leucine-rich repeat protein SHOC-2 protein (3-89AA)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- SHOC2 protein participates in protein binding / transferase activity in the fibroblast growth factor receptor signaling pathway and Ras protein signal transduction
- It is a widely expressed protein composed almost entirely of leucine-rich repeats (LRR), with a lysine-rich sequence at the amino terminus and cytoplasmically localized
- SHOC2 acts as a positive modulator of the RAS-MAPK signaling cascade, which is elicited by EGL-15 and LET-23 and mediated by LET-60
- SHOC2 together with protein phosphatase 1c (PP1c) forms a highly specific M-Ras effector complex and is essential for activation of the MAPK pathway by growth factors
- Furthermore, in tumor cells with Ras gene mutations, inhibition of SHOC2 expression inhibits MAPK, but not PI3K activity
- The SHOC2-PP1c holoenzyme provides an attractive therapeutic target for inhibition of the MAPK pathway in cancer
- Recent studies show that aberrantly acquired N-myristoylation of SHOC2 causes human disease Noonan-like syndrome with loose anagen hair.
Compare Similar Items
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Antigen: SHOC2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Shoc2
Gene Alias: AU017287; KIAA0862; Leucine-rich repeat protein SHOC-2; mKIAA0862; Protein soc-2 homolog; protein sur-8 homolog; Ras-binding protein SUR-8; RP11-348N5.2; Shoc2; SHOC2 leucine-rich repeat scaffold protein; SHOC2, leucine rich repeat scaffold protein; SIAA0862; SOC2; soc-2 (suppressor of clear) homolog; soc-2 (suppressor of clear) homolog (C. elegans); soc-2 suppressor of clear homolog; soc-2 suppressor of clear homolog (C. elegans); suppressor of clear, C. elegans, homolog of; SUR8
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 8036
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 3 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: Q9UQ13
Gene Symbols: Shoc2
Immunogen: Recombinant Human Leucine-rich repeat protein SHOC-2 protein (3-89AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SHOC2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Shoc2
Gene Alias:
AU017287; KIAA0862; Leucine-rich repeat protein SHOC-2; mKIAA0862; Protein soc-2 homolog; protein sur-8 homolog; Ras-binding protein SUR-8; RP11-348N5.2; Shoc2; SHOC2 leucine-rich repeat scaffold protein; SHOC2, leucine rich repeat scaffold protein; SIAA0862; SOC2; soc-2 (suppressor of clear) homolog; soc-2 (suppressor of clear) homolog (C. elegans); soc-2 suppressor of clear homolog; soc-2 suppressor of clear homolog (C. elegans); suppressor of clear, C. elegans, homolog of; SUR8
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
8036
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
3 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
Q9UQ13
Gene Symbols:
Shoc2
Immunogen:
Recombinant Human Leucine-rich repeat protein SHOC-2 protein (3-89AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: FBXO4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FBXO4
Gene Alias: 1700096C12Rik; AI851261; AW494535; F-box only protein 4; F-box protein 4; F-box protein Fbx4; FBX4; Fbxo4
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26272
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.47 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q9UKT5
Gene Symbols: FBXO4
Immunogen: Recombinant Human F-box only protein 4 protein (138-387AA)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
FBXO4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FBXO4
Gene Alias:
1700096C12Rik; AI851261; AW494535; F-box only protein 4; F-box protein 4; F-box protein Fbx4; FBX4; Fbxo4
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26272
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.47 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q9UKT5
Gene Symbols:
FBXO4
Immunogen:
Recombinant Human F-box only protein 4 protein (138-387AA)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ICK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CILK1
Gene Alias: 2210420N10Rik; AI848300; ciliogenesis associated kinase 1; CILK1; ECO; heart serine-threonine protein kinase; hICK; iciliogenesis associated kinase 1; ICK; intestinal cell (MAK-like) kinase; intestinal cell kinase; KIAA0936; Laryngeal cancer kinase 2; LCK2; MAK-related kinase; mICK; MRK; serine/threonine protein kinase; serine/threonine-protein kinase ICK
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 22858
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration: 5 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: Q9UPZ9
Gene Symbols: CILK1
Immunogen: Recombinant Human Serine/threonine-protein kinase ICK protein (150-275AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ICK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CILK1
Gene Alias:
2210420N10Rik; AI848300; ciliogenesis associated kinase 1; CILK1; ECO; heart serine-threonine protein kinase; hICK; iciliogenesis associated kinase 1; ICK; intestinal cell (MAK-like) kinase; intestinal cell kinase; KIAA0936; Laryngeal cancer kinase 2; LCK2; MAK-related kinase; mICK; MRK; serine/threonine protein kinase; serine/threonine-protein kinase ICK
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
22858
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration:
5 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
Q9UPZ9
Gene Symbols:
CILK1
Immunogen:
Recombinant Human Serine/threonine-protein kinase ICK protein (150-275AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SLC13A4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Slc13a4
Gene Alias: 9630060C05Rik; Na(+)/sulfate cotransporter SUT-1; NAS2; SLC13A4; sodium sulfate cotransporter-2; solute carrier family 13 (sodium/sulfate symporter), member 4; solute carrier family 13 (sodium/sulfate symporters), member 4; solute carrier family 13 (sodium/sulphate symporters), member 4; solute carrier family 13 member 4; sulphate transporter 1; SUT1; SUT-1
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 26266
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 2 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: Q9UKG4
Gene Symbols: Slc13a4
Immunogen: Recombinant Human Solute carrier family 13 member 4 protein (134-273AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SLC13A4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Slc13a4
Gene Alias:
9630060C05Rik; Na(+)/sulfate cotransporter SUT-1; NAS2; SLC13A4; sodium sulfate cotransporter-2; solute carrier family 13 (sodium/sulfate symporter), member 4; solute carrier family 13 (sodium/sulfate symporters), member 4; solute carrier family 13 (sodium/sulphate symporters), member 4; solute carrier family 13 member 4; sulphate transporter 1; SUT1; SUT-1
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
26266
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
2 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
Q9UKG4
Gene Symbols:
Slc13a4
Immunogen:
Recombinant Human Solute carrier family 13 member 4 protein (134-273AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG