PIPA5113521

SCN8A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5113521-Each-of-1 In Stock ₹ 41,197.14

PIPA5113521 - Each of 1

₹ 41,197.14

In Stock

Quantity

1

Base Price: ₹ 41,197.14

GST (18%): ₹ 7,415.485

Total Price: ₹ 48,612.625

Antigen

SCN8A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Scn8a

Gene Alias

AI853486; ataxia 3; C630029C19Rik; CERIII; CIAT; dmu; EIEE13; hNa6/Scn8a voltage-gated sodium channel; MED; mnd2; mnd-2; Na+ channel; naCh6; Nav1.6; Nbna1; nmf2; nmf335; nmf58; nur14; peripheral nerve protein type 4; PN4; SCN8A; Scn8a (PN4); seal; Sodium channel 6; sodium channel protein type 8 subunit alpha; Sodium channel protein type VIII subunit alpha; sodium channel voltage-gated type VIII alpha polypeptide; sodium channel, voltage gated, type VIII alpha subunit; sodium channel, voltage gated, type VIII, alpha subunit; sodium channel, voltage-gated, type 8, alpha polypeptide; sodium channel, voltage-gated, type 8, alpha subunit; sodium channel, voltage-gated, type VIII, alpha; sodium channel, voltage-gated, type VIII, alpha polypeptide; sodium voltage-gated channel alpha subunit 8; voltage-gated sodium channel subunit alpha Nav1.6; voltage-gated sodium channel type VIII alpha protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

29710, 6334

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.53 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

O88420, Q9UQD0

Gene Symbols

Scn8a

Immunogen

Recombinant Human Sodium channel protein type 8 subunit alpha protein (1350-1440AA)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

Description

  • The sodium channel protein type 8 subunit alpha (Na+ CP type VIII alpha ) is a multi-pass, transmembrane protein that mediates the sodium ion permeability of excitable membranes
  • The three glycoproteins that comprise the voltage-gated sodium channel proteins include a pore-forming alpha subunit, a noncovalently associated beta1 subunit and a disulfide-linked beta2 subunit
  • The two beta subunits regulate the level of channel expression, modulate gating and function as cell adhesion molecules for cellular aggregation and cytoskeleton interaction
  • The alpha subunits of sodium channels type I and III are predominantly expressed in neuronal cell bodies and proximal processes, while type II alpha subunits are more abundant along axons
  • Sodium channels are important for rapid signal transduction but also play a significant role in neuronal development
  • Defects of the SCN8A gene have exhibited detrimental effects on the growth of secondary motoneurons
  • Loss of SCN8A expression will result in progressive paralysis and early death.

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Img

Thermo Scientific

PIPA5113521

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Antigen:
SCN8A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Scn8a

Gene Alias:
AI853486; ataxia 3; C630029C19Rik; CERIII; CIAT; dmu; EIEE13; hNa6/Scn8a voltage-gated sodium channel; MED; mnd2; mnd-2; Na+ channel; naCh6; Nav1.6; Nbna1; nmf2; nmf335; nmf58; nur14; peripheral nerve protein type 4; PN4; SCN8A; Scn8a (PN4); seal; Sodium channel 6; sodium channel protein type 8 subunit alpha; Sodium channel protein type VIII subunit alpha; sodium channel voltage-gated type VIII alpha polypeptide; sodium channel, voltage gated, type VIII alpha subunit; sodium channel, voltage gated, type VIII, alpha subunit; sodium channel, voltage-gated, type 8, alpha polypeptide; sodium channel, voltage-gated, type 8, alpha subunit; sodium channel, voltage-gated, type VIII, alpha; sodium channel, voltage-gated, type VIII, alpha polypeptide; sodium voltage-gated channel alpha subunit 8; voltage-gated sodium channel subunit alpha Nav1.6; voltage-gated sodium channel type VIII alpha protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29710, 6334

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.53 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O88420, Q9UQD0

Gene Symbols:
Scn8a

Immunogen:
Recombinant Human Sodium channel protein type 8 subunit alpha protein (1350-1440AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5113522

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Antigen:
FBXO3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FBXO3

Gene Alias:
1200002G09Rik; 1700026K02Rik; AI046358; DKFZp564B092; FBA; F-box only protein 3; F-box protein 3; F-box protein FBA; F-box protein FBX3; FBX3; FBXO3

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
26273, 57443

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
4 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q9DC63, Q9UK99

Gene Symbols:
FBXO3

Immunogen:
Recombinant Human F-box only protein 3 protein (276-376AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5113524

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Antigen:
DIMT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DIMT1

Gene Alias:
1500031M22Rik; 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase; 18S rRNA dimethylase; AV111347; DIM1; DIM1 dimethyladenosine transferase 1 homolog; DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae); DIM1 dimethyladenosine transferase 1-like; DIM1 dimethyladenosine transferase 1-like (S. cerevisiae); dimethyladenosine transferase; Dimt1; Dimt1l; HSA9761; HUSSY-05; HUSSY5; probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase; Probable 18S rRNA dimethylase; probable dimethyladenosine transferase; Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase; RGD1311752; S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
27292, 66254

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q9D0D4, Q9UNQ2

Gene Symbols:
DIMT1

Immunogen:
Recombinant Human Probable dimethyladenosine transferase protein (1-313AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5113526

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Antigen:
PPM1H

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPM1H

Gene Alias:
A430075L18Rik; ARHCL1; C030002B11Rik; KIAA1157; NERPP-2C; neurite extension-related protein phosphatase related to PP2C; Ppm1h; Protein phosphatase 1H; protein phosphatase 1H (PP2C domain containing); protein phosphatase, Mg2+/Mn2+ dependent 1H; protein phosphatase, Mg2+/Mn2+ dependent, 1H; ras homolog gene family, member C like 1; URCC2

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
319468, 57460

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
4 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q3UYC0, Q9ULR3

Gene Symbols:
PPM1H

Immunogen:
Recombinant Human Protein phosphatase 1H protein (73-289AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG