PIPA5113604

SCN8A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5113604-Each-of-1 In Stock ₹ 44,705.10

PIPA5113604 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SCN8A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Scn8a

Gene Alias

AI853486; ataxia 3; C630029C19Rik; CERIII; CIAT; dmu; EIEE13; hNa6/Scn8a voltage-gated sodium channel; MED; mnd2; mnd-2; Na+ channel; naCh6; Nav1.6; Nbna1; nmf2; nmf335; nmf58; nur14; peripheral nerve protein type 4; PN4; SCN8A; Scn8a (PN4); seal; Sodium channel 6; sodium channel protein type 8 subunit alpha; Sodium channel protein type VIII subunit alpha; sodium channel voltage-gated type VIII alpha polypeptide; sodium channel, voltage gated, type VIII alpha subunit; sodium channel, voltage gated, type VIII, alpha subunit; sodium channel, voltage-gated, type 8, alpha polypeptide; sodium channel, voltage-gated, type 8, alpha subunit; sodium channel, voltage-gated, type VIII, alpha; sodium channel, voltage-gated, type VIII, alpha polypeptide; sodium voltage-gated channel alpha subunit 8; voltage-gated sodium channel subunit alpha Nav1.6; voltage-gated sodium channel type VIII alpha protein

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6334

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.

Q9UQD0

Gene Symbols

Scn8a

Immunogen

Synthetic peptide directed towards the middle region of human SCN8A

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: ESDPEGSKDK LDDTSSSEGS TIDIKPEVEE VPVEQPEEYL DPDACFTEGC For short term use, store at 2-8°C up to 1 week
  • For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles
  • Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% The sodium channel protein type 8 subunit alpha (Na+ CP type VIII alpha ) is a multi-pass, transmembrane protein that mediates the sodium ion permeability of excitable membranes
  • The three glycoproteins that comprise the voltage-gated sodium channel proteins include a pore-forming alpha subunit, a noncovalently associated beta1 subunit and a disulfide-linked beta2 subunit
  • The two beta subunits regulate the level of channel expression, modulate gating and function as cell adhesion molecules for cellular aggregation and cytoskeleton interaction
  • The alpha subunits of sodium channels type I and III are predominantly expressed in neuronal cell bodies and proximal processes, while type II alpha subunits are more abundant along axons
  • Sodium channels are important for rapid signal transduction but also play a significant role in neuronal development
  • Defects of the SCN8A gene have exhibited detrimental effects on the growth of secondary motoneurons
  • Loss of SCN8A expression will result in progressive paralysis and early death.

Compare Similar Items

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Img

Thermo Scientific

PIPA5113604

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Antigen:
SCN8A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Scn8a

Gene Alias:
AI853486; ataxia 3; C630029C19Rik; CERIII; CIAT; dmu; EIEE13; hNa6/Scn8a voltage-gated sodium channel; MED; mnd2; mnd-2; Na+ channel; naCh6; Nav1.6; Nbna1; nmf2; nmf335; nmf58; nur14; peripheral nerve protein type 4; PN4; SCN8A; Scn8a (PN4); seal; Sodium channel 6; sodium channel protein type 8 subunit alpha; Sodium channel protein type VIII subunit alpha; sodium channel voltage-gated type VIII alpha polypeptide; sodium channel, voltage gated, type VIII alpha subunit; sodium channel, voltage gated, type VIII, alpha subunit; sodium channel, voltage-gated, type 8, alpha polypeptide; sodium channel, voltage-gated, type 8, alpha subunit; sodium channel, voltage-gated, type VIII, alpha; sodium channel, voltage-gated, type VIII, alpha polypeptide; sodium voltage-gated channel alpha subunit 8; voltage-gated sodium channel subunit alpha Nav1.6; voltage-gated sodium channel type VIII alpha protein

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6334

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q9UQD0

Gene Symbols:
Scn8a

Immunogen:
Synthetic peptide directed towards the middle region of human SCN8A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5113607

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Antigen:
KCNK13

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KCNK13

Gene Alias:
BB085247; F730021E22Rik; Gm1570; Gm1685; K2p13.1; K2P13.1 potassium channel; KCNK13; Potassium channel subfamily K member 13; potassium channel, subfamily K, member 13; potassium channel, two pore domain subfamily K, member 13; potassium two pore domain channel subfamily K member 13; prdx1; Tandem pore domain halothane-inhibited potassium channel 1; tandem pore domain potassium channel THIK-1; THIK1; THIK-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56659

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q9HB14

Gene Symbols:
KCNK13

Immunogen:
Synthetic peptide directed towards the C terminal region of human KCNK13

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5113610

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Antigen:
HTR3C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HTR3C

Gene Alias:
5-HT3C; 5-HT3-C; 5-hydroxytryptamine (serotonin) receptor 3, family member C; 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic; 5-hydroxytryptamine receptor 3 subunit C; 5-hydroxytryptamine receptor 3C; HTR3C; Serotonin receptor 3C

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170572

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q8WXA8

Gene Symbols:
HTR3C

Immunogen:
Synthetic peptide directed towards the middle region of human HTR3C

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5113613

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Antigen:
ASIC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ASIC2

Gene Alias:
ACCN; ACCN1; ACIC2; acid sensing (proton gated) ion channel 2; acid sensing ion channel 2; acid sensing ion channel subunit 2; acid-sensing (proton-gated) ion channel 2; acid-sensing ion channel 2; Amiloride-sensitive brain sodium channel; amiloride-sensitive brain sodium channel 2; Amiloride-sensitive cation channel 1, neuronal; amiloride-sensitive cation channel 1, neuronal (degenerin); Amiloride-sensitive cation channel neuronal 1; Asic2; ASIC2a; Bnac1; BNaC1a; BNC1; BNC1k; Brain sodium channel 1; degenerin; hBNaC1; Mammalian degenerin homolog; MDEG; MDEG1; MDEG2; neuronal amiloride-sensitive cation channel 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
40

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q16515

Gene Symbols:
ASIC2

Immunogen:
Synthetic peptide directed towards the middle region of human ACCN1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG