PIPA5113680

AIF Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5113680-Each-of-1 In Stock ₹ 44,705.10

PIPA5113680 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

AIF

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AIFM1

Gene Alias

AG1; AGR1; Aif; AIFM1; AIFsh2; apoptosis inducing factor mitochondria associated 1; apoptosis inducing factor, mitochondria associated 1; apoptosis-inducing factor 1, mitochondrial; apoptosis-inducing factor, mitochondrion-associated 1; apoptosis-inducing factor, mitochondrion-associated, 1; CMT2D; CMTX4; COWCK; COXPD6; DFNX5; ER protein 18; ER protein 19; ERP18; ERP19; hAG-1; harlequin; Hq; hTLP19; MGC111425; mitochondrial apoptosis-inducing factor 1; NADMR; NAMSD; pcd8; PDCD8; PDIA16; programmed cell death 8 (apoptosis-inducing factor); programmed cell death protein 8; RP3-438D16.2; striatal apoptosis-inducing factor; testicular secretory protein Li 4; TLP19; UNQ713/PRO1376

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

26926, 9131

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.

O95831, Q9Z0X1

Gene Symbols

AIFM1

Immunogen

Synthetic peptide directed towards the C terminal region of human PDCD8

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: VDSSLPTVGV FAKATAQDNP KSATEQSGTG IRSESETESE ASEITIPPST For short term use, store at 2-8°C up to 1 week
  • For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles
  • Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%; Sheep: 100%; Zebrafish: 79% Apoptosis Inducing Factor (AIF) causes chromatin condensation and DNA fragmentation
  • AIF was recently identified, and cloned
  • Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation
  • These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins
  • Like the critical molecules, cytochrome c and caspase-9, in apoptosis, AIF localizes in mitochondria
  • AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9
  • AIF induces chromatin condensation and large scale DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection and apoptosis stimuli
  • AIF is highly conserved between human and mouse and widely expressed
  • Mutations in the AIF gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy
  • Alternative splicing results in multiple transcript variants of AIF and a related pseudogene has been identified on chromosome 10.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5113680

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Antigen:
AIF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AIFM1

Gene Alias:
AG1; AGR1; Aif; AIFM1; AIFsh2; apoptosis inducing factor mitochondria associated 1; apoptosis inducing factor, mitochondria associated 1; apoptosis-inducing factor 1, mitochondrial; apoptosis-inducing factor, mitochondrion-associated 1; apoptosis-inducing factor, mitochondrion-associated, 1; CMT2D; CMTX4; COWCK; COXPD6; DFNX5; ER protein 18; ER protein 19; ERP18; ERP19; hAG-1; harlequin; Hq; hTLP19; MGC111425; mitochondrial apoptosis-inducing factor 1; NADMR; NAMSD; pcd8; PDCD8; PDIA16; programmed cell death 8 (apoptosis-inducing factor); programmed cell death protein 8; RP3-438D16.2; striatal apoptosis-inducing factor; testicular secretory protein Li 4; TLP19; UNQ713/PRO1376

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26926, 9131

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
O95831, Q9Z0X1

Gene Symbols:
AIFM1

Immunogen:
Synthetic peptide directed towards the C terminal region of human PDCD8

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5113681

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Antigen:
RBMS3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RBMS3

Gene Alias:
6720477E09Rik; 8430436O14Rik; RBMS3; RNA binding motif single stranded interacting protein 3; RNA binding motif, single stranded interacting protein; RNA binding motif, single stranded interacting protein 3; RNA-binding motif, single-stranded-interacting protein 3; RNA-binding protein; RNA-binding protein RBMS3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27303

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q6XE24

Gene Symbols:
RBMS3

Immunogen:
Synthetic peptide directed towards the middle region of human RBMS3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5113682

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Antigen:
APOBEC3F

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APOBEC3F

Gene Alias:
A3F; APOBEC3F; apolipoprotein B editing enzyme catalytic polypeptide-like 3F; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3F; apolipoprotein B mRNA editing enzyme catalytic subunit 3F; apolipoprotein B mRNA editing enzyme cytidine deaminase; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F; apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F; ARP8; BK150C2.4.MRNA; DNA dC->dU-editing enzyme APOBEC-3F; induced upon T-cell activation; KA6

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
200316

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q8IUX4

Gene Symbols:
APOBEC3F

Immunogen:
Synthetic peptide directed towards the middle region of human APOBEC3F

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5113683

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Antigen:
SERBP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SERBP1

Gene Alias:
1200009K13Rik; 9330147J08Rik; AL022786; CGI-55; CHD3IP; chromodomain helicase DNA binding protein 3 interacting protein; HABP4L; hypothetical RNA binding protein RDA288; MGC128417 protein; PAI RBP 1; PAI-1 mRNA binding protein; PAI-1 mRNA-binding protein; PAI1 RNA-binding protein 1; Pairbp1; PAI-RBP1; plasminogen activator inhibitor 1 RNA binding protein; plasminogen activator inhibitor 1 RNA-binding protein; Rda288; RNA binding protein RDA288; SERBP1; Serpine1 mRNA binding protein 1; SERPINE1 mRNA-binding protein 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26135

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q8NC51

Gene Symbols:
SERBP1

Immunogen:
Synthetic peptide directed towards the middle region of human SERBP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG