PIPA5113687
ADARB1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5113687-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5113687 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
ADARB1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ADARB1
Gene Alias
1700057H01Rik; Adar2; Adarb1; adenosine deaminase, RNA specific B1; adenosine deaminase, RNA-specific, B1; adenosine deaminase, RNA-specific, B1 (homolog of rat RED1); adenosine deaminase, RNA-specific, B1 (RED1 homolog rat); AW124433; AW558573; BB220382; D10Bwg0447e; Double-stranded RNA-specific editase 1; DRABA2; DRADA2; dsRNA adenosine deaminase; dsRNA adenosine deaminase DRADA2; Red1; RED1 homolog; RNA editase; RNA editing deaminase 1; RNA editing deaminase of glutamate receptors; RNA-editing deaminase 1; RNA-editing enzyme 1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
104
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.
P78563
Gene Symbols
ADARB1
Immunogen
Synthetic peptide directed towards the N terminal region of human ADARB1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: NMSSSSTDVK ENRNLDNVSP KDGSTPGPGE GSQLSNGGGG GPGRKRPLEE For short term use, store at 2-8°C up to 1 week
- For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles
- Predicted homology: Cow: 83%; Dog: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rat: 92% Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing
- This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences during viral RNA replication; and RNA structure-dependent activities such as microRNA production or targeting or protein-RNA interactions
- Can edit both viral and cellular RNAs and can edit RNAs at multiple sites (hyper-editing) or at specific sites (site-specific editing)
- Its cellular RNA substrates include: bladder cancer-associated protein (BLCAP), neurotransmitter receptors for glutamate (GRIA2 and GRIK2) and serotonin (HTR2C), GABA receptor (GABRA3) and potassium voltage-gated channel (KCNA1)
- Site-specific RNA editing of transcripts encoding these proteins results in amino acid substitutions which consequently alter their functional activities
- Edits GRIA2 at both the Q/R and R/G sites efficiently but converts the adenosine in hotspot1 much less efficiently
- Can exert a proviral effect towards human immunodeficiency virus type 1 (HIV-1) and enhances its replication via both an editing-dependent and editing-independent mechanism
- The former involves editing of adenosines in the 5'UTR while the latter occurs via suppression of EIF2AK2/PKR activation and function
- Can inhibit cell proliferation and migration and can stimulate exocytosis.
Compare Similar Items
Show Difference
Antigen: ADARB1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ADARB1
Gene Alias: 1700057H01Rik; Adar2; Adarb1; adenosine deaminase, RNA specific B1; adenosine deaminase, RNA-specific, B1; adenosine deaminase, RNA-specific, B1 (homolog of rat RED1); adenosine deaminase, RNA-specific, B1 (RED1 homolog rat); AW124433; AW558573; BB220382; D10Bwg0447e; Double-stranded RNA-specific editase 1; DRABA2; DRADA2; dsRNA adenosine deaminase; dsRNA adenosine deaminase DRADA2; Red1; RED1 homolog; RNA editase; RNA editing deaminase 1; RNA editing deaminase of glutamate receptors; RNA-editing deaminase 1; RNA-editing enzyme 1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 104
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.: P78563
Gene Symbols: ADARB1
Immunogen: Synthetic peptide directed towards the N terminal region of human ADARB1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ADARB1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ADARB1
Gene Alias:
1700057H01Rik; Adar2; Adarb1; adenosine deaminase, RNA specific B1; adenosine deaminase, RNA-specific, B1; adenosine deaminase, RNA-specific, B1 (homolog of rat RED1); adenosine deaminase, RNA-specific, B1 (RED1 homolog rat); AW124433; AW558573; BB220382; D10Bwg0447e; Double-stranded RNA-specific editase 1; DRABA2; DRADA2; dsRNA adenosine deaminase; dsRNA adenosine deaminase DRADA2; Red1; RED1 homolog; RNA editase; RNA editing deaminase 1; RNA editing deaminase of glutamate receptors; RNA-editing deaminase 1; RNA-editing enzyme 1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
104
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.:
P78563
Gene Symbols:
ADARB1
Immunogen:
Synthetic peptide directed towards the N terminal region of human ADARB1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: hnRNP L
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HNRNPL
Gene Alias: C79783; D830027H13Rik; Fblim1; FLJ35509; Heterogeneous nuclear ribonucleoprotein L; heterogenous nuclear ribonucleoprotein L; hnRNP L; Hnrnpl; hnRNP-L; Hnrpl; P/OKcl.14
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15388, 3191
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.: P14866, Q8R081
Gene Symbols: HNRNPL
Immunogen: Synthetic peptide directed towards the N terminal region of human HNRPL
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
hnRNP L
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HNRNPL
Gene Alias:
C79783; D830027H13Rik; Fblim1; FLJ35509; Heterogeneous nuclear ribonucleoprotein L; heterogenous nuclear ribonucleoprotein L; hnRNP L; Hnrnpl; hnRNP-L; Hnrpl; P/OKcl.14
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15388, 3191
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.:
P14866, Q8R081
Gene Symbols:
HNRNPL
Immunogen:
Synthetic peptide directed towards the N terminal region of human HNRPL
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: ISG20
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ISG20
Gene Alias: 1600023I01Rik; 2010107M23Rik; 20kDa; CD25; DnaQL; estrogen-regulated transcript 45 protein; HEM45; interferon stimulated exonuclease; interferon stimulated exonuclease 20; interferon stimulated exonuclease gene 20; interferon stimulated exonuclease gene 20kDa; interferon stimulated gene 20kDa; interferon-stimulated gene 20 kDa protein; interferon-stimulated protein; ISG20; Promyelocytic leukemia nuclear body-associated protein ISG20; Protein DnaQL
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3669
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.: Q96AZ6
Gene Symbols: ISG20
Immunogen: Synthetic peptide directed towards the middle region of human ISG20
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ISG20
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ISG20
Gene Alias:
1600023I01Rik; 2010107M23Rik; 20kDa; CD25; DnaQL; estrogen-regulated transcript 45 protein; HEM45; interferon stimulated exonuclease; interferon stimulated exonuclease 20; interferon stimulated exonuclease gene 20; interferon stimulated exonuclease gene 20kDa; interferon stimulated gene 20kDa; interferon-stimulated gene 20 kDa protein; interferon-stimulated protein; ISG20; Promyelocytic leukemia nuclear body-associated protein ISG20; Protein DnaQL
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3669
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.:
Q96AZ6
Gene Symbols:
ISG20
Immunogen:
Synthetic peptide directed towards the middle region of human ISG20
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Serglycin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SRGN
Gene Alias: gp600; hematopoetic proteoglycan core peptide; hematopoetic proteoglycan core protein; hematopoietic proteoglycan core protein; Mastocytoma proteoglycan core protein; p.PG; Platelet proteoglycan core protein; PPG; Prg; Prg1; proteoglycan 1, secretory granule; proteoglycan protein core for mast cell secretory granule; proteoglycan, secretory granule; secretory granule proteoglycan core peptide; secretory granule proteoglycan core protein; Serglycin; serglycin proteoglycan; Sgc; Srgn
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5552
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.: P10124
Gene Symbols: SRGN
Immunogen: Immunogen sequence: LLKCSRLVLA LALILVLESS VQGYPTRRAR YQWVRCNPDS NSANCLEEKG
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Serglycin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SRGN
Gene Alias:
gp600; hematopoetic proteoglycan core peptide; hematopoetic proteoglycan core protein; hematopoietic proteoglycan core protein; Mastocytoma proteoglycan core protein; p.PG; Platelet proteoglycan core protein; PPG; Prg; Prg1; proteoglycan 1, secretory granule; proteoglycan protein core for mast cell secretory granule; proteoglycan, secretory granule; secretory granule proteoglycan core peptide; secretory granule proteoglycan core protein; Serglycin; serglycin proteoglycan; Sgc; Srgn
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5552
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.:
P10124
Gene Symbols:
SRGN
Immunogen:
Immunogen sequence: LLKCSRLVLA LALILVLESS VQGYPTRRAR YQWVRCNPDS NSANCLEEKG
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG