PIPA5113707

RRP4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5113707-Each-of-1 In Stock ₹ 44,705.10

PIPA5113707 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

RRP4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

EXOSC2

Gene Alias

EXOSC2; Exosome complex component RRP4; exosome complex exonuclease RRP4; exosome component 2; homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4); homolog of Yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease; hRrp4p; p7; Ribosomal RNA-processing protein 4; RRP4; Rrp4p

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23404

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.

Q13868

Gene Symbols

EXOSC2

Immunogen

Synthetic peptide directed towards the middle region of human EXOSC2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: AEVQAVFSDG AVSLHTRSLK YGKLGQGVLV QVSPSLVKRQ KTHFHDLPCG For short term use, store at 2-8°C up to 1 week
  • For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles
  • Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events
  • In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm
  • The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates
  • In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs
  • It seems to be involved in degradation of histone mRNA
  • The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes
  • EXOSC2 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits through contacts with EXOSC4 and EXOSC7
  • [UniProt]

Compare Similar Items

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Img

Thermo Scientific

PIPA5113707

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Antigen:
RRP4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EXOSC2

Gene Alias:
EXOSC2; Exosome complex component RRP4; exosome complex exonuclease RRP4; exosome component 2; homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4); homolog of Yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease; hRrp4p; p7; Ribosomal RNA-processing protein 4; RRP4; Rrp4p

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23404

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q13868

Gene Symbols:
EXOSC2

Immunogen:
Synthetic peptide directed towards the middle region of human EXOSC2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5113708

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Antigen:
RBFOX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RBFOX2

Gene Alias:
dJ106I20.3; Fbm2; fox-1 homolog B; Fox-1 homolog Fxh; fox-1 homologue; FOX2; Fox-2; Fxh; Fyn-binding molecule 2; hexaribonucleotide-binding protein 2; HNRBP2; Hrnbp2; Rbfox2; Rbm9; repressor of tamoxifen transcriptional activity; RNA binding fox-1 homolog 2; RNA binding motif protein 9; RNA binding protein fox-1 homolog 2; RNA binding protein fox-1 homolog 2; RNA binding protein, fox-1 homolog (C. elegans) 2; RNA binding protein, fox-1 homolog (C. elegans) 2; RNA binding protein, fox-1 homolog 2; RNA-binding motif protein 9; RNA-binding protein 9; RTA; zgc:85694

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23543

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
O43251

Gene Symbols:
RBFOX2

Immunogen:
Synthetic peptide directed towards the middle region of human RBM9

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5113709

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Antigen:
ENOX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ENOX1

Gene Alias:
bA64J21.1; candidate growth-related and time keeping constitutive hydroquinone (NADH) oxidase; candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase; cCNOX; Cell proliferation-inducing gene 38 protein; CNOX; Constitutive Ecto-NOX; ecto-NOX disulfide-thiol exchanger 1; ENOX1; Hydroquinone [NADH] oxidase; PIG38; Protein disulfide-thiol oxidoreductase

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55068

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q8TC92

Gene Symbols:
ENOX1

Immunogen:
Synthetic peptide directed towards the middle region of human ENOX1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5113710

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Antigen:
PCBP3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PCBP3

Gene Alias:
alpha-CP3; AlphaCP-3; Pcbp3; PCBP3OT; PCBP3-OT1; PCBP3-overlapping transcript; PCBP3-overlapping transcript 1; poly(rC) binding protein 3; poly(rC)-binding protein 3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54039

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
P57721

Gene Symbols:
PCBP3

Immunogen:
Synthetic peptide directed towards the middle region of human PCBP3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG