PIPA511379
Bcl-2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA511379-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA511379 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
Bcl-2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Bcl2
Gene Alias
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
596
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
2.0 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P10415
Gene Symbols
Bcl2
Immunogen
KLH conjugated synthetic peptide between 75-110 amino acids from human Bcl
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with bovine based on sequence homology
- BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
- The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
- Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
- Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
- Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
- Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
- In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
- Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
- The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.
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Antigen: Bcl-2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Bcl2
Gene Alias: apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 596
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.0 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P10415
Gene Symbols: Bcl2
Immunogen: KLH conjugated synthetic peptide between 75-110 amino acids from human Bcl
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Bcl-2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Bcl2
Gene Alias:
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
596
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.0 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P10415
Gene Symbols:
Bcl2
Immunogen:
KLH conjugated synthetic peptide between 75-110 amino acids from human Bcl
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: GPR177
Classification: Polyclonal
Conjugate: Unconjugated
Gene: WLS
Gene Alias: 5031439A09Rik; AI173978; AI987742; C1orf139; evenness interrupted homolog; EVI; G protein-coupled receptor 177; Gpr177; Integral membrane protein GPR177; mig-14; MRP; Protein evenness interrupted homolog; protein wntless homolog; Putative NF-kappa-B-activating protein 373; putative NFkB activating protein 373; UNQ85/PRO18667; WLS; Wnt ligand secretion mediator; wntless homolog; wntless homolog (Drosophila); wntless Wnt ligand secretion mediator
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 79971
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.: Q5T9L3
Gene Symbols: WLS
Immunogen: Synthetic peptide directed towards the middle region of human GPR177
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
GPR177
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
WLS
Gene Alias:
5031439A09Rik; AI173978; AI987742; C1orf139; evenness interrupted homolog; EVI; G protein-coupled receptor 177; Gpr177; Integral membrane protein GPR177; mig-14; MRP; Protein evenness interrupted homolog; protein wntless homolog; Putative NF-kappa-B-activating protein 373; putative NFkB activating protein 373; UNQ85/PRO18667; WLS; Wnt ligand secretion mediator; wntless homolog; wntless homolog (Drosophila); wntless Wnt ligand secretion mediator
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
79971
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.:
Q5T9L3
Gene Symbols:
WLS
Immunogen:
Synthetic peptide directed towards the middle region of human GPR177
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CA095
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STUM
Gene Alias: 6330403A02Rik; C1orf95; ENSMUSG00000056615; Gm10001; LOC689499; Protein stum homolog; R75555; RIKEN cDNA 6330403A02 gene; similar to Y97E10AL.1; Stum; stum, mechanosensory transduction mediator homolog; stumble homolog
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 375057
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.: Q69YW2
Gene Symbols: STUM
Immunogen: Synthetic peptide directed towards the middle region of human C1orf95
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CA095
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STUM
Gene Alias:
6330403A02Rik; C1orf95; ENSMUSG00000056615; Gm10001; LOC689499; Protein stum homolog; R75555; RIKEN cDNA 6330403A02 gene; similar to Y97E10AL.1; Stum; stum, mechanosensory transduction mediator homolog; stumble homolog
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
375057
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.:
Q69YW2
Gene Symbols:
STUM
Immunogen:
Synthetic peptide directed towards the middle region of human C1orf95
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MXRA7
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MXRA7
Gene Alias: 1810057P16Rik; E130302J09Rik; HBV PreS1-transactivated protein 1; matrix remodeling associated 7; matrix remodelling associated 7; matrix-remodeling-associated protein 7; matrix-remodelling associated 7; Mxra7; PS1TP1; TMAP1; transmembrane anchor protein 1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 439921
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.: P84157
Gene Symbols: MXRA7
Immunogen: Synthetic peptide directed towards the N terminal region of human MXRA7
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MXRA7
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MXRA7
Gene Alias:
1810057P16Rik; E130302J09Rik; HBV PreS1-transactivated protein 1; matrix remodeling associated 7; matrix remodelling associated 7; matrix-remodeling-associated protein 7; matrix-remodelling associated 7; Mxra7; PS1TP1; TMAP1; transmembrane anchor protein 1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
439921
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.:
P84157
Gene Symbols:
MXRA7
Immunogen:
Synthetic peptide directed towards the N terminal region of human MXRA7
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG