PIPA511389
MCL-1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA511389-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA511389 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
MCL-1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MCL1
Gene Alias
AW556805; BCL2 family apoptosis regulator; BCL2L3; bcl2-L-3; Bcl-2-like protein 3; bcl-2-related protein EAT/mcl1; EAT; Induced myeloid leukemia cell differentiation protein Mcl-1; induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Mcl1; Mcl-1; mcl1/EAT; MCL1-ES; MCL1L; MCL1S; MCL-1S; MGC104264; MGC1839; myeloid cell leukemia 1; myeloid cell leukemia ES; myeloid cell leukemia sequence 1; myeloid cell leukemia sequence 1 (BCL2-related); TM
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
17210, 4170
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P97287, Q07820
Gene Symbols
MCL1
Immunogen
KLH conjugated synthetic peptide between 191-226 amino acids from human MCL1
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description MCL1 (Myeloid cell leukemia-1) belongs to the Bcl-2 family and is involved in programing, differentiation and concomitant maintenance of cell viability, but not of proliferation
- Isoform 1 of MCL1 inhibits apoptosis while isoform 2 promotes it
- The carboxy terminal of MCL1 and bcl-2 share significant sequence homology
- Expression of MCL1 is increased upon exposure of ML-1 cells to various types of DNA damaging agents (e.g
- ionizing radiation, μgtraviolet radiation, and alkylating drugs) along with increases in GADD45 and Bax and a decrease in bcl-2
- Enhanced expression of MCL1, prominently associated with mitochondria, complements the continued expression of bcl-2 in ML-1 cells undergoing differentiation
- Like bcl-2, MCL1 has the capacity to promote cell viability under conditions that otherwise cause apoptosis
- While the mechanism by which MCL1 inhibits apoptosis is not known, it is thought that it may heterodimerize and neutralize pro-apoptotic members of the Bcl-2 family such as Bim or Bak
- MCL1 was originally identified in differentiating myeloid cells, but has since been shown to be expressed in multiple cell types
- MCL1 is essential for embryogenesis and for the development and maintenance of B and T lymphocytes in animals
- MCL1 exists as at least two distinct isoforms designated MCL1L and MCL1S
- In marked contrast to the larger isoform of MCL1, overexpression of MCL1S promotes cell death.
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Antigen: MCL-1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MCL1
Gene Alias: AW556805; BCL2 family apoptosis regulator; BCL2L3; bcl2-L-3; Bcl-2-like protein 3; bcl-2-related protein EAT/mcl1; EAT; Induced myeloid leukemia cell differentiation protein Mcl-1; induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Mcl1; Mcl-1; mcl1/EAT; MCL1-ES; MCL1L; MCL1S; MCL-1S; MGC104264; MGC1839; myeloid cell leukemia 1; myeloid cell leukemia ES; myeloid cell leukemia sequence 1; myeloid cell leukemia sequence 1 (BCL2-related); TM
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 17210, 4170
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P97287, Q07820
Gene Symbols: MCL1
Immunogen: KLH conjugated synthetic peptide between 191-226 amino acids from human MCL1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MCL-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MCL1
Gene Alias:
AW556805; BCL2 family apoptosis regulator; BCL2L3; bcl2-L-3; Bcl-2-like protein 3; bcl-2-related protein EAT/mcl1; EAT; Induced myeloid leukemia cell differentiation protein Mcl-1; induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Mcl1; Mcl-1; mcl1/EAT; MCL1-ES; MCL1L; MCL1S; MCL-1S; MGC104264; MGC1839; myeloid cell leukemia 1; myeloid cell leukemia ES; myeloid cell leukemia sequence 1; myeloid cell leukemia sequence 1 (BCL2-related); TM
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
17210, 4170
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P97287, Q07820
Gene Symbols:
MCL1
Immunogen:
KLH conjugated synthetic peptide between 191-226 amino acids from human MCL1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: TMTC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Tmtc1
Gene Alias: Arg99; ARG99 homolog; BC023818; OLF; Protein O-mannosyl-transferase TMTC1; Tmtc1; TMTC1A; transmembrane and tetratricopeptide repeat containing 1; transmembrane and tetratricopeptide repeat containing 1A; transmembrane and TPR repeat-containing protein 1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 83857
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.: Q8IUR5
Gene Symbols: Tmtc1
Immunogen: Synthetic peptide directed towards the middle region of human TMTC1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TMTC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Tmtc1
Gene Alias:
Arg99; ARG99 homolog; BC023818; OLF; Protein O-mannosyl-transferase TMTC1; Tmtc1; TMTC1A; transmembrane and tetratricopeptide repeat containing 1; transmembrane and tetratricopeptide repeat containing 1A; transmembrane and TPR repeat-containing protein 1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
83857
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.:
Q8IUR5
Gene Symbols:
Tmtc1
Immunogen:
Synthetic peptide directed towards the middle region of human TMTC1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TMTC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Tmtc1
Gene Alias: Arg99; ARG99 homolog; BC023818; OLF; Protein O-mannosyl-transferase TMTC1; Tmtc1; TMTC1A; transmembrane and tetratricopeptide repeat containing 1; transmembrane and tetratricopeptide repeat containing 1A; transmembrane and TPR repeat-containing protein 1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 83857
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.: Q8IUR5
Gene Symbols: Tmtc1
Immunogen: Synthetic peptide directed towards the middle region of human TMTC1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TMTC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Tmtc1
Gene Alias:
Arg99; ARG99 homolog; BC023818; OLF; Protein O-mannosyl-transferase TMTC1; Tmtc1; TMTC1A; transmembrane and tetratricopeptide repeat containing 1; transmembrane and tetratricopeptide repeat containing 1A; transmembrane and TPR repeat-containing protein 1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
83857
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.:
Q8IUR5
Gene Symbols:
Tmtc1
Immunogen:
Synthetic peptide directed towards the middle region of human TMTC1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SULT1C2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SULT1C2
Gene Alias: (PST)G; 1810008N17Rik; 1C member 4; HAST-I; humSULTC2; LOC100729651; MGC149521; MGC34422; mOLFST; N-hydroxyarylamine sulfotransferase; N-hydroxylarylamine sulfotransferase; phenol sulfotransferase; Phenol sulfotransferase 1c1; P-SULT; rabSULT1C2; rSULT1C2; St1c1; ST1C2; ST1C4; Stp2; sulfotransferase; sulfotransferase 1C1; Sulfotransferase 1C2; sulfotransferase 1C4; sulfotransferase family 1A phenol-preferring member 2; sulfotransferase family 1A, member 2; sulfotransferase family 1A, phenol-preferring, member 2; sulfotransferase family 1C member 2; sulfotransferase family 1C member 4; sulfotransferase family, cytosolic, 1C, member 1; sulfotransferase family, cytosolic, 1C, member 2; sulfotransferase family, cytosolic, 1C, member 3; sulfotransferase family, cytosolic, 1C, member 4; sulfotransferase family, cytosolic, 1C, member C2; sulfotransferase K1; sulfotransferase, phenol preferring 2; sulphotransferase family cytosolic 1A phenol-preferring member 2; Sult1a2; SULT1C; SULT1C#1;
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6819
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.: O00338
Gene Symbols: SULT1C2
Immunogen: Synthetic peptide directed towards the C terminal region of human SULT1C2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SULT1C2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SULT1C2
Gene Alias:
(PST)G; 1810008N17Rik; 1C member 4; HAST-I; humSULTC2; LOC100729651; MGC149521; MGC34422; mOLFST; N-hydroxyarylamine sulfotransferase; N-hydroxylarylamine sulfotransferase; phenol sulfotransferase; Phenol sulfotransferase 1c1; P-SULT; rabSULT1C2; rSULT1C2; St1c1; ST1C2; ST1C4; Stp2; sulfotransferase; sulfotransferase 1C1; Sulfotransferase 1C2; sulfotransferase 1C4; sulfotransferase family 1A phenol-preferring member 2; sulfotransferase family 1A, member 2; sulfotransferase family 1A, phenol-preferring, member 2; sulfotransferase family 1C member 2; sulfotransferase family 1C member 4; sulfotransferase family, cytosolic, 1C, member 1; sulfotransferase family, cytosolic, 1C, member 2; sulfotransferase family, cytosolic, 1C, member 3; sulfotransferase family, cytosolic, 1C, member 4; sulfotransferase family, cytosolic, 1C, member C2; sulfotransferase K1; sulfotransferase, phenol preferring 2; sulphotransferase family cytosolic 1A phenol-preferring member 2; Sult1a2; SULT1C; SULT1C#1;
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6819
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.:
O00338
Gene Symbols:
SULT1C2
Immunogen:
Synthetic peptide directed towards the C terminal region of human SULT1C2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG