PIPA511397

PUMA alpha Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA511397-Each-of-1 In Stock ₹ 46,929.66

PIPA511397 - Each of 1

₹ 46,929.66

In Stock

Quantity

1

Base Price: ₹ 46,929.66

GST (18%): ₹ 8,447.339

Total Price: ₹ 55,376.999

Antigen

PUMA alpha

Classification

Polyclonal

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q96PG8, Q9BXH1

Gene Symbols

BBC3

Immunogen

KLH conjugated synthetic peptide between 119-154 amino acids from human Puma BH3 Domain

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Gene

BBC3

Gene Alias

BBC3; BCL2 binding component 3; Bcl-2 binding component 3; bcl-2-binding component 3; Bcl-2-binding component 3, isoforms 1/2; Bcl-2-binding component 3, isoforms 3/4; BH3-only; FLJ42994; JFY1; JFY-1; p53 up-regulated modulator of apoptosis; PUMA; PUMA/JFY1

Host Species

Rabbit

Purification Method

Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status

RUO

Gene ID (Entrez)

27113

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Description

  • This antibody is predicted to react with mouse and rat based on sequence homology
  • PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53
  • The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b
  • PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53
  • PUMA may be a direct mediator of p53-induced apoptosis
  • Antisense inhibition of PUMA expression reduced the apoptotic response to p53, and PUMA is likely to play a role in mediating p53-induced cell death through the cytochrome c/Apaf-1-dependent pathway.

Compare Similar Items

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Img

Thermo Scientific

PIPA511397

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Antigen:
PUMA alpha

Classification:
Polyclonal

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q96PG8, Q9BXH1

Gene Symbols:
BBC3

Immunogen:
KLH conjugated synthetic peptide between 119-154 amino acids from human Puma BH3 Domain

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Gene:
BBC3

Gene Alias:
BBC3; BCL2 binding component 3; Bcl-2 binding component 3; bcl-2-binding component 3; Bcl-2-binding component 3, isoforms 1/2; Bcl-2-binding component 3, isoforms 3/4; BH3-only; FLJ42994; JFY1; JFY-1; p53 up-regulated modulator of apoptosis; PUMA; PUMA/JFY1

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status:
RUO

Gene ID (Entrez):
27113

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIPA5113970

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Antigen:
GALM

Classification:
Polyclonal

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q96C23

Gene Symbols:
GALM

Immunogen:
Synthetic peptide directed towards the N terminal region of human GALM

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
GALM

Gene Alias:
A530057M15Rik; aldose 1-epimerase; aldose mutarotase; AU015645; AU020959; BLOCK25; epididymis secretory sperm binding protein Li 63p; galactomutarotase; galactose enzyme activator; galactose mutarotase; galactose mutarotase (aldose 1-epimerase); GALM; GLAT; HEL-S-63p; IBD1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
130589

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIPA5113971

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Antigen:
LRRC28

Classification:
Polyclonal

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q86X40

Gene Symbols:
LRRC28

Immunogen:
Synthetic peptide directed towards the N terminal region of human LRRC28

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
LRRC28

Gene Alias:
1300004K21Rik; 2210012C09Rik; 2310058O11Rik; leucine rich repeat containing 28; leucine-rich repeat-containing protein 28; LRRC28; UNQ436/PRO867

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
123355

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIPA5113972

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Antigen:
FAM76B

Classification:
Polyclonal

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q5HYJ3

Gene Symbols:
Fam76b

Immunogen:
Synthetic peptide directed towards the middle region of human FAM76B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
Fam76b

Gene Alias:
2810485I05Rik; C78303; FAM76B; family with sequence similarity 76 member B; family with sequence similarity 76, member B; protein FAM76B; RGD1311077

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
143684

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid