PIPA5113986
SDE2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5113986-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5113986 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
SDE2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SDE2
Gene Alias
C1orf55; dJ671D7.1; FLJ35382; protein SDE2 homolog; Replication stress response regulator SDE2; RGD1305572; SDE2; SDE2 telomere maintenance homolog; SDE2 telomere maintenance homolog (S. pombe); UPF0667 protein C1orf55; UPF0667 protein C1orf55 homolog
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
163859
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.
Q6IQ49
Gene Symbols
SDE2
Immunogen
Synthetic peptide directed towards the C terminal region of human C1orf55
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Immunogen sequence: AFTSVAELEL LGLEKLKCEL MALGLKCGGT LQERAARLFS VRGLAKEQID For short term use, store at 2-8°C up to 1 week
- For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles
- Predicted homology: Cow: 100%; Dog: 100%; Goat: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 100%; Zebrafish: 100% Involved in both DNA replication and cell cycle control (PubMed:27906959)
- Unprocessed SDE2 interacts with PCNA via its PIP-box
- The interaction with PCNA prevents monoubiquitination of the latter thereby inhibiting translesion DNA synthesis
- The binding of SDE2 to PCNA also leads to processing of SDE2 by an unidentified deubiquitinating enzyme, cleaving off the N-terminal ubiquitin-like domain
- The resulting mature SDE2 is degraded by the DCX(DTL) complex in a cell cycle- and DNA damage dependent manner (PubMed:27906959)
- Binding of SDE2 to PCNA is necessary to counteract damage due to μgtraviolet light induced replication stress
- The complete degradation of SDE2 is necessary to allow S-phase progression (PubMed:27906959)
- [UniProt]
Compare Similar Items
Show Difference
Antigen: SDE2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SDE2
Gene Alias: C1orf55; dJ671D7.1; FLJ35382; protein SDE2 homolog; Replication stress response regulator SDE2; RGD1305572; SDE2; SDE2 telomere maintenance homolog; SDE2 telomere maintenance homolog (S. pombe); UPF0667 protein C1orf55; UPF0667 protein C1orf55 homolog
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 163859
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.: Q6IQ49
Gene Symbols: SDE2
Immunogen: Synthetic peptide directed towards the C terminal region of human C1orf55
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SDE2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SDE2
Gene Alias:
C1orf55; dJ671D7.1; FLJ35382; protein SDE2 homolog; Replication stress response regulator SDE2; RGD1305572; SDE2; SDE2 telomere maintenance homolog; SDE2 telomere maintenance homolog (S. pombe); UPF0667 protein C1orf55; UPF0667 protein C1orf55 homolog
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
163859
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.:
Q6IQ49
Gene Symbols:
SDE2
Immunogen:
Synthetic peptide directed towards the C terminal region of human C1orf55
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SGMS2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SGMS2
Gene Alias: 4933405A16Rik; 5133401H06Rik; AI854299; MGC26963; phosphatidylcholine:ceramide cholinephosphotransferase 2; RGD1305778; SGMS2; SM synthase; SMS2; spermatin; Sphingomyelin synthase 2
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 166929
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.: Q8NHU3
Gene Symbols: SGMS2
Immunogen: Synthetic peptide directed towards the N terminal region of human SGMS2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SGMS2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SGMS2
Gene Alias:
4933405A16Rik; 5133401H06Rik; AI854299; MGC26963; phosphatidylcholine:ceramide cholinephosphotransferase 2; RGD1305778; SGMS2; SM synthase; SMS2; spermatin; Sphingomyelin synthase 2
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
166929
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.:
Q8NHU3
Gene Symbols:
SGMS2
Immunogen:
Synthetic peptide directed towards the N terminal region of human SGMS2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SGMS2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SGMS2
Gene Alias: 4933405A16Rik; 5133401H06Rik; AI854299; MGC26963; phosphatidylcholine:ceramide cholinephosphotransferase 2; RGD1305778; SGMS2; SM synthase; SMS2; spermatin; Sphingomyelin synthase 2
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 166929
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.: Q8NHU3
Gene Symbols: SGMS2
Immunogen: Synthetic peptide directed towards the N terminal region of human SGMS2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SGMS2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SGMS2
Gene Alias:
4933405A16Rik; 5133401H06Rik; AI854299; MGC26963; phosphatidylcholine:ceramide cholinephosphotransferase 2; RGD1305778; SGMS2; SM synthase; SMS2; spermatin; Sphingomyelin synthase 2
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
166929
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.:
Q8NHU3
Gene Symbols:
SGMS2
Immunogen:
Synthetic peptide directed towards the N terminal region of human SGMS2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: FAM76A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Fam76a
Gene Alias: Fam76a; family with sequence similarity 76 member A; family with sequence similarity 76, member A; protein FAM76A; RGD1305162
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 199870
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.: Q8TAV0
Gene Symbols: Fam76a
Immunogen: Synthetic peptide directed towards the N terminal region of human FAM76A
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
FAM76A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Fam76a
Gene Alias:
Fam76a; family with sequence similarity 76 member A; family with sequence similarity 76, member A; protein FAM76A; RGD1305162
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
199870
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.:
Q8TAV0
Gene Symbols:
Fam76a
Immunogen:
Synthetic peptide directed towards the N terminal region of human FAM76A
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG