PIPA5114027

ALAS1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114027-Each-of-1 In Stock ₹ 43,592.82

PIPA5114027 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

ALAS1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ALAS1

Gene Alias

5'-aminolevulinate synthase 1; 5-aminolevulinate synthase 1; 5-aminolevulinate synthase, nonspecific, mitochondrial; 5-aminolevulinic acid synthase 1; ALAS; ALA-S; ALAS1; Alas-1; ALAS3; ALASH; Alas-h; ALAS-N; aminolevulinate synthase H; aminolevulinate, delta-, synthase 1; aminolevulinic acid synthase 1; delta-ALA synthase 1; delta-ALA synthetase; delta-aminolevulinate synthase 1; MIG4; migration-inducing protein 4; OK/SW-cl.121; succinyl-CoA: glycine C-succinyl transferase

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

211

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.

P13196

Gene Symbols

ALAS1

Immunogen

Synthetic peptide directed towards the N terminal region of human ALAS1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA554564

--

Img

Thermo Scientific

PIPA588521

--

Img

Thermo Scientific

PIPA597448

--

Img

Thermo Scientific

PIPA545361

--

Img

Thermo Scientific

PIPA571436

--

Img

Thermo Scientific

PIPA5114249

--

Img

Thermo Scientific

PIPA570861

--

Img

Thermo Scientific

PIPA559335

--

Description

  • Immunogen sequence: ETSAGPSVVS VKTDGGDPSG LLKNFQDIMQ KQRPERVSHL LQDNLPKSVS For short term use, store at 2-8°C up to 1 week
  • For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles
  • Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 93%; Zebrafish: 86% ALAS-1 is a nuclear-encoded mitochondrial matrix enzyme which catalyzes the condensation of glycine with succinyl-CoA to form delta-amino levulinate, CO2 and CoA
  • It regulates the first and rate-limiting step of heme biosynthetic pathway
  • It is one of the two isoforms of ALAS and is a pyridoxal-5' phosphate dependant housekeeping enzyme
  • It is ubiquitously expressed and is responsible of providing heme for cytochromes and other hemoproteins
  • ALAS1 in liver undergoes negative feedback regulation by heme
  • Transcription of ALAS1 gene is stimulated by cAMP and respiratory uncoupling whereas Phorbol esters and insulin repress ALAS1 gene expression
  • ALAS1 is suggested to be involved in reciprocal regulation of Heme biosynthesis and circadian clock suggesting a potential target for treatment of circadian disorders
  • ALAS1 gene expression is down regulated in Acute Liver failure resulting in altered heme metabolism and liver function.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5114027

--


Antigen:
ALAS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ALAS1

Gene Alias:
5'-aminolevulinate synthase 1; 5-aminolevulinate synthase 1; 5-aminolevulinate synthase, nonspecific, mitochondrial; 5-aminolevulinic acid synthase 1; ALAS; ALA-S; ALAS1; Alas-1; ALAS3; ALASH; Alas-h; ALAS-N; aminolevulinate synthase H; aminolevulinate, delta-, synthase 1; aminolevulinic acid synthase 1; delta-ALA synthase 1; delta-ALA synthetase; delta-aminolevulinate synthase 1; MIG4; migration-inducing protein 4; OK/SW-cl.121; succinyl-CoA: glycine C-succinyl transferase

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
211

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
P13196

Gene Symbols:
ALAS1

Immunogen:
Synthetic peptide directed towards the N terminal region of human ALAS1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114030

--


Antigen:
KCTD21

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KCTD21

Gene Alias:
BTB/POZ domain-containing protein KCTD21; EG622320; K+ channel tetramerisation/BTB/POZ/BTB domain profile containing protein; KCASH2; KCASH2 protein; KCTD21; potassium channel tetramerisation domain containing 21; potassium channel tetramerization domain containing 21; Potassium channel tetramerization domain-containing protein 21

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
283219

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q4G0X4

Gene Symbols:
KCTD21

Immunogen:
Synthetic peptide directed towards the N terminal region of human KCTD21

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114031

--


Antigen:
MPEG1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mpeg1

Gene Alias:
macrophage expressed 1; macrophage expressed gene 1; macrophage gene 1 protein; Macrophage-expressed gene 1 protein; MGC150002; MGC150003; MPEG1; MPG1; Mpg-1; MPS1; P-2; perforin 2; Perforin-2; Protein MPS1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
219972

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q2M385

Gene Symbols:
Mpeg1

Immunogen:
Synthetic peptide directed towards the middle region of human MPEG1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114033

--


Antigen:
ApoA2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APOA2

Gene Alias:
Alp-2; APO A2; APOA2; Apoa-2; ApoAII; Apo-AII; ApoA-II; Apolipoprotein; Apolipoprotein A2; Apolipoprotein AII; apolipoprotein A-II; Apolipoprotein A-II(1-76); Hdl-1; ProapoA-II; Proapolipoprotein A-II; Truncated apolipoprotein A-II

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
336

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
P02652

Gene Symbols:
APOA2

Immunogen:
Synthetic peptide directed towards the N terminal region of human APOA2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG