PIPA5114147

RWDD3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5114147-Each-of-1 In Stock ₹ 44,705.10

PIPA5114147 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

RWDD3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RWDD3

Gene Alias

2510027J23Rik; 3110037C01Rik; AI035684; AI662458; pituitary tumor X2CR1 protein; RSUME; RWD domain containing 3; RWD domain-containing protein 3; RWD domain-containing sumoylation enhancer; RWD-containing sumoylation enhancer; Rwdd3; X2cr1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

25950

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.

Q9Y3V2

Gene Symbols

RWDD3

Immunogen

Immunogen sequence: ESLLSEPMVH ELVLWIQQNL RHILSQPETG SGSEKCTFST STTMDDGLWI

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: ESLLSEPMVH ELVLWIQQNL RHILSQPETG SGSEKCTFST STTMDDGLWI For short term use, store at 2-8°C up to 1 week
  • For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles
  • Predicted homology: Dog: 86%; Guinea Pig: 86%; Human: 100%; Mouse: 79%; Rat: 86% RWDD3 (RSUME), a small RWD-containing protein, has a central role in sumoylation by enhancing SUMO conjugation in the regulatory network of immune-inflammatory signals
  • RWDD3 increases Ikappa-Beta sumoylation and stability
  • In addition, RWDD3 inhibits TNF-a-induced kappaB-LUC (Luciferase) reporter activity, showing the functional consequence of Ikappa-Beta increased stability
  • RSUME-enhanced sumoylation of Ikappa-Beta leads to the inhibition of NF-kappa-Beta activity on two well-known inflammatory genes, IL-8 and cyclooxygenase-2 (Cox-2) and therefore may also favor anti-inflammatory pathways
  • Expression of RWDD3 was induced under hypoxic conditions and it has a potential role during vascularization
  • Both BMP-4 and RWDD3 may be interesting targets for inhibiting steps involved in pituitary tumorigenesis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5114147

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Antigen:
RWDD3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RWDD3

Gene Alias:
2510027J23Rik; 3110037C01Rik; AI035684; AI662458; pituitary tumor X2CR1 protein; RSUME; RWD domain containing 3; RWD domain-containing protein 3; RWD domain-containing sumoylation enhancer; RWD-containing sumoylation enhancer; Rwdd3; X2cr1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25950

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q9Y3V2

Gene Symbols:
RWDD3

Immunogen:
Immunogen sequence: ESLLSEPMVH ELVLWIQQNL RHILSQPETG SGSEKCTFST STTMDDGLWI

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114148

--


Antigen:
NPTX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nptx1

Gene Alias:
47 kDa taipoxin-binding protein; D11Bwg1004e; neuronal pentraxin 1; neuronal pentraxin I; Neuronal pentraxin-1; NP1; NP-I; NPTX1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18164

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q62443

Gene Symbols:
Nptx1

Immunogen:
Immunogen sequence: EGKGGPKNDT EERAKIESAL TSLHQRISEL EKGQKDNRPG DKFQLTFPLR

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114149

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Antigen:
SCAMP5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SCAMP5

Gene Alias:
hSCAMP5; Sc5; scamp5; scamp5a; Secretory carrier membrane protein 5; secretory carrier membrane protein 5a; secretory carrier membrane protein 5-like; secretory carrier-associated membrane protein 5; wu:fc30b07; zgc:77438

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56807

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q9JKD3

Gene Symbols:
SCAMP5

Immunogen:
Immunogen sequence: VFSFIALSMV HKFYRGSGGS FSKAQEEWTT GAWKNPHVQQ AAQNAAMGAA

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114150

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Antigen:
GCH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GCH1

Gene Alias:
dystonia 14; DYT14; DYT5; DYT5a; GCH; Gch1; GTP cyclohydrolase 1; GTP cyclohydrolase I; GTPCH; GTP-CH; GTPCH1; GTP-CH-1; GTP-CH-I; guanosine 5'-triphosphate cyclohydrolase I; HPABH4B

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2643

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
P30793

Gene Symbols:
GCH1

Immunogen:
Synthetic peptide directed towards the N-terminal region of Human GCH1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG