PIPA5114363

ATF6 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114363-Each-of-1 In Stock ₹ 44,705.10

PIPA5114363 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

ATF6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ATF6

Gene Alias

9130025P16Rik; 9630036G24; AA617266; AA789574; ACHM7; activating transcription factor 6; activating transcription factor 6 alpha; Activating transcription factor 6 beta; ATF 6; Atf6; ATF6 alpha; ATF6A; Atf6alpha; ATF6-alpha; Atf6b; ATF6beta; ATF6-beta; cAMP response element binding protein-related protein; cAMP response element-binding protein-related protein; cAMP responsive element binding protein-like 1; cAMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; Crebl1; Creb-related protein; CREB-RP; Cyclic AMP-dependent transcription factor ATF-6 alpha; cyclic AMP-dependent transcription factor ATF-6 beta; DKFZp686P2194; ESTM49; FLJ21663; G13; Processed cyclic AMP-dependent transcription factor ATF-6 alpha; Processed cyclic AMP-dependent transcription factor ATF-6 beta; Protein G13

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12915, 1388, 226641, 22926, 304962, 406169

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.

F6VAN0, G3V909, O35451, P18850, Q99941

Gene Symbols

ATF6, ATF6B

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human ATF6 (597-629aa AININENVINGQDYEVMMQIDCQVMDTRILHIK).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • ATF6 is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes
  • It binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3')
  • Binding to ERSE requires binding of NF-Y to ERSE
  • ATF6 could also be involved in activation of transcription by the serum response factor
  • ATF6 exists as a homodimer and heterodimer with ATF6 beta
  • The dimer interacts with the nuclear transcription factor Y (NF-Y) trimer through direct binding to NF-Y subunit C (NF-YC)
  • It Interacts also with the transcription factors GTF2I, YY1 and SRF
  • Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus
  • The basic domain of ATF6 functions as a nuclear localization signal and the basic leucine-zipper domain is sufficient for association with the NF-Y trimer and binding to ERSE
  • During the unfolded protein response an approximately 50 kDa fragment containing the cytoplasmic transcription factor domain is released by proteolysis
  • The cleavage seems to be performed sequentially by site-1 and site-2 proteases
  • ATF6 is N-glycosylated, phosphorylated in vitro by MAPK14/P38MAPK and belongs to the bZIP family.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5114363

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Antigen:
ATF6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATF6

Gene Alias:
9130025P16Rik; 9630036G24; AA617266; AA789574; ACHM7; activating transcription factor 6; activating transcription factor 6 alpha; Activating transcription factor 6 beta; ATF 6; Atf6; ATF6 alpha; ATF6A; Atf6alpha; ATF6-alpha; Atf6b; ATF6beta; ATF6-beta; cAMP response element binding protein-related protein; cAMP response element-binding protein-related protein; cAMP responsive element binding protein-like 1; cAMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; Crebl1; Creb-related protein; CREB-RP; Cyclic AMP-dependent transcription factor ATF-6 alpha; cyclic AMP-dependent transcription factor ATF-6 beta; DKFZp686P2194; ESTM49; FLJ21663; G13; Processed cyclic AMP-dependent transcription factor ATF-6 alpha; Processed cyclic AMP-dependent transcription factor ATF-6 beta; Protein G13

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12915, 1388, 226641, 22926, 304962, 406169

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
F6VAN0, G3V909, O35451, P18850, Q99941

Gene Symbols:
ATF6, ATF6B

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human ATF6 (597-629aa AININENVINGQDYEVMMQIDCQVMDTRILHIK).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114364

--


Antigen:
Fibrinogen alpha chain

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Fga

Gene Alias:
Ac1873; ENSMUSG00000059807; Fba5e; Fga; Fib; Fib2; Fibrinogen a chain; Fibrinogen alpha; Fibrinogen alpha chain; Fibrinogen a chain; fibrinogen, A alpha polypeptide; fibrinogen, alpha polypeptide; Fibrinogena chain; Fibrinopeptide A

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2243, 361969

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P02671, P06399

Gene Symbols:
Fga

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human FGA (687-727aa RTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGSVLRVE).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114365

--


Antigen:
Tec

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tec

Gene Alias:
cytoplasmic tyrosine kinase, Dscr28C related; MGC126760; MGC126762; PSCTK4; TEC; tec protein tyrosine kinase; tyrosine-protein kinase Tec

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100124696, 21682, 7006, 84492

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P24604, P42680

Gene Symbols:
Tec

Immunogen:
A synthetic peptide corresponding to a sequence of human Tec (HDANTLYIFAPSPQSRDLWVKKLKEEIKNNNNIMIKYHPK).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114366

--


Antigen:
MTR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MTR

Gene Alias:
5-methyltetrahydrofolate-homocysteine methyltransferase; 5-methyltetrahydrofolate--homocysteine methyltransferase; 5-methyltetrahydrofolate-homocysteine methyltransferase 1; AI894170; cblG; cobalamin-dependent methionine synthase; D830038K18Rik; FLJ33168; FLJ43216; FLJ45386; HMAG; methionine synthase; Methionine synthase-like protein; methioninesynthase; MS; MTR; Vitamin-B12 dependent methionine synthase

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
238505, 4548, 81522

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
A6H5Y3, Q99707, Q9Z2Q4

Gene Symbols:
MTR

Immunogen:
E.coli-derived human MTR recombinant protein (Position: V880-D1095).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG