PIPA5114386

SKA2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114386-Each-of-1 In Stock ₹ 44,705.10

PIPA5114386 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SKA2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SKA2

Gene Alias

1110001A07Rik; C78640; FAM33A; family with sequence similarity 33, member A; Protein FAM33A; RGD1307084; Ska2; spindle and kinetochore associated complex subunit 2; spindle and kinetochore-associated protein 2; spindle and KT (kinetochore) associated 2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

348235

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Applications

Flow Cytometry, Western Blot

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.

Q8WVK7

Gene Symbols

SKA2

Immunogen

A synthetic peptide corresponding to a sequence of human SKA2 (EAEVDKLELMFQKAESDLDYIQYRLEYEIK).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5114439

--

Img

Thermo Scientific

PIPA5114394

--

Img

Thermo Scientific

PIPA5114371

--

Img

Thermo Scientific

PIPA5114403

--

Img

Thermo Scientific

PIPA5114390

--

Img

Thermo Scientific

PIPA5114379

--

Img

Thermo Scientific

PIPA5114343

--

Img

Thermo Scientific

PIPA5114383

--

Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • Upon entry into mitosis, the cell’s microtubule (MT) network forms the mitotic spindle, allowing the segregation of paired chromosomes
  • Proteinaceous structures on centromeric chromatin termed kinetochores (KT) are essential for the proper attachment of the chromosomes to the spindle MTs
  • A recently discovered spindle and kinetochore complex, comprised of proteins SKA1, SKA2, and SKA3, has been found to be required for stable KT-MT interactions and timely anaphase onset
  • Depletion of either SKA1 or SKA2 by siRNA results in the loss of both proteins from the KT, but does not impact overall KT structure
  • Cells depleted of the SKA complex undergo a prolonged checkpoint-dependent delay in a metaphase-like state, indicating the importance of the SKA complex in the maintenance of the metaphase plate and spindle checkpoint silencing
  • SKA2 has also been shown to interact with glucocorticoid receptors and to be involved in glucocorticoid signaling and cell proliferation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5114386

--


Antigen:
SKA2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SKA2

Gene Alias:
1110001A07Rik; C78640; FAM33A; family with sequence similarity 33, member A; Protein FAM33A; RGD1307084; Ska2; spindle and kinetochore associated complex subunit 2; spindle and kinetochore-associated protein 2; spindle and KT (kinetochore) associated 2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
348235

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Flow Cytometry, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
Q8WVK7

Gene Symbols:
SKA2

Immunogen:
A synthetic peptide corresponding to a sequence of human SKA2 (EAEVDKLELMFQKAESDLDYIQYRLEYEIK).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114387

--


Antigen:
SEMA3B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SEMA3B

Gene Alias:
LUCA-1; Seam V antibody; SemA; sema A; sema A(V); sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; Sema V; SEMA3B; SEMA5; SEMAA; semaphorin 3B; semaphorin A; semaphorin-3B; semaphorin-A; semaphorin-V; semaV

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20347, 363142, 7869

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
Q13214, Q62177

Gene Symbols:
SEMA3B

Immunogen:
E.coli-derived human Semaphorin 3B/SEMA3B recombinant protein (Position: Y55-R624).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114390

--


Antigen:
IL-31

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Il31

Gene Alias:
1700013B14Rik; IL31; IL-31; ILN; Interleukin; interleukin 31; interleukin-31

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
386653, 690028, 76399

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
Q6EAL8, Q6EBC2

Gene Symbols:
Il31

Immunogen:
E.coli-derived human IL-31 recombinant protein (Position: S24-T164).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114391

--


Antigen:
LMTK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LMTK3

Gene Alias:
Aatyk3; Apoptosis-associated tyrosine kinase 3; BC059845; KIAA1883; Lemur tyrosine kinase 3; LMR3; Lmtk3; LOC691056; PPP1R101; protein phosphatase 1, regulatory subunit 101; serine/threonine-protein kinase LMTK3; similar to 5E5 antigen; TYKLM3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114783, 381983, 691056

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
Q5XJV6, Q96Q04

Gene Symbols:
LMTK3

Immunogen:
E.coli-derived human LMTK3 recombinant protein (Position: S1317-D1382).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG