PIPA5114612
Phospho-NPM1 (Ser125) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5114612-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5114612 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Phospho-NPM1 (Ser125)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NPM1
Gene Alias
B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18148, 25498, 4869
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
P06748, P13084, Q61937
Gene Symbols
NPM1
Immunogen
A synthesized peptide derived from human Nucleophosmin around the phosphorylation site of Ser125.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of Nucleophosmin only when phosphorylated at Ser125
- NPM1 (Nucleophosmin 1, B23, nutramin, NO38) is a ubiquitously expressed phosphoprotein involved in ribosome assembly/transport, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication, and regulation of p53
- NPM1 continuously shuttles between the nucleus, cytoplasm, nucleolus and chaperoning core histones from the nucleus to the cytoplasm
- NPM1 has been shown to bind nucleic acid, prevent protein aggregation via its chaperon activities, protect enzymes during thermal denaturation, and facilitate renaturation of chemically denatured proteins
- In its cellular structure role, there is evidence suggesting NPM1 is associated with the centrosome, and is the substrate of CDK2/cyclin E during duplication of centrosomes (cellular division)
- Due to the NPM1 gene interaction with several tumor-associated chromosome translocations, NPM1 is thought to be a portion of several fusion proteins: NPM-ALK, NPM-RAR, and NPM-MLF1
- While it is not thought to be part of the transforming potential of these fusion proteins, NPM1 is believed to act as the interface for oligomerization and oncogenic conversion of these tumor promoting fusion proteins
- Further, NPM1 is also known to sequester the tumor suppressor RF in the nucleolus, protecting it from degradation until it is necessary
- Dysfunction of the NPM1 protein is associated with diseases such as acute myeloid leukemia and lymphomatoid papulosis.
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Antigen: Phospho-NPM1 (Ser125)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NPM1
Gene Alias: B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18148, 25498, 4869
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P06748, P13084, Q61937
Gene Symbols: NPM1
Immunogen: A synthesized peptide derived from human Nucleophosmin around the phosphorylation site of Ser125.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-NPM1 (Ser125)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NPM1
Gene Alias:
B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18148, 25498, 4869
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P06748, P13084, Q61937
Gene Symbols:
NPM1
Immunogen:
A synthesized peptide derived from human Nucleophosmin around the phosphorylation site of Ser125.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-p57 Kip2 (Thr310)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDKN1C
Gene Alias: AL024410; Beckwith Wiedemann syndrome (WBS); BWCR; BWS; CDKI; Cdkn1c; cyclin dependent kinase inhibitor 1C; Cyclin dependent kinase inhibitor 1C (CDKN1C); cyclin-dependent kinase inhibitor 1C; cyclin-dependent kinase inhibitor 1C (P57); cyclin-dependent kinase inhibitor 1C (p57, Kip2); cyclin-dependent kinase inhibitor p57; IMAGE; KIP2; p57; p57 Kip2; p57(kip2); p57KIP2; p57KIP2 A3sh; WBS
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1028
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P49918
Gene Symbols: CDKN1C
Immunogen: A synthesized peptide derived from human p57 Kip2 around the phosphorylation site of Thr310.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-p57 Kip2 (Thr310)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDKN1C
Gene Alias:
AL024410; Beckwith Wiedemann syndrome (WBS); BWCR; BWS; CDKI; Cdkn1c; cyclin dependent kinase inhibitor 1C; Cyclin dependent kinase inhibitor 1C (CDKN1C); cyclin-dependent kinase inhibitor 1C; cyclin-dependent kinase inhibitor 1C (P57); cyclin-dependent kinase inhibitor 1C (p57, Kip2); cyclin-dependent kinase inhibitor p57; IMAGE; KIP2; p57; p57 Kip2; p57(kip2); p57KIP2; p57KIP2 A3sh; WBS
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1028
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P49918
Gene Symbols:
CDKN1C
Immunogen:
A synthesized peptide derived from human p57 Kip2 around the phosphorylation site of Thr310.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-p70 S6 Kinase (Thr252)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RPS6KB1
Gene Alias: 10539; 2610318I15Rik; 4732464A07Rik; 70 kDa ribosomal protein S6 kinase 1; 7084; 70kDa; 7-10; AA959758; AI256796; AI314060; CG10539; CG10539-PA; CG10539-PB; Dmel\CG10539; Dmel_CG10539; Dp70[s6k]; Dp70S6k; dps6k; dS6 kinase; dS6K; d-S6K; dS6K1; EC 2.7.11.1; fs(3)07084; hypothetical protein; kinase p70S6K; KS6B1; l(3)07084; p70 p70-S6K; p70 ribosomal S6 kinase; p70 ribosomal S6 kinase alpha; p70 S6 kinase; p70 S6 kinase 1; p70 S6 kinase alpha; p70 S6 kinase, alpha; p70 S6K; p70 S6KA; p70 S6K-alpha; p70(S6K)-alpha; p70/85s6k; p70/S6K; p70[S6 kinase]; p70[S6k]; p70[S6kinase]; p70-alpha; p70S6 kinase; p70S6k; p70-S6K; p70-S6K 1; p70S6K kinase; p70s6k protein kinase homolog; P70S6K1; p70S6K-alpha; p80-S6K 1; p85 p85S6K; Pk?6; Pk64F; protein kinase-like 64F; PS6K; p-S6K; ribosomal protein S6 kinase; ribosomal protein S6 kinase B1; ribosomal protein S6 kinase beta-1; Ribosomal protein S6 kinase I; ribosomal protein S6 kinase polypeptide 1; ribosomal protein S6 kinase, 70kD, polypeptide 1; ribo
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6198, 72508, 83840
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P23443, P67999, Q8BSK8
Gene Symbols: RPS6KB1
Immunogen: A synthesized peptide derived from human RPS6KB1(Accession P23443), corresponding to amino acid residues around phosphorylated Thr252.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-p70 S6 Kinase (Thr252)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RPS6KB1
Gene Alias:
10539; 2610318I15Rik; 4732464A07Rik; 70 kDa ribosomal protein S6 kinase 1; 7084; 70kDa; 7-10; AA959758; AI256796; AI314060; CG10539; CG10539-PA; CG10539-PB; Dmel\CG10539; Dmel_CG10539; Dp70[s6k]; Dp70S6k; dps6k; dS6 kinase; dS6K; d-S6K; dS6K1; EC 2.7.11.1; fs(3)07084; hypothetical protein; kinase p70S6K; KS6B1; l(3)07084; p70 p70-S6K; p70 ribosomal S6 kinase; p70 ribosomal S6 kinase alpha; p70 S6 kinase; p70 S6 kinase 1; p70 S6 kinase alpha; p70 S6 kinase, alpha; p70 S6K; p70 S6KA; p70 S6K-alpha; p70(S6K)-alpha; p70/85s6k; p70/S6K; p70[S6 kinase]; p70[S6k]; p70[S6kinase]; p70-alpha; p70S6 kinase; p70S6k; p70-S6K; p70-S6K 1; p70S6K kinase; p70s6k protein kinase homolog; P70S6K1; p70S6K-alpha; p80-S6K 1; p85 p85S6K; Pk?6; Pk64F; protein kinase-like 64F; PS6K; p-S6K; ribosomal protein S6 kinase; ribosomal protein S6 kinase B1; ribosomal protein S6 kinase beta-1; Ribosomal protein S6 kinase I; ribosomal protein S6 kinase polypeptide 1; ribosomal protein S6 kinase, 70kD, polypeptide 1; ribo
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6198, 72508, 83840
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P23443, P67999, Q8BSK8
Gene Symbols:
RPS6KB1
Immunogen:
A synthesized peptide derived from human RPS6KB1(Accession P23443), corresponding to amino acid residues around phosphorylated Thr252.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-PAK4/5/6 (Ser474)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PAK4
Gene Alias: 2900083L08Rik; 4732456M09; 5730488L07Rik; 6430627N20; AW555722; KIAA1142; KIAA1264; mKIAA1142; p21 (CDKN1A)-activated kinase 4; p21 (CDKN1A)-activated kinase 6; p21 (CDKN1A)-activated kinase 7; p21 (RAC1) activated kinase 4; p21 (RAC1) activated kinase 5; p21 (RAC1) activated kinase 6; p21 (RAC1) activated kinase 7; p21 protein (Cdc42/Rac)-activated kinase 4; p21 protein (Cdc42/Rac)-activated kinase 6; p21 protein (Cdc42/Rac)-activated kinase 7; p21(CDKN1A)-activated kinase 4; p21(CDKN1A)-activated kinase 6; p21(CDKN1A)-activated kinase 7; p21-activated kinase 4; p21-activated kinase 5; p21-activated kinase 6; p21-activated kinase 7; p21CDKN1A-activated kinase 7; PAK4; PAK-4; PAK5; PAK-5; PAK6; PAK-6; Pak7; PAK-7; protein kinase PAK5; protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs; serine/threonine-protein kinase PAK 4; Serine/threonine-protein kinase PAK 5; serine/threonine-protein kinase PAK 6; serine/threonine-protein kinase PAK 6-like; serine/threonine-protein
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10298, 214230, 292756, 296078, 56924, 57144, 70584
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: O96013, Q3ULB5, Q8BTW9, Q9NQU5, Q9P286
Gene Symbols: PAK4, PAK5, PAK6
Immunogen: A synthesized peptide derived from human PAK4(Accession O96013), corresponding to amino acid residues around phosphorylated Ser474.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-PAK4/5/6 (Ser474)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PAK4
Gene Alias:
2900083L08Rik; 4732456M09; 5730488L07Rik; 6430627N20; AW555722; KIAA1142; KIAA1264; mKIAA1142; p21 (CDKN1A)-activated kinase 4; p21 (CDKN1A)-activated kinase 6; p21 (CDKN1A)-activated kinase 7; p21 (RAC1) activated kinase 4; p21 (RAC1) activated kinase 5; p21 (RAC1) activated kinase 6; p21 (RAC1) activated kinase 7; p21 protein (Cdc42/Rac)-activated kinase 4; p21 protein (Cdc42/Rac)-activated kinase 6; p21 protein (Cdc42/Rac)-activated kinase 7; p21(CDKN1A)-activated kinase 4; p21(CDKN1A)-activated kinase 6; p21(CDKN1A)-activated kinase 7; p21-activated kinase 4; p21-activated kinase 5; p21-activated kinase 6; p21-activated kinase 7; p21CDKN1A-activated kinase 7; PAK4; PAK-4; PAK5; PAK-5; PAK6; PAK-6; Pak7; PAK-7; protein kinase PAK5; protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs; serine/threonine-protein kinase PAK 4; Serine/threonine-protein kinase PAK 5; serine/threonine-protein kinase PAK 6; serine/threonine-protein kinase PAK 6-like; serine/threonine-protein
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10298, 214230, 292756, 296078, 56924, 57144, 70584
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O96013, Q3ULB5, Q8BTW9, Q9NQU5, Q9P286
Gene Symbols:
PAK4, PAK5, PAK6
Immunogen:
A synthesized peptide derived from human PAK4(Accession O96013), corresponding to amino acid residues around phosphorylated Ser474.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG