PIPA5114638
Phospho-RSK Pan (Ser221, Ser227, Ser218, Ser232) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5114638-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5114638 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Phospho-RSK Pan (Ser221, Ser227, Ser218, Ser232)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RPS6KA1
Gene Alias
1110069D02Rik; 2610524K04Rik; 90 kDa ribosomal protein S6 kinase 1; 90 kDa ribosomal protein S6 kinase 2; 90 kDa ribosomal protein S6 kinase 3; 90 kDa ribosomal protein S6 kinase 4; 90 kDa ribosomal protein S6 kinase 6; 90kDa; AI848992; C130006E23; CLS; D17Wsu134e; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1); HU-1; HU-2; HU-3; Insulin-stimulated protein kinase 1; ISPK1; ISPK-1; MAP kinase-activated protein kinase 1a; MAP kinase-activated protein kinase 1b; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1a; MAPK-activated protein kinase 1b; MAPK-activated protein kinase 1c; MAPKAP kinase 1a; MAPKAP kinase 1b; MAPKAP kinase 1c; MAPKAPK1A; MAPKAPK-1a; MAPKAPK1B; MAPKAPK-1b; MAPKAPK1C; MAPKAPK-1c; MAPKAPK1D; mitogen- and stress-activated protein kinase 2; mitogen- and stress-activated protein kinase-2; mitogen-activated protein kinase-activated protein kinase 1C; mMSK2; MPK-9; MRX19; Msk2; Nuclear mitogen- and stress-activated protein kinase 2; p90
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
110651, 117269, 20111, 20112, 27330, 317203, 361715, 501560, 56613, 6195, 6196, 6197, 67071, 81771, 8986
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
O75676, P18653, P18654, P51812, Q15349, Q15418, Q63531, Q7TPS0, Q9UK32, Q9WUT3, Q9Z2B9
Gene Symbols
RPS6KA1, RPS6KA2, Rps6ka3, RPS6KA4, RPS6KA6
Immunogen
A synthesized peptide derived from human RPS6KA1(Accession Q15418), corresponding to amino acid residues around phosphorylated Ser221.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of RSK1/2/3/4 only when phosphorylated at Ser221/227/S218/232
- The p90 ribosomal S6 kinases (RSKs) comprise a family of serine/threonine kinases that lie at the terminus of the ERK pathway
- In humans, the RSK family consists of four isoforms (RSK1 to-4)
- RSK family members are unusual among serine/threonine kinases in that they contain two distinct kinase domains, both of which are catalytically functional
- Theses kinase domains are activated in a sequential manner by a series of phosphorylations
- RSK regulates gene expression via association and phosphorylation of transcriptional regulators including c-Fos, estrogen receptor, NFkappaB/IkappaB alpha, cAMP-response element-binding protein (CREB)
- ERK activates the C-terminal kinase of RSK, leading to activation of the N-terminal kinase
- Members of the RSK family are present in the cytoplasm as well as the nucleus
- Addition of growth factor to the cells results in the activation of both cytosolic and nuclear RSK and the translocation of the cytosolic RSK into the nucleus upon activation
- The activation and nuclear translocation of RSK result in phosphorylation and activation of transcription factors.
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Antigen: Phospho-RSK Pan (Ser221, Ser227, Ser218, Ser232)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RPS6KA1
Gene Alias: 1110069D02Rik; 2610524K04Rik; 90 kDa ribosomal protein S6 kinase 1; 90 kDa ribosomal protein S6 kinase 2; 90 kDa ribosomal protein S6 kinase 3; 90 kDa ribosomal protein S6 kinase 4; 90 kDa ribosomal protein S6 kinase 6; 90kDa; AI848992; C130006E23; CLS; D17Wsu134e; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1); HU-1; HU-2; HU-3; Insulin-stimulated protein kinase 1; ISPK1; ISPK-1; MAP kinase-activated protein kinase 1a; MAP kinase-activated protein kinase 1b; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1a; MAPK-activated protein kinase 1b; MAPK-activated protein kinase 1c; MAPKAP kinase 1a; MAPKAP kinase 1b; MAPKAP kinase 1c; MAPKAPK1A; MAPKAPK-1a; MAPKAPK1B; MAPKAPK-1b; MAPKAPK1C; MAPKAPK-1c; MAPKAPK1D; mitogen- and stress-activated protein kinase 2; mitogen- and stress-activated protein kinase-2; mitogen-activated protein kinase-activated protein kinase 1C; mMSK2; MPK-9; MRX19; Msk2; Nuclear mitogen- and stress-activated protein kinase 2; p90
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 110651, 117269, 20111, 20112, 27330, 317203, 361715, 501560, 56613, 6195, 6196, 6197, 67071, 81771, 8986
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: O75676, P18653, P18654, P51812, Q15349, Q15418, Q63531, Q7TPS0, Q9UK32, Q9WUT3, Q9Z2B9
Gene Symbols: RPS6KA1, RPS6KA2, Rps6ka3, RPS6KA4, RPS6KA6
Immunogen: A synthesized peptide derived from human RPS6KA1(Accession Q15418), corresponding to amino acid residues around phosphorylated Ser221.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-RSK Pan (Ser221, Ser227, Ser218, Ser232)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RPS6KA1
Gene Alias:
1110069D02Rik; 2610524K04Rik; 90 kDa ribosomal protein S6 kinase 1; 90 kDa ribosomal protein S6 kinase 2; 90 kDa ribosomal protein S6 kinase 3; 90 kDa ribosomal protein S6 kinase 4; 90 kDa ribosomal protein S6 kinase 6; 90kDa; AI848992; C130006E23; CLS; D17Wsu134e; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1); HU-1; HU-2; HU-3; Insulin-stimulated protein kinase 1; ISPK1; ISPK-1; MAP kinase-activated protein kinase 1a; MAP kinase-activated protein kinase 1b; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1a; MAPK-activated protein kinase 1b; MAPK-activated protein kinase 1c; MAPKAP kinase 1a; MAPKAP kinase 1b; MAPKAP kinase 1c; MAPKAPK1A; MAPKAPK-1a; MAPKAPK1B; MAPKAPK-1b; MAPKAPK1C; MAPKAPK-1c; MAPKAPK1D; mitogen- and stress-activated protein kinase 2; mitogen- and stress-activated protein kinase-2; mitogen-activated protein kinase-activated protein kinase 1C; mMSK2; MPK-9; MRX19; Msk2; Nuclear mitogen- and stress-activated protein kinase 2; p90
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
110651, 117269, 20111, 20112, 27330, 317203, 361715, 501560, 56613, 6195, 6196, 6197, 67071, 81771, 8986
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O75676, P18653, P18654, P51812, Q15349, Q15418, Q63531, Q7TPS0, Q9UK32, Q9WUT3, Q9Z2B9
Gene Symbols:
RPS6KA1, RPS6KA2, Rps6ka3, RPS6KA4, RPS6KA6
Immunogen:
A synthesized peptide derived from human RPS6KA1(Accession Q15418), corresponding to amino acid residues around phosphorylated Ser221.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-SAMHD1 (Thr592)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SAMHD1
Gene Alias: CHBL2; DCIP; Dendritic cell-derived IFNG-induced protein; deoxynucleoside triphosphate triphosphohydrolase SAMHD1; dNTPase; E330031J07Rik; EGK_02438; HDDC1; hSAMHD1; IFN-gamma induced; interferon-gamma-inducible protein Mg11; Mg11; Mg21; Monocyte protein 5; MOP5; MOP-5; mSAMHD1; RP1-132F21.1; SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1; SAM domain and HD domain 1; SAM domain and HD domain, 1; SAM domain and HD domain-containing protein 1; Samhd1; SBBI88
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 25939, 311580, 56045
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q60710, Q9Y3Z3
Gene Symbols: SAMHD1
Immunogen: A synthesized peptide derived from human SAMHD1 around the phosphorylation site of Thr592.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-SAMHD1 (Thr592)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SAMHD1
Gene Alias:
CHBL2; DCIP; Dendritic cell-derived IFNG-induced protein; deoxynucleoside triphosphate triphosphohydrolase SAMHD1; dNTPase; E330031J07Rik; EGK_02438; HDDC1; hSAMHD1; IFN-gamma induced; interferon-gamma-inducible protein Mg11; Mg11; Mg21; Monocyte protein 5; MOP5; MOP-5; mSAMHD1; RP1-132F21.1; SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1; SAM domain and HD domain 1; SAM domain and HD domain, 1; SAM domain and HD domain-containing protein 1; Samhd1; SBBI88
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
25939, 311580, 56045
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q60710, Q9Y3Z3
Gene Symbols:
SAMHD1
Immunogen:
A synthesized peptide derived from human SAMHD1 around the phosphorylation site of Thr592.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-SGK2 (Thr253)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SGK2
Gene Alias: AI098171; AW146006; dJ138B7.2; H-SGK2; Serine/threonine-protein kinase Sgk2; serum/glucocorticoid regulated kinase 2; serum/glucocorticoid-regulated kinase 2; Sgk2; SGK2, serine/threonine kinase 2; Sgkl
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10110, 171497
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q8R4U9, Q9HBY8
Gene Symbols: SGK2
Immunogen: A synthesized peptide derived from human SGK2 around the phosphorylation site of Thr253.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-SGK2 (Thr253)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SGK2
Gene Alias:
AI098171; AW146006; dJ138B7.2; H-SGK2; Serine/threonine-protein kinase Sgk2; serum/glucocorticoid regulated kinase 2; serum/glucocorticoid-regulated kinase 2; Sgk2; SGK2, serine/threonine kinase 2; Sgkl
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10110, 171497
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q8R4U9, Q9HBY8
Gene Symbols:
SGK2
Immunogen:
A synthesized peptide derived from human SGK2 around the phosphorylation site of Thr253.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-SHP2 (Tyr542)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTPN11
Gene Alias: 2700084A17Rik; AW536184; bptp3; CFC; cSH-PTP2; encodes catalytic domain; HCP; HGNC:9644; JMML; METCDS; MGC14433; Noonan syndrome 1; ns1; null; OTTHUMP00000166108; phosphotyrosyl-protein phosphatase; protein tyrosine phosphatase non-receptor type 11; protein tyrosine phosphatase SH-PTP2; protein tyrosine phosphatase, non-receptor type 11; protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1); protein tyrosine phosphatase, non-receptor type 11 S homeolog; protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C; protein-tyrosine phosphatase SYP; PTP1C; PTP1D; PTP-1D; ptp-2; PTP2C; PTP-2C; Ptpn11; ptpn11.S; ptpn11-a; ptpn11-b; SAP-2; SH2 domain-containing protein tyrosine phosphatase-2; Shp2; shp-2; SHPTP2; SH-PTP2; SH-PTP2 protein tyrosine phosphatase non-receptor type 11; SH-PTP2 protein tyrosine phosphatase, non-receptor type 11; SH-PTP3; Syp; Tyrosine-protein phosphatase non-receptor type 11; XELAEV_18010676mg
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19247, 25622, 5781
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P35235, P41499, Q06124
Gene Symbols: PTPN11
Immunogen: A synthesized peptide derived from human PTPN11(Accession Q06124), corresponding to amino acid residues around phosphorylated Tyr546.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-SHP2 (Tyr542)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTPN11
Gene Alias:
2700084A17Rik; AW536184; bptp3; CFC; cSH-PTP2; encodes catalytic domain; HCP; HGNC:9644; JMML; METCDS; MGC14433; Noonan syndrome 1; ns1; null; OTTHUMP00000166108; phosphotyrosyl-protein phosphatase; protein tyrosine phosphatase non-receptor type 11; protein tyrosine phosphatase SH-PTP2; protein tyrosine phosphatase, non-receptor type 11; protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1); protein tyrosine phosphatase, non-receptor type 11 S homeolog; protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C; protein-tyrosine phosphatase SYP; PTP1C; PTP1D; PTP-1D; ptp-2; PTP2C; PTP-2C; Ptpn11; ptpn11.S; ptpn11-a; ptpn11-b; SAP-2; SH2 domain-containing protein tyrosine phosphatase-2; Shp2; shp-2; SHPTP2; SH-PTP2; SH-PTP2 protein tyrosine phosphatase non-receptor type 11; SH-PTP2 protein tyrosine phosphatase, non-receptor type 11; SH-PTP3; Syp; Tyrosine-protein phosphatase non-receptor type 11; XELAEV_18010676mg
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19247, 25622, 5781
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P35235, P41499, Q06124
Gene Symbols:
PTPN11
Immunogen:
A synthesized peptide derived from human PTPN11(Accession Q06124), corresponding to amino acid residues around phosphorylated Tyr546.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG