PIPA5114689
Caspase 9 (Cleaved Asp315) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5114689-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5114689 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Caspase 9 (Cleaved Asp315)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CASP9
Gene Alias
APAF3; APAF-3; apoptosis-related cysteine protease; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; cas9; CASP9; CASP-9; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase-9; Caspase-9 subunit p10; Caspase-9 subunit p35; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
842
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
P55211
Gene Symbols
CASP9
Immunogen
A synthesized peptide derived from human CASP9(Accession P55211), corresponding to amino acid residues F296-A316.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of fragment of activated Caspase 9 resulting from cleavage adjacent to Asp315
- Caspase 9 (ICE-like apoptotic protease 6, ICE LAP6, apoptotic protease Mch6, apoptotic protease activating factor 3, Apaf3) is a member of the peptidase family C14 that contains a CARD domain
- Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates
- Caspase 9 is active as a heterotetramer, is present in the cytosol and, upon activation, translocates to the mitochondria
- Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6
- Further, Caspase 9 is involved in the activation cascade of caspases responsible for apoptosis execution
- Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3
- Caspase 9 promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner, and proteolytically cleaves poly(ADP- ribose) polymerase (PARP)
- Caspase 9 is expressed in variety of human tissues
- An isoform of rat Caspase-9 has been identified in which the C terminus of full-length Caspase-9 is replaced with an alternative peptide sequence
- Mutations in Caspase 9 affect brain development
- In mice, insufficient Caspase 9 have resulted in abnormal cerebrum development and neuron development
- In humans, dysfunctional Caspase 9 expression vary from tissue to tissue
- Low levels of Caspase 9 may play a role in cancer development and neurodegenerative diseases such as Alzheimer’s Disease (AD).
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Antigen: Caspase 9 (Cleaved Asp315)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CASP9
Gene Alias: APAF3; APAF-3; apoptosis-related cysteine protease; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; cas9; CASP9; CASP-9; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase-9; Caspase-9 subunit p10; Caspase-9 subunit p35; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 842
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P55211
Gene Symbols: CASP9
Immunogen: A synthesized peptide derived from human CASP9(Accession P55211), corresponding to amino acid residues F296-A316.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Caspase 9 (Cleaved Asp315)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CASP9
Gene Alias:
APAF3; APAF-3; apoptosis-related cysteine protease; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; cas9; CASP9; CASP-9; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase-9; Caspase-9 subunit p10; Caspase-9 subunit p35; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
842
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P55211
Gene Symbols:
CASP9
Immunogen:
A synthesized peptide derived from human CASP9(Accession P55211), corresponding to amino acid residues F296-A316.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: H2A.Zac pan-acetyl (K4,K7,K11,K13)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: H2AFZ
Gene Alias: H2A histone family member Z; H2A histone family, member Z; H2A.z; H2a.z-1; H2A/z; H2AFZ; H2az; H2AZ histone; histone H2A.Z
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3015
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P0C0S5
Gene Symbols: H2AFZ
Immunogen: A synthesized peptide derived from human H2AFZ(Accession P0C0S5), corresponding to amino acid residues M1-S21.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
H2A.Zac pan-acetyl (K4,K7,K11,K13)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
H2AFZ
Gene Alias:
H2A histone family member Z; H2A histone family, member Z; H2A.z; H2a.z-1; H2A/z; H2AFZ; H2az; H2AZ histone; histone H2A.Z
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3015
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P0C0S5
Gene Symbols:
H2AFZ
Immunogen:
A synthesized peptide derived from human H2AFZ(Accession P0C0S5), corresponding to amino acid residues M1-S21.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Histone H3ac (pan-acetyl)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: H3C1
Gene Alias: Acetyl H3, Acetyl Histone 3, Acetyl Histone H3, H3, H3 histone family, member A, H3 histone family, member I, H3 histone family, member K, H3 histone family, member M, H3 histone, family 2, H3 histone, family 3A, H3 histone, family 3B, H3 histone, family 3B (H3.3B), H3 histone, family 3C, H3.1-221, H3.1-291, H3.1-I, H3.2, H3.2-221, H3.2-614, H3.2-615, H3.2-616, H3.3A, H3.3b, H3.5, H3/A, H3/i, H3/k, H3/M, H3/n, H3/o, H3-143, H3-291, H3-3A, H3-3B, H3-53, H3-614, H3a, H3b, H3-B, H3c1, H3C10, H3C11, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3c8, H3f, H3-F, H3F1K, H3F2, H3F3, H3F3A, H3f3b, H3F3C, H3FA, H3FB, H3FC HIST1H3C, H3FD, H3FF, H3FH, H3FI, H3FJ, H3FK, H3FL, H3FM, H3FN, H3g, H3h, H3i, Hist1, Hist1h3a, Hist1h3b, Hist1h3c, Hist1h3d, HIST1H3E, Hist1h3f, Hist1h3g, Hist1h3h, Hist1h3i, HIST1H3J, HIST2H3A, Hist2h3b, HIST2H3C, Hist2h3c1, Hist2h3c2, Hist2h3c2-ps, Hist2h3ca1, Hist2h3ca2, HIST2H3D, histone 1, H3a, histone 1, H3f, histone 1, H3h, histone 2, H3a, histone 2, H3c, histone 2, H3c2, histone 2, H3ca2, Histone 3, histone cluster 1, H3a, histone cluster 1, H3f, histone cluster 1, H3h, histone cluster 2, H3a, histone cluster 2, H3c, histone cluster 2, H3c2, histone cluster 2, H3c2, pseudogene, histone gene complex 1, histone H3, histone H3.1, Histone H3.2, histone H3.3, Histone H3.3C, histone H3.5, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l, Histone H3/m, histone H3/o, histone variant H3.5, M32461, pan-acetyl H3K9, H3K14, H3K18, H3K23, H3K27, PP781
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 126961, 260423, 319152, 333932, 360198, 8350, 8357, 8968, 97114
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P68431, P68433, Q71DI3
Gene Symbols: H3C1, H3C10, H3C14, H3C15, H3C7
Immunogen: A synthesized peptide derived from human Histone H3(Accession P68431), corresponding to amino acid residues T4-A25.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Histone H3ac (pan-acetyl)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
H3C1
Gene Alias:
Acetyl H3, Acetyl Histone 3, Acetyl Histone H3, H3, H3 histone family, member A, H3 histone family, member I, H3 histone family, member K, H3 histone family, member M, H3 histone, family 2, H3 histone, family 3A, H3 histone, family 3B, H3 histone, family 3B (H3.3B), H3 histone, family 3C, H3.1-221, H3.1-291, H3.1-I, H3.2, H3.2-221, H3.2-614, H3.2-615, H3.2-616, H3.3A, H3.3b, H3.5, H3/A, H3/i, H3/k, H3/M, H3/n, H3/o, H3-143, H3-291, H3-3A, H3-3B, H3-53, H3-614, H3a, H3b, H3-B, H3c1, H3C10, H3C11, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3c8, H3f, H3-F, H3F1K, H3F2, H3F3, H3F3A, H3f3b, H3F3C, H3FA, H3FB, H3FC HIST1H3C, H3FD, H3FF, H3FH, H3FI, H3FJ, H3FK, H3FL, H3FM, H3FN, H3g, H3h, H3i, Hist1, Hist1h3a, Hist1h3b, Hist1h3c, Hist1h3d, HIST1H3E, Hist1h3f, Hist1h3g, Hist1h3h, Hist1h3i, HIST1H3J, HIST2H3A, Hist2h3b, HIST2H3C, Hist2h3c1, Hist2h3c2, Hist2h3c2-ps, Hist2h3ca1, Hist2h3ca2, HIST2H3D, histone 1, H3a, histone 1, H3f, histone 1, H3h, histone 2, H3a, histone 2, H3c, histone 2, H3c2, histone 2, H3ca2, Histone 3, histone cluster 1, H3a, histone cluster 1, H3f, histone cluster 1, H3h, histone cluster 2, H3a, histone cluster 2, H3c, histone cluster 2, H3c2, histone cluster 2, H3c2, pseudogene, histone gene complex 1, histone H3, histone H3.1, Histone H3.2, histone H3.3, Histone H3.3C, histone H3.5, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l, Histone H3/m, histone H3/o, histone variant H3.5, M32461, pan-acetyl H3K9, H3K14, H3K18, H3K23, H3K27, PP781
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
126961, 260423, 319152, 333932, 360198, 8350, 8357, 8968, 97114
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P68431, P68433, Q71DI3
Gene Symbols:
H3C1, H3C10, H3C14, H3C15, H3C7
Immunogen:
A synthesized peptide derived from human Histone H3(Accession P68431), corresponding to amino acid residues T4-A25.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: H4K12ac
Classification: Polyclonal
Conjugate: Unconjugated
Gene: H4C1
Gene Alias: acetyl Histone H4; Acetyl-H4 K12; Acetyl-H4 Lys12; Acetyl-Histone H4 K12; Acetyl-Histone H4 Lys12; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4 K12ac; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/N; H4/O; H4/p; H4-12; H4-16; H4-53; H4C1; H4C11; H4c12; H4C13; H4c14; H4C15; H4c2; H4c3; H4C4; H4C5; H4c6; H4C8; H4C9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4K12; H4K12a; H4Lys12ac; H4M; HIST1H4; Hist1h4a; HIST1H4B; Hist1h4c; Hist1h4d; HIST1H4E; HIST1H4F; HIST1H4H; Hist1h4i; Hist1h4j; HIST1H4K; HIST1H4L; Hist1h4m; Hist2h4; Hist2h4a; HIST2H4B; HIST4H4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 121504, 319158, 326619, 326620, 8294, 8359, 8363, 8366, 8367, 8370, 97122
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P62805, P62806
Gene Symbols: H4-16, H4C1, H4C11, H4C14, H4C2, H4C5, H4C9
Immunogen: A synthesized peptide derived from human Histone H4(Accession P62805), corresponding to amino acid residues M1-Q28.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
H4K12ac
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
H4C1
Gene Alias:
acetyl Histone H4; Acetyl-H4 K12; Acetyl-H4 Lys12; Acetyl-Histone H4 K12; Acetyl-Histone H4 Lys12; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4 K12ac; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/N; H4/O; H4/p; H4-12; H4-16; H4-53; H4C1; H4C11; H4c12; H4C13; H4c14; H4C15; H4c2; H4c3; H4C4; H4C5; H4c6; H4C8; H4C9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4K12; H4K12a; H4Lys12ac; H4M; HIST1H4; Hist1h4a; HIST1H4B; Hist1h4c; Hist1h4d; HIST1H4E; HIST1H4F; HIST1H4H; Hist1h4i; Hist1h4j; HIST1H4K; HIST1H4L; Hist1h4m; Hist2h4; Hist2h4a; HIST2H4B; HIST4H4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
121504, 319158, 326619, 326620, 8294, 8359, 8363, 8366, 8367, 8370, 97122
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P62805, P62806
Gene Symbols:
H4-16, H4C1, H4C11, H4C14, H4C2, H4C5, H4C9
Immunogen:
A synthesized peptide derived from human Histone H4(Accession P62805), corresponding to amino acid residues M1-Q28.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG