PIPA5114846

Aes Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5114846-Each-of-1 In Stock ₹ 44,705.10

PIPA5114846 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Aes

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AES

Gene Alias

Aes; AES-1; AES-2; AL024115; Amino enhancer of split; amino-terminal enhancer of split; Esp1; gp130-associated protein GAM; Grg; Grg5; Grg-5; Groucho-related protein 5; Protein ESP1; Protein GRG; related to Drosophila groucho; R-esp1; TLE family member 5; TLE family member 5, transcriptional modulator; TLE family member 5; amino-terminal enhancer of split; TLE5

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14797, 166, 29466

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

P63002, P63003, Q08117

Gene Symbols

AES, TLE5

Immunogen

A synthesized peptide derived from human AES(Accession Q08117), corresponding to amino acid residues M1-L43.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total Amino-terminal enhancer of split
  • Adhesion to extracellular matrix regulates cell survival through both integrin engagement and appropriate cell spreading
  • Anoikis is the molecular mechanism of apop-tosis induced by integrin detachment
  • Amino-terminal enhancer of split (AES) is a member of the Groucho/ transducin-like enhancer of split (TLE) family of transcriptional regulators, a group of transcriptional co-repressors that play important roles in neurogenesis, segmentation, and sex determination
  • AES forms a complex with Bit1 (Bcl-2 inhibitor of transcription 1), a mitochondrial protein that is released into the cytoplasm upon onset of apoptosis
  • It has been suggested that this complex turns off a survival-promoting gene transcription program controlled by the TLE protein family
  • Interestingly, apoptosis of cells transfected with AES and Bit1 could be inhibited if the cells were allowed to attach to fibronectin through the alpha5beta1 integrin suggesting that the Bit1-AES pathway contributing to anoikis is regulated by integrins, and in particular, the alpha5beta1 integrin.

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Img

Thermo Scientific

PIPA5114846

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Antigen:
Aes

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AES

Gene Alias:
Aes; AES-1; AES-2; AL024115; Amino enhancer of split; amino-terminal enhancer of split; Esp1; gp130-associated protein GAM; Grg; Grg5; Grg-5; Groucho-related protein 5; Protein ESP1; Protein GRG; related to Drosophila groucho; R-esp1; TLE family member 5; TLE family member 5, transcriptional modulator; TLE family member 5; amino-terminal enhancer of split; TLE5

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14797, 166, 29466

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P63002, P63003, Q08117

Gene Symbols:
AES, TLE5

Immunogen:
A synthesized peptide derived from human AES(Accession Q08117), corresponding to amino acid residues M1-L43.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114847

--


Antigen:
AMPK alpha-1,2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRKAA2

Gene Alias:
2310008I11Rik; 5'-AMP-activated protein kinase alpha-1 catalytic subunit; 5'-AMP-activated protein kinase alpha-2 catalytic subunit; 5'-AMP-activated protein kinase catalytic alpha-2 subunit; 5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase catalytic subunit alpha-2; 5'-AMP-activated protein kinase, catalytic alpha-1 chain; 5'-AMP-activated protein kinase, catalytic alpha-2 chain; 63 kDa subunit; A830082D05; AAPK2; ACACA kinase; acetyl-CoA carboxylase kinase; AI194361; AI450832; AL024255; AMP -activate kinase alpha 1 subunit; AMP-activated protein kinase; AMP-activated protein kinase alpha 2; AMP-activated protein kinase alpha-2 subunit variant 2; AMP-activated protein kinase alpha-2 subunit variant 3; AMP-activated protein kinase alpha-2 variant B; AMP-activated protein kinase, alpha 1 catalytic subunit; AMP-activated protein kinase, catalytic, alpha-1; AMPK; AMPK 63 kDa subunit; AMPK alpha 1; AMPK alpha 2; AMPK alpha-1 chain; AMPK alpha-2 cha

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
105787, 108079, 5562, 5563, 65248, 78975

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P54645, P54646, Q09137, Q13131, Q5EG47, Q8BRK8

Gene Symbols:
PRKAA1, PRKAA2

Immunogen:
A synthesized peptide derived from human PRKAA1(Accession Q13131), corresponding to amino acid residues Y470-S520.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114849

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Antigen:
Angiopoietin 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Angpt1

Gene Alias:
1110046O21Rik; 2810039D03Rik; AGP1; Agpt; Agpt1; ANG1; ang-1; ANG3; ANG-3; angioarrestin; angiopoietin 1; angiopoietin 3; angiopoietin like 1; angiopoietin Y1; angiopoietin-1; Angiopoietin-3; angiopoietin-like 1; angiopoietin-like protein 1; Angiopoietin-related protein 1; Angpt1; ANGPT3; Angptl1; AngY; ARP1; dJ595C2.2; dJ595C2.2 (angiopoietin Y1); endothelial growth factor; KIAA0003; PSEC0154; tie2 receptor ligand; UNQ162; UNQ162/PRO188

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11600, 284, 89807

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O08538, O35460, Q15389

Gene Symbols:
Angpt1

Immunogen:
A synthesized peptide derived from human ANGPT1(Accession Q15389), corresponding to amino acid residues I187-L237.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114850

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Antigen:
ANGPTL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ANGPTL2

Gene Alias:
AI593246; angiopoietin like 2; angiopoietin related protein 2; angiopoietin-like 2; angiopoietin-like protein 2; Angiopoietin-related protein 2; angiopoietin-related protein-2; Angptl2; ARP2; AW260363; HARP; MGC8889; UNQ170/PRO196

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171100, 23452, 26360

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9R045, Q9UKU9

Gene Symbols:
ANGPTL2

Immunogen:
A synthesized peptide derived from human ANGPTL2(Accession Q9UKU9), corresponding to amino acid residues N247-E297.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG