PIPA5114886

ATF6 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114886-Each-of-1 In Stock ₹ 43,678.38

PIPA5114886 - Each of 1

₹ 43,678.38

In Stock

Quantity

1

Base Price: ₹ 43,678.38

GST (18%): ₹ 7,862.108

Total Price: ₹ 51,540.488

Antigen

ATF6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ATF6

Gene Alias

9130025P16Rik; 9630036G24; AA617266; AA789574; ACHM7; activating transcription factor 6; activating transcription factor 6 alpha; Activating transcription factor 6 beta; ATF 6; Atf6; ATF6 alpha; ATF6A; Atf6alpha; ATF6-alpha; Atf6b; ATF6beta; ATF6-beta; cAMP response element binding protein-related protein; cAMP response element-binding protein-related protein; cAMP responsive element binding protein-like 1; cAMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; Crebl1; Creb-related protein; CREB-RP; Cyclic AMP-dependent transcription factor ATF-6 alpha; cyclic AMP-dependent transcription factor ATF-6 beta; DKFZp686P2194; ESTM49; FLJ21663; G13; Processed cyclic AMP-dependent transcription factor ATF-6 alpha; Processed cyclic AMP-dependent transcription factor ATF-6 beta; Protein G13

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12915, 1388, 226641, 22926, 304962, 406169

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

F6VAN0, G3V909, O35451, P18850, Q99941

Gene Symbols

ATF6, ATF6B

Immunogen

A synthesized peptide derived from human ATF6(Accession P18850), corresponding to amino acid residues T289-K339.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5114936

--

Img

Thermo Scientific

PIPA5116030

--

Img

Thermo Scientific

PIPA5115365

--

Img

Thermo Scientific

PIPA5114882

--

Img

Thermo Scientific

PIPA5114822

--

Img

Thermo Scientific

PIPA5116029

--

Img

Thermo Scientific

PIPA5115927

--

Img

Thermo Scientific

PIPA5115835

--

Description

  • Antibody detects endogenous levels of total ATF6
  • ATF6 is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes
  • It binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3')
  • Binding to ERSE requires binding of NF-Y to ERSE
  • ATF6 could also be involved in activation of transcription by the serum response factor
  • ATF6 exists as a homodimer and heterodimer with ATF6 beta
  • The dimer interacts with the nuclear transcription factor Y (NF-Y) trimer through direct binding to NF-Y subunit C (NF-YC)
  • It Interacts also with the transcription factors GTF2I, YY1 and SRF
  • Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus
  • The basic domain of ATF6 functions as a nuclear localization signal and the basic leucine-zipper domain is sufficient for association with the NF-Y trimer and binding to ERSE
  • During the unfolded protein response an approximately 50 kDa fragment containing the cytoplasmic transcription factor domain is released by proteolysis
  • The cleavage seems to be performed sequentially by site-1 and site-2 proteases
  • ATF6 is N-glycosylated, phosphorylated in vitro by MAPK14/P38MAPK and belongs to the bZIP family.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5114886

--


Antigen:
ATF6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATF6

Gene Alias:
9130025P16Rik; 9630036G24; AA617266; AA789574; ACHM7; activating transcription factor 6; activating transcription factor 6 alpha; Activating transcription factor 6 beta; ATF 6; Atf6; ATF6 alpha; ATF6A; Atf6alpha; ATF6-alpha; Atf6b; ATF6beta; ATF6-beta; cAMP response element binding protein-related protein; cAMP response element-binding protein-related protein; cAMP responsive element binding protein-like 1; cAMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; Crebl1; Creb-related protein; CREB-RP; Cyclic AMP-dependent transcription factor ATF-6 alpha; cyclic AMP-dependent transcription factor ATF-6 beta; DKFZp686P2194; ESTM49; FLJ21663; G13; Processed cyclic AMP-dependent transcription factor ATF-6 alpha; Processed cyclic AMP-dependent transcription factor ATF-6 beta; Protein G13

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12915, 1388, 226641, 22926, 304962, 406169

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
F6VAN0, G3V909, O35451, P18850, Q99941

Gene Symbols:
ATF6, ATF6B

Immunogen:
A synthesized peptide derived from human ATF6(Accession P18850), corresponding to amino acid residues T289-K339.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114887

--


Antigen:
V-ATPase E1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATP6V1E1

Gene Alias:
2410029D23Rik; Atp6e; Atp6e2; ATP6V1E; Atp6v1e1; ATPase H+ transporting V1 subunit E1; ATPase, H+ transporting lysosomal (vacuolar proton pump), 32 kDa; ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E; ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1; ATPase, H+ transporting, lysosomal V1 subunit E1; ATPase, H+ transporting, V1 subunit E; D6Ertd385e; E2; H(+)-ATPase E-like protein; H(+)-transporting two-sector ATPase, 31kDa subunit; H+ ATPase subunit E; H+-transporting ATP synthase chain E, vacuolar; lysosomal 31kDa; P31; vacuolar H(+)-ATPase, E subunit; vacuolar H+ ATPase E1; vacuolar proton pump subunit E 1; V-ATPase 31 kDa subunit; V-ATPase subunit E; V-ATPase subunit E 1; VATPase, H+ transporting, lysosomal V1 subunit E1; V-ATPase, subunit E; Vma4; V-type proton ATPase subunit E 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11973, 297566, 529

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P36543, P50518, Q6PCU2

Gene Symbols:
ATP6V1E1

Immunogen:
A synthesized peptide derived from human ATP6V0E1(Accession O15342), corresponding to amino acid residues M1-V36.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114888

--


Antigen:
ATXN7L1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATXN7L1

Gene Alias:
2810423G08Rik; ataxin 7 like 1; ataxin 7-like 1; ataxin 7-like 4; ataxin-7-like protein 1; Ataxin-7-like protein 4; Atxn7l1; Atxn7l4; KIAA1218; RGD1305730

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
222255, 380753

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9CZ05, Q9ULK2

Gene Symbols:
ATXN7L1

Immunogen:
A synthesized peptide derived from human ATXN7L1(Accession Q9ULK2), corresponding to amino acid residues D96-V146.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114889

--


Antigen:
B7-H6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NCR3LG1

Gene Alias:
B7 homolog 6; B7H6; B7-H6; DKFZp686I21167; DKFZp686O24166; natural cytotoxicity triggering receptor 3 ligand 1; natural killer cell cytotoxicity receptor 3 ligand 1; NCR3LG1; putative Ig-like domain-containing protein DKFZp686O24166/DKFZp686I21167

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
374383

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q68D85

Gene Symbols:
NCR3LG1

Immunogen:
A synthesized peptide derived from human NCR3LG1(Accession Q68D85), corresponding to amino acid residues D375-V425.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG