PIPA5114899
BCL-2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5114899-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5114899 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
BCL-2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Bcl2
Gene Alias
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12043, 24224, 596
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
P10415, P10417, P49950
Gene Symbols
Bcl2
Immunogen
A synthesized peptide derived from human BCL2(Accession P10415), corresponding to amino acid residues A45-L95.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Arthropod, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total Bcl-2
- BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
- The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
- Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
- Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
- Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
- Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
- In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
- Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
- The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.
Compare Similar Items
Show Difference
Antigen: BCL-2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Bcl2
Gene Alias: apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12043, 24224, 596
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P10415, P10417, P49950
Gene Symbols: Bcl2
Immunogen: A synthesized peptide derived from human BCL2(Accession P10415), corresponding to amino acid residues A45-L95.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Arthropod, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
BCL-2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Bcl2
Gene Alias:
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12043, 24224, 596
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P10415, P10417, P49950
Gene Symbols:
Bcl2
Immunogen:
A synthesized peptide derived from human BCL2(Accession P10415), corresponding to amino acid residues A45-L95.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Arthropod, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Bestrophin 2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BEST2
Gene Alias: BEST2; bestrophin 2; bestrophin-2; Hbest2; vitelliform macular dystrophy 2-like 1; vitelliform macular dystrophy 2-like protein 1; VMD2L1; VMD2L-1; VMD2-like gene 1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 212989, 364973, 54831
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q8BGM5, Q8NFU1
Gene Symbols: BEST2
Immunogen: A synthesized peptide derived from human BEST2(Accession Q8NFU1), corresponding to amino acid residues T429-E479.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Bestrophin 2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BEST2
Gene Alias:
BEST2; bestrophin 2; bestrophin-2; Hbest2; vitelliform macular dystrophy 2-like 1; vitelliform macular dystrophy 2-like protein 1; VMD2L1; VMD2L-1; VMD2-like gene 1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
212989, 364973, 54831
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q8BGM5, Q8NFU1
Gene Symbols:
BEST2
Immunogen:
A synthesized peptide derived from human BEST2(Accession Q8NFU1), corresponding to amino acid residues T429-E479.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Bestrophin 3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BEST3
Gene Alias: BEST3; bestrophin 3; bestrophin-3; mBest4; vitelliform macular dystrophy 2-like 3; vitelliform macular dystrophy 2-like protein 3; Vmd2l3
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 144453, 382427
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q6H1V1, Q8N1M1
Gene Symbols: BEST3
Immunogen: A synthesized peptide derived from human BEST3(Accession Q8N1M1), corresponding to amino acid residues S412-L462.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Bestrophin 3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BEST3
Gene Alias:
BEST3; bestrophin 3; bestrophin-3; mBest4; vitelliform macular dystrophy 2-like 3; vitelliform macular dystrophy 2-like protein 3; Vmd2l3
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
144453, 382427
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q6H1V1, Q8N1M1
Gene Symbols:
BEST3
Immunogen:
A synthesized peptide derived from human BEST3(Accession Q8N1M1), corresponding to amino acid residues S412-L462.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: beta-3 Defensin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DEFB103A
Gene Alias: BD3; BD-3; beta defensin 3; beta defensin-3; beta-defensin 103; Beta-defensin 3; DEFB103; DEFB103A; DEFB103B; DEFB3; DEFB-3; defensin beta 103A; defensin, beta 103; defensin, beta 103A; defensin, beta 3; defensin-like protein; HBD3; hBD-3; HBP3; HBP-3
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 414325
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P81534
Gene Symbols: DEFB103A
Immunogen: A synthesized peptide derived from human DEFB103A, DEFB103B(Accession P81534), corresponding to amino acid residues G37-K67.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
beta-3 Defensin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DEFB103A
Gene Alias:
BD3; BD-3; beta defensin 3; beta defensin-3; beta-defensin 103; Beta-defensin 3; DEFB103; DEFB103A; DEFB103B; DEFB3; DEFB-3; defensin beta 103A; defensin, beta 103; defensin, beta 103A; defensin, beta 3; defensin-like protein; HBD3; hBD-3; HBP3; HBP-3
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
414325
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P81534
Gene Symbols:
DEFB103A
Immunogen:
A synthesized peptide derived from human DEFB103A, DEFB103B(Accession P81534), corresponding to amino acid residues G37-K67.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG