PIPA5114978
CD27 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5114978-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5114978 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
CD27
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CD27
Gene Alias
CD antigen 27; CD27; CD27 antigen; CD27 molecule; CD27L receptor; LPFS2; S152; S152. LPFS2; sCD27; soluble CD27; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; TNFSF7; Tp55; Tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
21940, 500318, 939
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (PFA fixed), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
P26842, P41272
Gene Symbols
CD27
Immunogen
A synthesized peptide derived from human CD27(Accession P26842), corresponding to amino acid residues Q55-A105.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total CD27
- CD27 is a 50 kDa member of the tumor necrosis factor (TNF) receptor superfamily that includes CD40 and CD30
- The TNF superfamily members are known for the regulation of cell proliferation and death
- In contrast to the expression of other TNFR/TNF family members, expression of CD27 and its ligand CD70 is predominantly confined to lymphocytes
- High expression levels of CD27 appear to be dependent on proper ligation of antigen receptors
- CD70 expression requires additional co-stimulatory and/or pro-inflammatory signals
- CD27 is expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells
- Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid
- Soluble CD27 is an important prognostic marker of acute and chronic B cell malignancies
- RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70
- CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor
- Diseases associated with CD27 dysfunction include Lymphoproliferative Syndrome 2 and Autosomal Recessive Lymphoproliferative Syndrome.
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Antigen: CD27
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CD27
Gene Alias: CD antigen 27; CD27; CD27 antigen; CD27 molecule; CD27L receptor; LPFS2; S152; S152. LPFS2; sCD27; soluble CD27; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; TNFSF7; Tp55; Tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 21940, 500318, 939
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (PFA fixed), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P26842, P41272
Gene Symbols: CD27
Immunogen: A synthesized peptide derived from human CD27(Accession P26842), corresponding to amino acid residues Q55-A105.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CD27
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CD27
Gene Alias:
CD antigen 27; CD27; CD27 antigen; CD27 molecule; CD27L receptor; LPFS2; S152; S152. LPFS2; sCD27; soluble CD27; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; TNFSF7; Tp55; Tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
21940, 500318, 939
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (PFA fixed), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P26842, P41272
Gene Symbols:
CD27
Immunogen:
A synthesized peptide derived from human CD27(Accession P26842), corresponding to amino acid residues Q55-A105.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CDK12
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDK12
Gene Alias: 1810022J16Rik; AI646528; CDC2-related kinase 7; CDC2-related kinase, arginine/serine-rich; CDC2-related protein kinase 7; Cdk12; Cell division cycle 2-related protein kinase 7; cell division protein kinase 12; CRK7; CRKR; Crkrs; cyclin dependent kinase 12; cyclin-dependent kinase 12; cyclin-dependent kinase 12 isoform; D11Ertd752e; H KIAA0904; hCDK12; Kiaa0904; Pksc; Protein kinase for splicing component
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 192350, 51755
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q3MJK5, Q9NYV4
Gene Symbols: CDK12
Immunogen: A synthesized peptide derived from human CDK12(Accession Q9NYV4), corresponding to amino acid residues L1213-E1263.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CDK12
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDK12
Gene Alias:
1810022J16Rik; AI646528; CDC2-related kinase 7; CDC2-related kinase, arginine/serine-rich; CDC2-related protein kinase 7; Cdk12; Cell division cycle 2-related protein kinase 7; cell division protein kinase 12; CRK7; CRKR; Crkrs; cyclin dependent kinase 12; cyclin-dependent kinase 12; cyclin-dependent kinase 12 isoform; D11Ertd752e; H KIAA0904; hCDK12; Kiaa0904; Pksc; Protein kinase for splicing component
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
192350, 51755
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q3MJK5, Q9NYV4
Gene Symbols:
CDK12
Immunogen:
A synthesized peptide derived from human CDK12(Accession Q9NYV4), corresponding to amino acid residues L1213-E1263.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CD32
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FCGR2A
Gene Alias: CD32; CD32 receptor 2; CD32 receptor 2a; CD32A; CD32B; CD32C; CDW32; Fc fragment of IgG receptor IIa; Fc fragment of IgG receptor IIb; Fc fragment of IgG receptor IIc (gene/pseudogene); Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc fragment of IgG, low affinity IIa, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc fragment of IgG, low affinity IIc, receptor for (CD32); Fc gamma receptor II; Fc gamma receptor IIa; Fc gamma receptor IIb; Fc gamma receptor IIC; Fc gamma RIIb; FCG2; Fc-gamma receptor II; fc-gamma RII; Fc-gamma RII-a; fc-gamma RII-b; Fc-gamma RII-c; fc-gamma-RIIa; Fc-gamma-RIIb; fc-gamma-RIIc; Fc-gamma-RII-D; FcGR; FCGR2; FCGR2A; FCGR2A1; FCGR2B; FCGR2C; fcRII; fcRII-a; fcRII-b; FCRIIC; FGFR2B; IGFR2; IgG Fc fragment receptor; IgG Fc gamma receptor II; igG Fc receptor II; IgG Fc receptor II-a; igG Fc receptor II-b; Ig
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2212, 2213, 9103
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P12318, P31994, P31995
Gene Symbols: FCGR2A, FCGR2B, FCGR2C
Immunogen: A synthesized peptide derived from human FCGR2A(Accession P12318), corresponding to amino acid residues Q258-P308.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CD32
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FCGR2A
Gene Alias:
CD32; CD32 receptor 2; CD32 receptor 2a; CD32A; CD32B; CD32C; CDW32; Fc fragment of IgG receptor IIa; Fc fragment of IgG receptor IIb; Fc fragment of IgG receptor IIc (gene/pseudogene); Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc fragment of IgG, low affinity IIa, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc fragment of IgG, low affinity IIc, receptor for (CD32); Fc gamma receptor II; Fc gamma receptor IIa; Fc gamma receptor IIb; Fc gamma receptor IIC; Fc gamma RIIb; FCG2; Fc-gamma receptor II; fc-gamma RII; Fc-gamma RII-a; fc-gamma RII-b; Fc-gamma RII-c; fc-gamma-RIIa; Fc-gamma-RIIb; fc-gamma-RIIc; Fc-gamma-RII-D; FcGR; FCGR2; FCGR2A; FCGR2A1; FCGR2B; FCGR2C; fcRII; fcRII-a; fcRII-b; FCRIIC; FGFR2B; IGFR2; IgG Fc fragment receptor; IgG Fc gamma receptor II; igG Fc receptor II; IgG Fc receptor II-a; igG Fc receptor II-b; Ig
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2212, 2213, 9103
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P12318, P31994, P31995
Gene Symbols:
FCGR2A, FCGR2B, FCGR2C
Immunogen:
A synthesized peptide derived from human FCGR2A(Accession P12318), corresponding to amino acid residues Q258-P308.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PAF49
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Cd3eap
Gene Alias: 1190028F09; 2610103M17Rik; A34.5; antis; Anti-sense to ERCC-1 protein; antisense to ERCC-1 protein; Ase1; ASE-1; CAST; CD3 epsilon associated protein; antisense to Ercc1; CD3E antigen, epsilon polypeptide associated protein; CD3E antigen, epsilon polypeptide-associated protein; CD3e molecule associated protein; CD3e molecule, epsilon associated protein; Cd3eap; CD3E-associated protein; CD3-epsilon-associated protein; DNA-directed RNA polymerase I subunit RPA34; PAF49; RGD1305916; RNA polymerase I-associated factor PAF49
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10849
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: O15446
Gene Symbols: Cd3eap
Immunogen: A synthesized peptide derived from human CD3EAP(Accession O15446), corresponding to amino acid residues L441-G491.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PAF49
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Cd3eap
Gene Alias:
1190028F09; 2610103M17Rik; A34.5; antis; Anti-sense to ERCC-1 protein; antisense to ERCC-1 protein; Ase1; ASE-1; CAST; CD3 epsilon associated protein; antisense to Ercc1; CD3E antigen, epsilon polypeptide associated protein; CD3E antigen, epsilon polypeptide-associated protein; CD3e molecule associated protein; CD3e molecule, epsilon associated protein; Cd3eap; CD3E-associated protein; CD3-epsilon-associated protein; DNA-directed RNA polymerase I subunit RPA34; PAF49; RGD1305916; RNA polymerase I-associated factor PAF49
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10849
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O15446
Gene Symbols:
Cd3eap
Immunogen:
A synthesized peptide derived from human CD3EAP(Accession O15446), corresponding to amino acid residues L441-G491.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG