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PIPA5115084

CYP2D6 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Each of 1 PIPA5115084-Each-of-1 In Stock ₹ 44,705.10

PIPA5115084 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CYP2D6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CYP2D6

Gene Alias

AI303445; Cholesterol 25-hydroxylase; CPD6; CYP2D; Cyp2d10; Cyp2d-10; Cyp2d13; Cyp2d18; Cyp2d-18; Cyp2d22; Cyp2d3; Cyp2d-3; Cyp2d4; Cyp2d-4; Cyp2d4v1; Cyp2d4v2; Cyp2d6; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; CYP2DL1; CYPIID10; CYPIID18; CYPIID3; CYPIID4; CYPIID6; Cytochrome P450 2D10; cytochrome P450 2d18; Cytochrome P450 2D-29; Cytochrome P450 2D3; cytochrome P450 2D-35; cytochrome P450 2D4; Cytochrome P450 2D6; cytochrome P450 family 2 subfamily D member 6; cytochrome P450, 2d10; cytochrome P450, family 2, subfamily d, polypeptide 10; cytochrome P450, family 2, subfamily d, polypeptide 13; cytochrome P450, family 2, subfamily d, polypeptide 22; cytochrome P450, family 2, subfamily d, polypeptide 3; cytochrome P450, family 2, subfamily d, polypeptide 4; cytochrome P450, family 2, subfamily d, polypeptide 6; cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2; cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2; cytochrome P450, subfamily 2D, polypeptide 6; cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2; cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2; cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6; cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1; cytochrome P450, subfamily IID, polypeptide 6; Cytochrome P450, subfamily IID3; Cytochrome P450, subfamily IID4; cytochrome P450-16-alpha; Cytochrome P450CB; Cytochrome P450-CMF3; cytochrome P450-DB1; Cytochrome P450-DB3; cytochrome P450-DB4; debrisoquine 4-hydroxylase; flavoprotein-linked monooxygenase; microsomal monooxygenase; nonfunctional cytochrome P450 2D6; P450 2D-29/2D-35; P450-2D; P450C2D; P450-CMF3; P450DB1; P450-DB1; P450-DB3; P450-DB4; testosterone 16-alpha hydroxylase; xenobiotic monooxygenase

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1565, 171522, 24303

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

P10635, P12938, Q64680

Gene Symbols

Cyp2d3, Cyp2d4, CYP2D6

Immunogen

A synthesized peptide derived from human CYP2D6(Accession P10635), corresponding to amino acid residues E257-M307.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total Cytochrome P450 2D6
  • Cytochrome p450 2D6 (CYP2D6) is a member of the cytochrome P450 superfamily of enzymes
  • The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids
  • This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs
  • Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine and propafenone, both anti-arrythmic drugs; and amitryptiline, an anti-depressant
  • The gene is highly polymorphic in the population; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates
  • The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1
  • Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Compare Similar Items

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Thermo Scientific

PIPA5115084

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Antigen:
CYP2D6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CYP2D6
Gene Alias:
AI303445; Cholesterol 25-hydroxylase; CPD6; CYP2D; Cyp2d10; Cyp2d-10; Cyp2d13; Cyp2d18; Cyp2d-18; Cyp2d22; Cyp2d3; Cyp2d-3; Cyp2d4; Cyp2d-4; Cyp2d4v1; Cyp2d4v2; Cyp2d6; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; CYP2DL1; CYPIID10; CYPIID18; CYPIID3; CYPIID4; CYPIID6; Cytochrome P450 2D10; cytochrome P450 2d18; Cytochrome P450 2D-29; Cytochrome P450 2D3; cytochrome P450 2D-35; cytochrome P450 2D4; Cytochrome P450 2D6; cytochrome P450 family 2 subfamily D member 6; cytochrome P450, 2d10; cytochrome P450, family 2, subfamily d, polypeptide 10; cytochrome P450, family 2, subfamily d, polypeptide 13; cytochrome P450, family 2, subfamily d, polypeptide 22; cytochrome P450, family 2, subfamily d, polypeptide 3; cytochrome P450, family 2, subfamily d, polypeptide 4; cytochrome P450, family 2, subfamily d, polypeptide 6; cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2; cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2; cytochrome P450, subfamily 2D, polypeptide 6; cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2; cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2; cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6; cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1; cytochrome P450, subfamily IID, polypeptide 6; Cytochrome P450, subfamily IID3; Cytochrome P450, subfamily IID4; cytochrome P450-16-alpha; Cytochrome P450CB; Cytochrome P450-CMF3; cytochrome P450-DB1; Cytochrome P450-DB3; cytochrome P450-DB4; debrisoquine 4-hydroxylase; flavoprotein-linked monooxygenase; microsomal monooxygenase; nonfunctional cytochrome P450 2D6; P450 2D-29/2D-35; P450-2D; P450C2D; P450-CMF3; P450DB1; P450-DB1; P450-DB3; P450-DB4; testosterone 16-alpha hydroxylase; xenobiotic monooxygenase
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1565, 171522, 24303
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P10635, P12938, Q64680
Gene Symbols:
Cyp2d3, Cyp2d4, CYP2D6
Immunogen:
A synthesized peptide derived from human CYP2D6(Accession P10635), corresponding to amino acid residues E257-M307.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG

Img

Thermo Scientific

PIPA5115085

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Antigen:
CYP2U1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CYP2U1
Gene Alias:
8430436A10Rik; Cyp2u1; Cytochrome P450 2U1; cytochrome P450 family 2 subfamily U member 1; cytochrome P450, 2u1; cytochrome P450, family 2, subfamily U, polypeptide 1; P450TEC; spastic paraplegia 49; SPG49; SPG56
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
113612, 310848, 71519
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q4V8D1, Q7Z449, Q9CX98
Gene Symbols:
CYP2U1
Immunogen:
A synthesized peptide derived from human CYP2U1(Accession Q7Z449), corresponding to amino acid residues E286-S336.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG

Img

Thermo Scientific

PIPA5115086

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Antigen:
CYP46A1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CYP46A1
Gene Alias:
CH24H; Cholesterol 24-hydroxylase; Cholesterol 24-monooxygenase; Cholesterol 24S-hydroxylase; cholestrol 24-hydroxylase; CP46; CYP46; CYP46A1; Cytochrome P450 46A1; cytochrome P450 family 46 subfamily A member 1; cytochrome P450, 46 (cholesterol 24-hydroxylase); cytochrome P450, 46a1 (cholesterol 24-hydroxylase); cytochrome P450, family 46, subfamily A, polypeptide 1; cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10858, 13116
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q9WVK8, Q9Y6A2
Gene Symbols:
CYP46A1
Immunogen:
A synthesized peptide derived from human CYP46A1(Accession Q9Y6A2), corresponding to amino acid residues Q213-E263.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate
Product Type:
Antibody
Isotype:
IgG

Img

Thermo Scientific

PIPA5115088

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Antigen:
Cytokeratin 6A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
KRT6A
Gene Alias:
2310016L08Rik; 60-kDa keratin; CK6A; CK-6A; CK6C; CK-6C; CK6D; CK-6D; CK-6E; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; cytokeratin-6A; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; Hom s 5; K6A; K6a keratin; K6C; K6D; kamp-keratin derived antimicrobial peptide; KDAMP; Ker2; keratin 6A; keratin 6A, , type II; keratin 6A, type II; keratin complex 2, basic, gene 6a; keratin complex 2, basic, gene 6c; keratin complex 2, gene 6a; keratin K6; keratin K6h; keratin, epidermal type II, K6A; keratin, type II cytoskeletal 6A; keratin, type II cytoskeletal 6C; Keratin-6A; keratin-6-alpha; keratin-6C; Krt2-6; Krt2-6a; Krt2-6c; Krt6; KRT6A; KRT6C; KRT6D; LOC683313; mK6[a]; MK6a; mK6-alpha; PC3; similar to keratin complex 2, basic, gene 6a; type-II keratin Kb12; type-II keratin Kb6
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
120093743, 16687, 3853
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P02538, P50446, Q4FZU2
Gene Symbols:
KRT6A
Immunogen:
A synthesized peptide derived from human KRT6A(Accession P02538), corresponding to amino acid residues A2-G52.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG