PIPA5115121

DIABLO Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5115121-Each-of-1 In Stock ₹ 44,705.10

PIPA5115121 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

DIABLO

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DIABLO

Gene Alias

0610041G12Rik; 1700006L01Rik; AU040403; DFNA64; DIABLO; diablo homolog (Drosophila); diablo homolog, mitochondrial; diablo IAP-binding mitochondrial protein; diablo, IAP-binding mitochondrial protein; diablo-like protein; DIABLO-S; direct IAP binding protein with low PI; direct IAP-binding protein with low pI; FLJ10537; FLJ25049; hCG_1782202; Second mitochondria-derived activator of caspase; Smac; Smac protein; SMAC3

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

288753, 56616, 66593

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q9JIQ3, Q9NR28

Gene Symbols

DIABLO

Immunogen

A synthesized peptide derived from human DIABLO(Accession Q9NR28), corresponding to amino acid residues E215-D239.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total DIABLO
  • DIABLO (smac), a mitochondrial protein, activates various forms of apoptosis
  • This activation may be due to the neutralization of one or more members of the IAP family of apoptosis inhibitory proteins
  • Smac exits the mitochondria and enter the cytosol during certain apoptosis triggered events
  • Mitochondrial-mediated apoptosis is important in animal development and tissue homeostasis, with alterations resulting in a range of malignant disorders
  • Upon apoptotic stimuli, the mitochondrial proteins cytochrome c and Smac/DIABLO are released into the cytosol
  • The release of these proteins, however, occurs via different mechanisms
  • Smac/DIABLO has also been found to play a key role in regulating the sensitization of cancer cells to apoptosis (both immune and drug-induced).

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5115121

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Antigen:
DIABLO

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DIABLO

Gene Alias:
0610041G12Rik; 1700006L01Rik; AU040403; DFNA64; DIABLO; diablo homolog (Drosophila); diablo homolog, mitochondrial; diablo IAP-binding mitochondrial protein; diablo, IAP-binding mitochondrial protein; diablo-like protein; DIABLO-S; direct IAP binding protein with low PI; direct IAP-binding protein with low pI; FLJ10537; FLJ25049; hCG_1782202; Second mitochondria-derived activator of caspase; Smac; Smac protein; SMAC3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
288753, 56616, 66593

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9JIQ3, Q9NR28

Gene Symbols:
DIABLO

Immunogen:
A synthesized peptide derived from human DIABLO(Accession Q9NR28), corresponding to amino acid residues E215-D239.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115122

--


Antigen:
DIAPH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DIAPH1

Gene Alias:
D18Wsu154e; DFNA1; DIA1; Diap1; Diaph1; diaphanous 1; diaphanous homolog 1; diaphanous homolog 1 (Drosophila); diaphanous related formin 1; diaphanous-1; diaphanous-related formin 1; Diaphanous-related formin-1; DRF1; FLJ25265; hDIA1; LFHL1; mDIA1; p140DIA; p140mDia; Protein diaphanous homolog 1; SCBMS

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13367, 1729, 307483

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O08808, O60610

Gene Symbols:
DIAPH1

Immunogen:
A synthesized peptide derived from human DIAPH1(Accession O60610), corresponding to amino acid residues K42-V92.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115124

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Antigen:
Dicer

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DICER1

Gene Alias:
1110006F08Rik; D12Ertd7e; DCR; DCR1; DCR-1; Dicer; dicer 1 ribonuclease III; dicer 1, double-stranded RNA-specific endoribonuclease; dicer 1, ribonuclease III; dicer 1, ribonuclease type III; Dicer1; Dicer1, Dcr-1 homolog; Dicer1e; double-strand-specific ribonuclease mDCR-1; endoribonuclease Dicer; Helicase MOI; helicase with RNAse motif; helicase-moi; HERNA; K12H4.8-LIKE; KIAA0928; mKIAA0928; MNG1; RMSE2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
192119, 23405, 299284

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8R418, Q9UPY3

Gene Symbols:
DICER1

Immunogen:
A synthesized peptide derived from human DICER1(Accession Q9UPY3), corresponding to amino acid residues K1516-L1566.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115125

--


Antigen:
DKK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DKK2

Gene Alias:
dickkopf 2; dickkopf 2 homolog; Dickkopf gene 2; dickkopf homolog 1; dickkopf homolog 2; dickkopf homolog 2 (Xenopus laevis); dickkopf homolog 4; dickkopf related protein-2; dickkopf WNT signaling pathway inhibitor 2; dickkopf-2; Dickkopf-related protein 2; DKK2; DKK-2; Dkk4; hDkk-2; mDkk-2; UNQ682/PRO1316

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27123, 295445, 56811

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9QYZ8, Q9UBU2

Gene Symbols:
DKK2

Immunogen:
A synthesized peptide derived from human DKK2(Accession Q9UBU2), corresponding to amino acid residues P129-E179.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG