PIPA5115128

DNA Ligase IV Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5115128-Each-of-1 In Stock ₹ 44,705.10

PIPA5115128 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

DNA Ligase IV

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LIG4

Gene Alias

5830471N16Rik; DNA joinase; DNA ligase (ATP) 4; DNA ligase 4; DNA ligase IV; DNA repair enzyme; Lig4; LIG4S; ligase IV, DNA, ATP-dependent; polydeoxyribonucleotide synthase [ATP] 4; polynucleotide ligase; sealase; tiny

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3981

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

P49917

Gene Symbols

LIG4

Immunogen

A synthesized peptide derived from human LIG4(Accession P49917), corresponding to amino acid residues K626-P676.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total DNA Ligase IV
  • The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction
  • This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ)
  • This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK)
  • Both XRCC4 and DNA-PK are known to be required for NHEJ
  • The crystal structure of the complex formed by this protein and XRCC4 has been resolved
  • Defects in this gene are the cause of LIG4 syndrome
  • Alternatively spliced transcript variants encoding the same protein have been observed.

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Thermo Scientific

PIPA5115128

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Antigen:
DNA Ligase IV

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LIG4

Gene Alias:
5830471N16Rik; DNA joinase; DNA ligase (ATP) 4; DNA ligase 4; DNA ligase IV; DNA repair enzyme; Lig4; LIG4S; ligase IV, DNA, ATP-dependent; polydeoxyribonucleotide synthase [ATP] 4; polynucleotide ligase; sealase; tiny

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3981

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P49917

Gene Symbols:
LIG4

Immunogen:
A synthesized peptide derived from human LIG4(Accession P49917), corresponding to amino acid residues K626-P676.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115131

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Antigen:
DNA2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNA2

Gene Alias:
DNA replication ATP-dependent helicase DNA2; DNA replication ATP-dependent helicase/nuclease DNA2; DNA replication ATP-dependent helicase-like homolog; DNA replication helicase 2 homolog; DNA replication helicase 2 homolog (yeast); DNA replication helicase 2-like; DNA replication helicase/nuclease 2; DNA replication nuclease DNA2; DNA2; DNA2L; DNA2-like helicase; E130315B21Rik; hDNA2; Kiaa0083; LOW QUALITY PROTEIN: DNA replication ATP-dependent helicase/nuclease DNA2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1763, 327762

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P51530, Q6ZQJ5

Gene Symbols:
DNA2

Immunogen:
A synthesized peptide derived from human DNA2(Accession P51530), corresponding to amino acid residues T430-G480.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5115132

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Antigen:
DNAH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNAH1

Gene Alias:
axonemal beta dynein heavy chain 1; Ciliary dynein heavy chain 1; DHC7; Dlp1; DNAH1; DNAH1 variant protein; Dnahc1; dynein axonemal heavy chain 1; dynein heavy chain 1, axonemal; dynein, axonemal, heavy chain 1; dynein, axonemal, heavy polypeptide 1; hDHC7; Heat shock regulated protein 1; HL11; HL-11; HSRF-1; KIAA1410; RGD1311110; testicular tissue protein Li 60; XLHSRF-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171339, 25981

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q63164, Q9P2D7

Gene Symbols:
DNAH1

Immunogen:
A synthesized peptide derived from human DNAH1(Accession Q9P2D7), corresponding to amino acid residues T3124-Q3174.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5115133

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Antigen:
DNAH5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNAH5

Gene Alias:
AU022615; Axonemal beta dynein heavy chain 5; axonemal dynein heavy chain 5; b2b1134Clo; b2b1154Clo; b2b1537Clo; b2b1565Clo; b2b601Clo; CILD3; Ciliary dynein heavy chain 5; DLP5; Dnah5; Dnahc5; Dnahc8; dynein axonemal heavy chain 5; dynein heavy chain 5, axonemal; dynein, axon, heavy chain 5; dynein, axonemal, heavy chain 5; dynein, axonemal, heavy polypeptide 5; dynein-like protein 5; HL1; KIAA1603; KTGNR; Mdnah5; mKIAA1603; PCD

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
110082, 1767, 294854

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8TE73, Q8VHE6

Gene Symbols:
DNAH5

Immunogen:
A synthesized peptide derived from human DNAH5(Accession Q8TE73), corresponding to amino acid residues T2527-Q2577.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG