PIPA5115330

GSDMD Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5115330-Each-of-1 In Stock ₹ 44,705.10

PIPA5115330 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

GSDMD

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GSDMD

Gene Alias

1810036L03Rik; AW558049; DF5L; Dfna5l; FKSG10; gasdermin D; gasdermin domain containing 1; gasdermin domain-containing protein 1; Gasdermin-D; Gasdermin-D, C-terminal; Gasdermin-D, N-terminal; GSDMD; GSDMDC1; GSDMD-CT; GSDMD-NT; M2-4

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

315084, 69146, 79792

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

P57764, Q9D8T2

Gene Symbols

GSDMD

Immunogen

A synthesized peptide derived from human GSDMD(Accession P57764), corresponding to amino acid residues W50-G100.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total GSDMD protein, including precursor and the cleaved N-terminal fragment
  • GSDMD (gasdermin-D) promotes pyroptosis in response to microbial infection and danger signals
  • It is produced by the cleavage of gasdermin-D by inflammatory caspases CASP1 or CASP4 in response to canonical, as well as, non-canonical (such as cytosolic LPS) inflammasome activators
  • After cleavage, GSDMD moves to the plasma membrane where it strongly binds to inner leaflet lipids including phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-biphosphate, phosphatidylinositol (3,4,5)-biphosphate, phosphatidic acid, and phosphatidylserine
  • GSDMD also exhibits bactericidal activity.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5115330

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Antigen:
GSDMD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GSDMD

Gene Alias:
1810036L03Rik; AW558049; DF5L; Dfna5l; FKSG10; gasdermin D; gasdermin domain containing 1; gasdermin domain-containing protein 1; Gasdermin-D; Gasdermin-D, C-terminal; Gasdermin-D, N-terminal; GSDMD; GSDMDC1; GSDMD-CT; GSDMD-NT; M2-4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
315084, 69146, 79792

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P57764, Q9D8T2

Gene Symbols:
GSDMD

Immunogen:
A synthesized peptide derived from human GSDMD(Accession P57764), corresponding to amino acid residues W50-G100.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5115331

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Antigen:
GSK3 alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gsk3a

Gene Alias:
2700086H06Rik; DKFZp686D0638; FA; factor A; glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 alpha b; glycogen synthase kinase 3 alpha b; glycogen synthase kinase-3 alpha; glycogen synthase kinase-3 alpha; GSK3; GSK-3 alpha; GSK-3[a]; GSK-3[b]; gsk3a; gsk3ab; gsk-3-alpha; OTTHUMP00000198368; Serine/threonine-protein kinase GSK3A

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2931, 50686, 606496

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P18265, P49840, Q2NL51

Gene Symbols:
Gsk3a

Immunogen:
A synthesized peptide derived from human GSK3A(Accession P49840), corresponding to amino acid residues M1-T46.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5115332

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Antigen:
GSR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gsr

Gene Alias:
AI325518; D8Ertd238e; epididymis luminal protein 75; epididymis secretory sperm binding protein Li 122m; GLUR; glutathione reductase; glutathione reductase 1; glutathione reductase, mitochondrial; glutathione S-reductase; glutathione-disulfide reductase; GR; Gr1; Gr-1; GRase; GRD1; GSR; HEL-75; HEL-S-122m; hypothetical protein LOC553575; zgc:110010

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116686, 2936

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P00390, P70619

Gene Symbols:
Gsr

Immunogen:
A synthesized peptide derived from human GSR(Accession P00390), corresponding to amino acid residues K392-T442.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5115333

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Antigen:
GSTT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gstt1

Gene Alias:
AI255817; Glutathione S-transferase 1 (theta); glutathione S-transferase 5; glutathione S-transferase theta 1; glutathione S-transferase theta-1; glutathione S-transferase, theta 1; glutathione transferase T1-1; GST 5-5; GST class-theta-1; GSTT1; Gstt1-1; GSTYRS; similar to Glutathione S-transferase theta 1 (GST class-theta 1) (Glutathione transferase T1-1)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14871, 25260, 2952

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P30711, Q01579, Q64471

Gene Symbols:
Gstt1

Immunogen:
A synthesized peptide derived from human GSTT1(Accession P30711), corresponding to amino acid residues M1-N49.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG