PIPA5115546
MARCH8 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5115546-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5115546 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
MARCH8
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MARCH8
Gene Alias
1300017E09Rik; cellular modulator of immune recognition; cellular modulator of immune recognition (c-MIR); CMIR; c-MIR; c-mir, cellular modulator of immune recognition; E3 ubiquitin-protein ligase MARCH8; E3 ubiquitin-protein ligase MARCHF8; E3 ubiquitin-protein ligase MARCH8; March8; MARCHF8; MARCH-VIII; membrane associated ring finger 8; membrane associated ring-CH-type finger 8; membrane-associated ring finger (C3HC4) 8; membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase; membrane-associated RING finger protein 8; Membrane-associated RING-CH protein VIII; MIR; RING finger protein 178; RING-type E3 ubiquitin transferase MARCH8; RING-type E3 ubiquitin transferase MARCHF8; RNF178; RP11-67C2.1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
220972
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
Q5T0T0
Gene Symbols
MARCH8
Immunogen
A synthesized peptide derived from human MARCH8(Accession Q5T0T0), corresponding to amino acid residues E251-V291.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total MARCH8
- MARCH8 (c-MIR) is a novel E3 ubiquitin ligase designated as the modulator of immune recognition (MIR) family, whose catalytic domain is a variant RING domain (RING-CH domain)
- MARCH8 was found as a functional and structural homolog of KSHV MIR1 and MIR2
- MARCH8 targets B7-2 to lysosomal degradation and down-regulates the B7-2 surface expression through ubiquitination of its cytoplasmic tail
- Furthermore, MARCH8 has been shown to down-regulate the expression of transferrin receptor and Fas, an important molecule for the induction of apoptosis
- MARCH8 is the first example of an E3 ubiquitin ligase that is capable of inhibiting MHC II expression
- Recent findings suggest that MARCH8 may regulate immune responses by promoting ubiquitination of MHC-II and CD86, leading to their subsequent endocytosis and lysosomal degradation.
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Antigen: MARCH8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MARCH8
Gene Alias: 1300017E09Rik; cellular modulator of immune recognition; cellular modulator of immune recognition (c-MIR); CMIR; c-MIR; c-mir, cellular modulator of immune recognition; E3 ubiquitin-protein ligase MARCH8; E3 ubiquitin-protein ligase MARCHF8; E3 ubiquitin-protein ligase MARCH8; March8; MARCHF8; MARCH-VIII; membrane associated ring finger 8; membrane associated ring-CH-type finger 8; membrane-associated ring finger (C3HC4) 8; membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase; membrane-associated RING finger protein 8; Membrane-associated RING-CH protein VIII; MIR; RING finger protein 178; RING-type E3 ubiquitin transferase MARCH8; RING-type E3 ubiquitin transferase MARCHF8; RNF178; RP11-67C2.1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 220972
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q5T0T0
Gene Symbols: MARCH8
Immunogen: A synthesized peptide derived from human MARCH8(Accession Q5T0T0), corresponding to amino acid residues E251-V291.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MARCH8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MARCH8
Gene Alias:
1300017E09Rik; cellular modulator of immune recognition; cellular modulator of immune recognition (c-MIR); CMIR; c-MIR; c-mir, cellular modulator of immune recognition; E3 ubiquitin-protein ligase MARCH8; E3 ubiquitin-protein ligase MARCHF8; E3 ubiquitin-protein ligase MARCH8; March8; MARCHF8; MARCH-VIII; membrane associated ring finger 8; membrane associated ring-CH-type finger 8; membrane-associated ring finger (C3HC4) 8; membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase; membrane-associated RING finger protein 8; Membrane-associated RING-CH protein VIII; MIR; RING finger protein 178; RING-type E3 ubiquitin transferase MARCH8; RING-type E3 ubiquitin transferase MARCHF8; RNF178; RP11-67C2.1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
220972
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q5T0T0
Gene Symbols:
MARCH8
Immunogen:
A synthesized peptide derived from human MARCH8(Accession Q5T0T0), corresponding to amino acid residues E251-V291.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MARS
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MARS1
Gene Alias: CMT2U; cytosolic methionyl-tRNA synthetase; id:ibd5106; ILFS2; ILLD; MARS; mars protein; mars1; methionine tRNA ligase; methionine--tRNA ligase, cytoplasmic; methionine-tRNA synthetase; methionyl trna synthetase; methionyl-tRNA synthetase; methionyl-tRNA synthetase 1; methionyl-tRNA synthetase, cytoplasmic; metRS; MRS; Mtrns; SPG70; Unknown (protein for MGC:134096); zgc:66122
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 216443, 299851, 4141
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P56192, Q68FL6
Gene Symbols: MARS1
Immunogen: A synthesized peptide derived from human MARS(Accession P56192), corresponding to amino acid residues G570-Y620.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MARS
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MARS1
Gene Alias:
CMT2U; cytosolic methionyl-tRNA synthetase; id:ibd5106; ILFS2; ILLD; MARS; mars protein; mars1; methionine tRNA ligase; methionine--tRNA ligase, cytoplasmic; methionine-tRNA synthetase; methionyl trna synthetase; methionyl-tRNA synthetase; methionyl-tRNA synthetase 1; methionyl-tRNA synthetase, cytoplasmic; metRS; MRS; Mtrns; SPG70; Unknown (protein for MGC:134096); zgc:66122
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
216443, 299851, 4141
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P56192, Q68FL6
Gene Symbols:
MARS1
Immunogen:
A synthesized peptide derived from human MARS(Accession P56192), corresponding to amino acid residues G570-Y620.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MAST1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAST1
Gene Alias: 9430008B02Rik; KIAA0973; MAST1; mast1 {ECO:0000312; microtubule associated serine/threonine kinase 1; microtubule-associated serine/threonine-protein kinase 1; RGD:631372}; SAST; SAST170; syntrophin associated serine/threonine kinase; syntrophin-associated serine/threonine-protein kinase; syntrophin-associated serine-threonine protein kinase
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22983, 353118, 56527
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q810W7, Q9R1L5, Q9Y2H9
Gene Symbols: MAST1
Immunogen: A synthesized peptide derived from human MAST1(Accession Q9Y2H9), corresponding to amino acid residues H340-L390.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MAST1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAST1
Gene Alias:
9430008B02Rik; KIAA0973; MAST1; mast1 {ECO:0000312; microtubule associated serine/threonine kinase 1; microtubule-associated serine/threonine-protein kinase 1; RGD:631372}; SAST; SAST170; syntrophin associated serine/threonine kinase; syntrophin-associated serine/threonine-protein kinase; syntrophin-associated serine-threonine protein kinase
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22983, 353118, 56527
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q810W7, Q9R1L5, Q9Y2H9
Gene Symbols:
MAST1
Immunogen:
A synthesized peptide derived from human MAST1(Accession Q9Y2H9), corresponding to amino acid residues H340-L390.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MAT2A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAT2A
Gene Alias: adoMet synthase 2; adoMet synthetase 2; AMS2; D630045P18Rik; MAT 2; MAT2A; MATA2; MATII; MAT-II; Methionine adenosyltransferase 2; methionine adenosyltransferase 2A; Methionine adenosyltransferase II; methionine adenosyltransferase II, alpha; non-hepatic-type S-adenosylmethionine synthetase; S-adenosylmethionine synthase; S-adenosylmethionine synthase isoform type-2; S-adenosylmethionine synthetase isoform type-2; Sams2; testicular tissue protein Li 121
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 171347, 232087, 4144
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P18298, P31153, Q3THS6
Gene Symbols: MAT2A
Immunogen: A synthesized peptide derived from human MAT2A(Accession P31153), corresponding to amino acid residues P357-Y395.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MAT2A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAT2A
Gene Alias:
adoMet synthase 2; adoMet synthetase 2; AMS2; D630045P18Rik; MAT 2; MAT2A; MATA2; MATII; MAT-II; Methionine adenosyltransferase 2; methionine adenosyltransferase 2A; Methionine adenosyltransferase II; methionine adenosyltransferase II, alpha; non-hepatic-type S-adenosylmethionine synthetase; S-adenosylmethionine synthase; S-adenosylmethionine synthase isoform type-2; S-adenosylmethionine synthetase isoform type-2; Sams2; testicular tissue protein Li 121
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
171347, 232087, 4144
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P18298, P31153, Q3THS6
Gene Symbols:
MAT2A
Immunogen:
A synthesized peptide derived from human MAT2A(Accession P31153), corresponding to amino acid residues P357-Y395.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG