PIPA5115621
SCN10A Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5115621-Each-of-1 | In Stock | ₹ 43,678.38 |
PIPA5115621 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,678.38
GST (18%): ₹ 7,862.108
Total Price: ₹ 51,540.488
Antigen
SCN10A
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Scn10a
Gene Alias
FEPS2; hPN3; mPN3; Na(V)1.8; Nav1.8; peripheral nerve sodium channel 3; PN3; Scn10a; Sensory neuron sodium channel; SNS; Sodium channel protein type 10 subunit alpha; sodium channel protein type X subunit alpha; sodium channel type X alpha polypeptide; sodium channel voltage-gated type X alpha polypeptide; sodium channel, voltage gated, type X alpha subunit; sodium channel, voltage-gated, type 10, alpha polypeptide; sodium channel, voltage-gated, type X, alpha; sodium channel, voltage-gated, type X, alpha polypeptide; sodium channel, voltage-gated, type X, alpha subunit; sodium voltage-gated channel alpha subunit 10; voltage gated sodium channel; voltage-gated sodium channel subunit alpha Nav1.8
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20264, 29571, 6336
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
Q62968, Q6QIY3, Q9Y5Y9
Gene Symbols
Scn10a
Immunogen
A synthesized peptide derived from human SCN10A(Accession Q9Y5Y9), corresponding to amino acid residues R461-P481.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total Nav1.8
- Scn10a is a tetrodotoxin-resistant voltage-gated sodium channel alpha subunit
- Epithelial sodium channels are amiloride-sensitive members of the Degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels
- Scn10a mediates the voltage-dependent sodium ion permeability of excitable membranes
- Assuming opened or closed conformations in response to the voltage difference across the membrane, Scn10a forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient
- Scn10a also plays a role in neuropathic pain mechanisms
- Structurally, members of Deg/ENaC superfamily of ion channels share organizational similarity in that they all possess two short intracellular amino and carboxyl termini, two short membrane spanning segments, and a large extracellular loop with a conserved cysteine-rich region
- There are three homologous isoforms of the ENaC (alpha, beta, and gamma) protein
- ENaC in the kidney, lung, and colon plays an essential role in trans-epithelial sodium and fluid balance
- ENaC also mediates aldosterone-dependent sodium reabsorption in the distal nephron of the kidney, thus regulating blood pressure
- ENaC is thought to be regulated, in part, through association with the cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion channel
- Gain-of-function mutations in beta- or gamma-ENaC can cause severe arterial hypertension (Liddels syndrome) and loss-of-function mutations in alpha- or beta-ENaC causes pseudohypoaldosteronism (PHA-1)
- Diseases associated with SCN10A include Episodic Pain Syndrome, Familial, 2 and Sodium Channelopathy-Related Small Fiber Neuropathy.
Compare Similar Items
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Antigen: SCN10A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Scn10a
Gene Alias: FEPS2; hPN3; mPN3; Na(V)1.8; Nav1.8; peripheral nerve sodium channel 3; PN3; Scn10a; Sensory neuron sodium channel; SNS; Sodium channel protein type 10 subunit alpha; sodium channel protein type X subunit alpha; sodium channel type X alpha polypeptide; sodium channel voltage-gated type X alpha polypeptide; sodium channel, voltage gated, type X alpha subunit; sodium channel, voltage-gated, type 10, alpha polypeptide; sodium channel, voltage-gated, type X, alpha; sodium channel, voltage-gated, type X, alpha polypeptide; sodium channel, voltage-gated, type X, alpha subunit; sodium voltage-gated channel alpha subunit 10; voltage gated sodium channel; voltage-gated sodium channel subunit alpha Nav1.8
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20264, 29571, 6336
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q62968, Q6QIY3, Q9Y5Y9
Gene Symbols: Scn10a
Immunogen: A synthesized peptide derived from human SCN10A(Accession Q9Y5Y9), corresponding to amino acid residues R461-P481.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SCN10A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Scn10a
Gene Alias:
FEPS2; hPN3; mPN3; Na(V)1.8; Nav1.8; peripheral nerve sodium channel 3; PN3; Scn10a; Sensory neuron sodium channel; SNS; Sodium channel protein type 10 subunit alpha; sodium channel protein type X subunit alpha; sodium channel type X alpha polypeptide; sodium channel voltage-gated type X alpha polypeptide; sodium channel, voltage gated, type X alpha subunit; sodium channel, voltage-gated, type 10, alpha polypeptide; sodium channel, voltage-gated, type X, alpha; sodium channel, voltage-gated, type X, alpha polypeptide; sodium channel, voltage-gated, type X, alpha subunit; sodium voltage-gated channel alpha subunit 10; voltage gated sodium channel; voltage-gated sodium channel subunit alpha Nav1.8
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20264, 29571, 6336
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q62968, Q6QIY3, Q9Y5Y9
Gene Symbols:
Scn10a
Immunogen:
A synthesized peptide derived from human SCN10A(Accession Q9Y5Y9), corresponding to amino acid residues R461-P481.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CD56
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ncam1
Gene Alias: adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17967, 4684
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P13591, P13595
Gene Symbols: Ncam1
Immunogen: A synthesized peptide derived from human NCAM1(Accession P13591), corresponding to amino acid residues A778-E828.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
CD56
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ncam1
Gene Alias:
adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17967, 4684
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P13591, P13595
Gene Symbols:
Ncam1
Immunogen:
A synthesized peptide derived from human NCAM1(Accession P13591), corresponding to amino acid residues A778-E828.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: NCAPH
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NCAPH
Gene Alias: A730011O11Rik; barren homolog 1; barren homolog protein 1; Brrn; BRRN1; Caph; CAP-H; Chromosome-associated protein H; condensin complex subunit 2; HCAP-H; KIAA0074; mCAP-H; mKIAA0074; Ncaph; Non-SMC condensin I complex subunit H; non-SMC condensin I complex, subunit H; XCAP-H homolog
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23397
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q15003
Gene Symbols: NCAPH
Immunogen: A synthesized peptide derived from human NCAPH(Accession Q15003), corresponding to amino acid residues D443-L493.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NCAPH
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NCAPH
Gene Alias:
A730011O11Rik; barren homolog 1; barren homolog protein 1; Brrn; BRRN1; Caph; CAP-H; Chromosome-associated protein H; condensin complex subunit 2; HCAP-H; KIAA0074; mCAP-H; mKIAA0074; Ncaph; Non-SMC condensin I complex subunit H; non-SMC condensin I complex, subunit H; XCAP-H homolog
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23397
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q15003
Gene Symbols:
NCAPH
Immunogen:
A synthesized peptide derived from human NCAPH(Accession Q15003), corresponding to amino acid residues D443-L493.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NCBP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NCBP1
Gene Alias: 80 kDa nuclear cap-binding protein; AU014645; AW538051; CBP80; MGC2087; NCBP; NCBP 80 kDa subunit; Ncbp1; nuclear cap binding protein subunit 1; nuclear cap binding protein subunit 1, 80kD; nuclear cap binding protein subunit 1, 80kDa; nuclear cap-binding protein subunit 1; RP11-546O6.1; Sto1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 298075, 433702, 4686
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q09161, Q3UYV9, Q56A27
Gene Symbols: NCBP1
Immunogen: A synthesized peptide derived from human NCBP1(Accession Q09161), corresponding to amino acid residues M1-I35.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
NCBP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NCBP1
Gene Alias:
80 kDa nuclear cap-binding protein; AU014645; AW538051; CBP80; MGC2087; NCBP; NCBP 80 kDa subunit; Ncbp1; nuclear cap binding protein subunit 1; nuclear cap binding protein subunit 1, 80kD; nuclear cap binding protein subunit 1, 80kDa; nuclear cap-binding protein subunit 1; RP11-546O6.1; Sto1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
298075, 433702, 4686
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q09161, Q3UYV9, Q56A27
Gene Symbols:
NCBP1
Immunogen:
A synthesized peptide derived from human NCBP1(Accession Q09161), corresponding to amino acid residues M1-I35.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG