PIPA5115800

PROX1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5115800-Each-of-1 In Stock ₹ 44,705.10

PIPA5115800 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

PROX1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Prox1

Gene Alias

A230003G05Rik; homeobox prospero-like protein PROX1; prospero homeobox 1; prospero homeobox protein 1; prospero-related homeobox 1; Prox 1; PROX1; PROX-1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5629

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q92786

Gene Symbols

Prox1

Immunogen

A synthesized peptide derived from human PROX1(Accession Q92786), corresponding to amino acid residues T477-K527.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total PROX1
  • The expression pattern of the Prox1 homeo box gene suggests that it has a role in a variety of embryonic tissues, including lens
  • Analysis of mRNA reveals that Prox mRNA is present in many different human tissues and that lens demonstrated the highest level
  • Homozygous Prox1-null mice die at midgestation from multiple developmental defects, and a targeted effect on lens development has been reported
  • Prox1 inactivation caused abnormal cellular proliferation, downregulated expression of the cell cycle inhibitors Cdkn1b and Cdkn1c, misexpression of E-cadherin, and excessive apoptosis
  • Consequently, mutant lens cells failed to polarize and elongate properly, resulting in a hollow lens
  • The Prox1 gene is expressed in a subpopulation of endothelial cells that by budding and sprouting give rise to the lymphatic system
  • Prox1 appears to be a specific and required regulator of the development of the lymphatic system
  • Prox1 also has been document to be required for hepatocyte migration in the mouse
  • Loss of Prox1 results in a smaller liver with a reduced population of clustered hepatocytes
  • The homeodomain protein Prox1 regulates the egress of progenitor cells from the cell cycle in the embryonic mouse retina
  • Cells lacking Prox1 are less likely to stop dividing, and ectopic expression of Prox1 forces progenitor cells to exit the cell cycle
  • Prox1 acts as a key participant in progenitor-cell proliferation and cell-fate determination in the vertebrate retina.

Compare Similar Items

Show Difference

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PIPA5115800

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Antigen:
PROX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Prox1

Gene Alias:
A230003G05Rik; homeobox prospero-like protein PROX1; prospero homeobox 1; prospero homeobox protein 1; prospero-related homeobox 1; Prox 1; PROX1; PROX-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5629

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q92786

Gene Symbols:
Prox1

Immunogen:
A synthesized peptide derived from human PROX1(Accession Q92786), corresponding to amino acid residues T477-K527.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5115801

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Antigen:
PRRG4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRRG4

Gene Alias:
9930111I18Rik; hypothetical protein LOC550330; PRGP4; proline rich and Gla domain 4; proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane); proline rich Gla 4 (transmembrane) isoform 1; proline rich Gla 4 (transmembrane) isoform 2; proline rich Gla 4 (transmembrane) isoform 3; proline-rich gamma-carboxyglutamic acid protein 4; Proline-rich Gla protein 4; PRRG4; RGD1560542; TMG4; Transmembrane gamma-carboxyglutamic acid protein 4; zgc:110234

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
228413, 499847, 79056

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8BGN6, Q9BZD6

Gene Symbols:
PRRG4

Immunogen:
A synthesized peptide derived from human PRRG4(Accession Q9BZD6), corresponding to amino acid residues E81-F131.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5115803

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Antigen:
PSMA4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Psma4

Gene Alias:
C9; HC9; HsT17706; LOW QUALITY PROTEIN: proteasome subunit alpha type-4; macropain subunit C9; MGC111191; MGC12467; MGC24813; Multicatalytic endopeptidase complex subunit C9; multicatalytic proteinase subunit L; proteasome (prosome, macropain) subunit, alpha type 4; proteasome (prosome, macropain) subunit, alpha type, 4; proteasome 20S subunit alpha 4; proteasome alpha 4 subunit; proteasome component C9; proteasome subunit alpha 4; proteasome subunit alpha type-4; proteasome subunit alpha type-4-like protein; proteasome subunit HC9; proteasome subunit L; PSC9; PSMA 4; PSMA4; QtsA-10816; unnamed protein product; wu:fe05d10; zgc:56176

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26441, 29671, 5685

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P21670, P25789, Q9R1P0

Gene Symbols:
Psma4

Immunogen:
A synthesized peptide derived from human PSMA4(Accession P25789), corresponding to amino acid residues M1-L35.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5115807

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Antigen:
PU.1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPI1

Gene Alias:
31 kDa transforming protein; 31 kDa-transforming protein; 31kDa Transforming Protein; Dis1; Dis-1; hCG_25181; hematopoietic transcription factor PU.1; OF; Pu.1; SFFV proviral integration 1; SFFV proviral integration 1 protein; Sfpi1; Sfpi-1; Spi1; SPI-1; Spi-1 proto-oncogene; SPIA; SPI-A; spleen focus forming virus (SFFV) proviral integration oncogene; spleen focus forming virus (SFFV) proviral integration oncogene spi1; spleen focus forming virus proviral integration oncogene spi1; Tcfpu1; Tfpu.1; Transcription factor PU.1; Transcription Factor spi1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20375, 366126, 6688

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P17433, P17947, Q6BDS1

Gene Symbols:
SPI1

Immunogen:
A synthesized peptide derived from human SPI1(Accession P17947), corresponding to amino acid residues L124-Q174.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG