PIPA5115899

SIGLEC7 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5115899-Each-of-1 In Stock ₹ 44,705.10

PIPA5115899 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SIGLEC7

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SIGLEC7

Gene Alias

Adhesion inhibitory receptor molecule 1; adhesion inhibitory receptor molecule 1, siglec-7; AIRM1; AIRM-1; CD328; CDw328; D-siglec; p75; p75/ AIRM-1; p75/AIRM1; QA79; QA79 membrane protein; sialic acid binding Ig like lectin 7; sialic acid binding Ig-like lectin 7; sialic acid binding immunoglobulin-like lectin 7; sialic acid-binding Ig-like lectin 7; Siglec; SIGLEC19P; SIGLEC7; SIGLEC-7; SIGLECP2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

27036

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q9Y286

Gene Symbols

SIGLEC7

Immunogen

A synthesized peptide derived from human SIGLEC7(Accession Q9Y286), corresponding to amino acid residues L424-K467.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total Siglec 7
  • Putative adhesion molecule that mediates sialic-acid dependent binding to cells
  • Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid
  • Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide)
  • The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface
  • In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules
  • Mediates inhibition of natural killer cells cytotoxicity
  • May play a role in hemopoiesis
  • Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).

Compare Similar Items

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Thermo Scientific

PIPA5115899

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Antigen:
SIGLEC7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIGLEC7

Gene Alias:
Adhesion inhibitory receptor molecule 1; adhesion inhibitory receptor molecule 1, siglec-7; AIRM1; AIRM-1; CD328; CDw328; D-siglec; p75; p75/ AIRM-1; p75/AIRM1; QA79; QA79 membrane protein; sialic acid binding Ig like lectin 7; sialic acid binding Ig-like lectin 7; sialic acid binding immunoglobulin-like lectin 7; sialic acid-binding Ig-like lectin 7; Siglec; SIGLEC19P; SIGLEC7; SIGLEC-7; SIGLECP2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27036

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9Y286

Gene Symbols:
SIGLEC7

Immunogen:
A synthesized peptide derived from human SIGLEC7(Accession Q9Y286), corresponding to amino acid residues L424-K467.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA511590

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Antigen:
TLR2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tlr2

Gene Alias:
CD282; Ly105; TIL4; Tlr2; TLR-2; toll like receptor 2; toll/interleukin-1 receptor-like protein 4; Toll-like receptor; toll-like receptor 2; toll-like receptor 2 variant 1; toll-like receptor 2 variant 2; toll-like-receptor 2, exon 1a_; Toll-like-receptor, exon 1b; Toll-like-receptor, exon 1b_; Toll-like-receptor2, exon 1a

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status:
RUO

Gene ID (Entrez):
7097

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
__

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
O60603

Gene Symbols:
Tlr2

Immunogen:
KLH conjugated synthetic peptide between 212-242 amino acids from the N-terminal region of human TLR2

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115900

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Antigen:
SIGLEC9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIGLEC9

Gene Alias:
Cd170; CD329; CDw329; FOAP-9; LOC100062855; LOC719831; MIS; mSiglec-E; Myeloid inhibitory siglec; OBBP-LIKE; Protein FOAP-9; sialic acid binding Ig like lectin 9; sialic acid binding Ig-like lectin 5; sialic acid binding Ig-like lectin 9; sialic acid binding Ig-like lectin E; sialic acid-binding Ig-like lectin 12; Sialic acid-binding Ig-like lectin 5; sialic acid-binding Ig-like lectin 9; Sialic acid-binding Ig-like lectin E; sialic acid-binding Ig-like lectin-like 1; sialic acid-binding immunoglobulin-like lectin E; Siglec; Siglec12; siglec-12; Siglec5; Siglec-5; SIGLEC9; siglec-9; Siglece; Siglec-E; Siglecl1; siglec-L1; SIGLEC-like 1; UNQ668/PRO1302

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27180

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9Y336

Gene Symbols:
SIGLEC9

Immunogen:
A synthesized peptide derived from human SIGLEC9(Accession Q9Y336), corresponding to amino acid residues G383-Y433.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115901

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Antigen:
MAPKAP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPKAP1

Gene Alias:
AI591529; D230039K05Rik; im:7143088; JC310; MAPK associated protein 1; mapkap1; MEKK2-interacting protein 1; MGC2745; Mip1; MIP1SIN1SIN1b; mitogen activated protein kinase associated protein 1; mitogen-activated protein kinase 2-associated protein 1; mitogen-activated protein kinase associated protein 1; mSIN1; ras inhibitor MGC2745; RP11-269P11.1; SAPK interacting protein; SAPK-interacting protein 1; si:ch73-242f23.1; SIN1; SIN1b; SIN1g; stress-activated map kinase interacting protein 1; stress-activated map kinase-interacting protein 1; stress-activated protein kinase-interacting 1; target of rapamycin complex 2 subunit MAPKAP1; TORC2 subunit MAPKAP1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
227743, 296648, 79109

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q6AYF1, Q8BKH7, Q9BPZ7

Gene Symbols:
MAPKAP1

Immunogen:
A synthesized peptide derived from human MAPKAP1(Accession Q9BPZ7), corresponding to amino acid residues Y484-Q522.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG