PIPA5115920
SLFN11 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5115920-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5115920 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
SLFN11
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SLFN11
Gene Alias
schlafen family member 11; SLFN11; SLFN8/9
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
91607
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
Q7Z7L1
Gene Symbols
SLFN11
Immunogen
A synthesized peptide derived from human SLFN11(Accession Q7Z7L1), corresponding to amino acid residues I160-S210.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total SLFN11
- Inhibitor of DNA replication that promotes cell death in response to DNA damage (PubMed:22927417, PubMed:26658330, PubMed:29395061)
- Acts as a guardian of the genome by killing cells with defective replication (PubMed:29395061)
- Persistently blocks stressed replication forks by opening chromatin across replication initiation sites at stressed replication forks, possibly leading to unwind DNA ahead of the MCM helicase and block fork progression, μgtimately leading to cell death (PubMed:29395061)
- Acts independently of ATR (PubMed:29395061)
- Also acts as an interferon (IFN)-induced antiviral protein which acts as an inhibitor of retrovirus protein synthesis (PubMed:23000900)
- Specifically abrogates the production of retroviruses such as human immunodeficiency virus 1 (HIV-1) by acting as a specific inhibitor of the synthesis of retroviruses encoded proteins in a codon-usage-dependent manner (PubMed:23000900)
- Binds to tRNAs and exploits the unique viral codon bias towards A/T nucleotides (PubMed:23000900)
- The exact inhibition mechanism is unclear: may either sequester tRNAs, prevent their maturation via post-transcriptional processing or may accelerate their deacylation (PubMed:23000900)
- Does not inhibit reverse transcription, integration or production and nuclear export of viral RNA (PubMed:23000900)
- [UniProt]
Compare Similar Items
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Antigen: SLFN11
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SLFN11
Gene Alias: schlafen family member 11; SLFN11; SLFN8/9
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 91607
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q7Z7L1
Gene Symbols: SLFN11
Immunogen: A synthesized peptide derived from human SLFN11(Accession Q7Z7L1), corresponding to amino acid residues I160-S210.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SLFN11
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SLFN11
Gene Alias:
schlafen family member 11; SLFN11; SLFN8/9
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
91607
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q7Z7L1
Gene Symbols:
SLFN11
Immunogen:
A synthesized peptide derived from human SLFN11(Accession Q7Z7L1), corresponding to amino acid residues I160-S210.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SLFN14
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SLFN14
Gene Alias: BDPLT20; C-terminally truncated SLFN14 endoribonuclease; Gm20; LRRGT00163; Protein SLFN14; schlafen 14; schlafen family member 14; schlafen family member 14, pseudogene; SLFN14; Slfn14-ps
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 342618
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P0C7P3
Gene Symbols: SLFN14
Immunogen: A synthesized peptide derived from human SLFN14(Accession P0C7P3), corresponding to amino acid residues G731-G781.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SLFN14
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SLFN14
Gene Alias:
BDPLT20; C-terminally truncated SLFN14 endoribonuclease; Gm20; LRRGT00163; Protein SLFN14; schlafen 14; schlafen family member 14; schlafen family member 14, pseudogene; SLFN14; Slfn14-ps
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
342618
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P0C7P3
Gene Symbols:
SLFN14
Immunogen:
A synthesized peptide derived from human SLFN14(Accession P0C7P3), corresponding to amino acid residues G731-G781.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SLIT2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SLIT2
Gene Alias: downregulated during adipocyte differentiation-1; Drad-1; E030015M03Rik; E130320P19Rik; mKIAA4141; neurogenic extracellular slit protein; SLIL3; Slit; slit guidance ligand 2; slit homolog 2 (Drosophila); slit homolog 2 protein; Slit homolog 2 protein C-product; Slit homolog 2 protein N-product; SLIT2; Slit-2; Slit2 protein
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 360272, 9353
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: O94813, Q9WVC1
Gene Symbols: SLIT2
Immunogen: A synthesized peptide derived from human SLIT2(Accession O94813), corresponding to amino acid residues N465-T515.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SLIT2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SLIT2
Gene Alias:
downregulated during adipocyte differentiation-1; Drad-1; E030015M03Rik; E130320P19Rik; mKIAA4141; neurogenic extracellular slit protein; SLIL3; Slit; slit guidance ligand 2; slit homolog 2 (Drosophila); slit homolog 2 protein; Slit homolog 2 protein C-product; Slit homolog 2 protein N-product; SLIT2; Slit-2; Slit2 protein
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
360272, 9353
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O94813, Q9WVC1
Gene Symbols:
SLIT2
Immunogen:
A synthesized peptide derived from human SLIT2(Accession O94813), corresponding to amino acid residues N465-T515.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TAGLN
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TAGLN
Gene Alias: 22 kDa actin-binding protein; 25 kDa F-actin-binding protein; actin-associated protein p27; DKFZp686B01212; DKFZp686P11128; Protein WS3-10; similar to transgelin; Sm22; sm22 alpha; SM22A; Sm22alpha; SM22-alpha; SMCC; smooth muscle 22 protein; smooth muscle protein 22-alpha; TAGLN; TAGLN1; Transgelin; transgelin variant 2; Ws310; WS3-10
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 21345, 25123, 6876
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P31232, P37804, Q01995
Gene Symbols: TAGLN
Immunogen: A synthesized peptide derived from human TAGLN(Accession Q01995), corresponding to amino acid residues E170-S201.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TAGLN
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TAGLN
Gene Alias:
22 kDa actin-binding protein; 25 kDa F-actin-binding protein; actin-associated protein p27; DKFZp686B01212; DKFZp686P11128; Protein WS3-10; similar to transgelin; Sm22; sm22 alpha; SM22A; Sm22alpha; SM22-alpha; SMCC; smooth muscle 22 protein; smooth muscle protein 22-alpha; TAGLN; TAGLN1; Transgelin; transgelin variant 2; Ws310; WS3-10
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
21345, 25123, 6876
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P31232, P37804, Q01995
Gene Symbols:
TAGLN
Immunogen:
A synthesized peptide derived from human TAGLN(Accession Q01995), corresponding to amino acid residues E170-S201.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG