PIPA5116025

TET2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5116025-Each-of-1 In Stock ₹ 44,705.10

PIPA5116025 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

TET2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TET2

Gene Alias

Ayu17-449; E130014J05Rik; FLJ20032; KIAA1546; MDS; methylcytosine dioxygenase TET2; MGC125715; mKIAA1546; Nbla00191; OTTHUMP00000161869; probable methylcytosine dioxygenase TET2; Protein Ayu17 449; Protein Ayu17-449; RGD1311625; Tet 2; tet methylcytosine dioxygenase 2; tet oncogene 2; tet oncogene family member 2; TET2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

214133, 310859, 54790

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q4JK59, Q6N021

Gene Symbols

TET2

Immunogen

A synthesized peptide derived from human TET2(Accession Q6N021), corresponding to amino acid residues A1264-D1314.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total TET2
  • TET2 is a dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydromethylcytosine (5hmC) and plays a key role in active DNA demethylation
  • TET2 has a preference for 5-hydroxymethylcytosine in CpG motifs
  • It mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC) and conversion of 5fC to 5-carboyxlcytosine (5caC)
  • Conversion of 5mC into 5hmC, 5fC, and 5caC probably constitutes the first step in cytonsine demethylation
  • In addition to TET2’s role in DNA demethylation, it is also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT
  • Mutations in the genes can result in Polycythemia vera and Myelodysplastic syndrome.

Compare Similar Items

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Thermo Scientific

PIPA5116025

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Antigen:
TET2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TET2

Gene Alias:
Ayu17-449; E130014J05Rik; FLJ20032; KIAA1546; MDS; methylcytosine dioxygenase TET2; MGC125715; mKIAA1546; Nbla00191; OTTHUMP00000161869; probable methylcytosine dioxygenase TET2; Protein Ayu17 449; Protein Ayu17-449; RGD1311625; Tet 2; tet methylcytosine dioxygenase 2; tet oncogene 2; tet oncogene family member 2; TET2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
214133, 310859, 54790

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q4JK59, Q6N021

Gene Symbols:
TET2

Immunogen:
A synthesized peptide derived from human TET2(Accession Q6N021), corresponding to amino acid residues A1264-D1314.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5116027

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Antigen:
TEX14

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TEX14

Gene Alias:
C85585; cancer/testis antigen 113; CT113; Inactive serine/threonine-protein kinase TEX14; LOW QUALITY PROTEIN: inactive serine/threonine-protein kinase TEX14; protein kinase-like protein SgK307; SGK307; Sugen kinase 307; testis expressed 14; testis expressed 14, intercellular bridge forming factor; testis expressed gene 14; testis expressed sequence 14; testis-expressed protein 14; Testis-expressed sequence 14; Testis-expressed sequence 14 protein; Tex14; Unknown (protein for MGC:133568)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56155

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8IWB6

Gene Symbols:
TEX14

Immunogen:
A synthesized peptide derived from human TEX14(Accession Q8IWB6), corresponding to amino acid residues T873-R923.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5116029

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Antigen:
AP2 gamma

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TFAP2C

Gene Alias:
AA409384; activating enhancer binding protein 2 gamma; activating enhancer-binding protein 2 gamma; activator protein 2 gamma; AP-2.2; AP2gamma; AP2-GAMMA; ERF1; estrogen receptor factor 1; hAP-2g; stimulated by retinoic acid gene 2; Stra2; Tcfap2c; TFAP2C; TFAP2G; Transcription factor AP-2 gamma; transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma); transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma); transcription factor AP-2, gamma; transcription factor ERF-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21420, 7022

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q61312, Q92754

Gene Symbols:
TFAP2C

Immunogen:
A synthesized peptide derived from human TFAP2C(Accession Q92754), corresponding to amino acid residues V409-K450.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5116030

--


Antigen:
AP2 gamma

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TFAP2C

Gene Alias:
AA409384; activating enhancer binding protein 2 gamma; activating enhancer-binding protein 2 gamma; activator protein 2 gamma; AP-2.2; AP2gamma; AP2-GAMMA; ERF1; estrogen receptor factor 1; hAP-2g; stimulated by retinoic acid gene 2; Stra2; Tcfap2c; TFAP2C; TFAP2G; Transcription factor AP-2 gamma; transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma); transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma); transcription factor AP-2, gamma; transcription factor ERF-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
362280, 7022

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q92754

Gene Symbols:
TFAP2C

Immunogen:
A synthesized peptide derived from human TFAP2C(Accession Q92754), corresponding to amino acid residues V409-K450.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG