PIPA5116205
Histone H2A.X Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5116205-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5116205 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Histone H2A.X
Classification
Polyclonal
Conjugate
Unconjugated
Gene
H2AX
Gene Alias
AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2A.X; H2A.X variant histone; H2A/X; h2afx; H2ax; H2AX histone; Hist5-2ax; histone 5 protein 2ax; histone H2A.x; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3014
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.25 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P16104
Gene Symbols
H2AX
Immunogen
KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human H2AFX
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description Histone H2A.X (H2AX) is a member of the histone H2A family which is one of the four core histones making up the nucleosome core particle
- In eukaryotes, DNA double strand breaks (DSBs) have been shown to trigger the phosphorylation of serine 139 at the carboxy terminus of histone H2AX resulting in gamma-H2AX
- The phosphorylation of H2AX can be detected by Western blotting or immunofluorescence, revealing the frequency of DSBs
- The phosphatidylinositol 3-kinases have been implicated in H2AX phosphorylation, but it is unclear if ATM is the primary H2AX kinase or if other members of the family such as DNA-PK and ATR contribute in a similar manner
- Structurally, H2A.x contains 143 amino acid residues
- Histone H2A.X is considered a basal histone, being synthesized in G1 as well as in S-phase, and its mRNA contains polyA addition motifs and a polyA tail along with the conserved stem-loop and U7 binding sequences involved in the processing and stability of replication type histone mRNAs
- There are two forms of Histone H2A.X mRNA, one about 1600 bases long and contains polyA; the other about 575 bases long, lacking polyA
- The short form behaves as a replication type histone mRNA, while the longer behaves as a basal type histone mRNA
- Histone H2A.X maps to the 11q23.2-q23.3 region of the human chromosome
- Histone H2A.x contributes to histone-formation and therefore the structure of DNA
- Histone H2A variant H2A.x specifically regulates the interaction of MDC1 (mediator of DNA damage checkpoint protein 1), a DNA repair protein to the sites of DNA damage.
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Antigen: Histone H2A.X
Classification: Polyclonal
Conjugate: Unconjugated
Gene: H2AX
Gene Alias: AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2A.X; H2A.X variant histone; H2A/X; h2afx; H2ax; H2AX histone; Hist5-2ax; histone 5 protein 2ax; histone H2A.x; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3014
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.25 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P16104
Gene Symbols: H2AX
Immunogen: KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human H2AFX
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Histone H2A.X
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
H2AX
Gene Alias:
AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2A.X; H2A.X variant histone; H2A/X; h2afx; H2ax; H2AX histone; Hist5-2ax; histone 5 protein 2ax; histone H2A.x; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3014
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.25 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P16104
Gene Symbols:
H2AX
Immunogen:
KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human H2AFX
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: KIR2D
Classification: Polyclonal
Conjugate: Unconjugated
Gene: KIR2DS5
Gene Alias: 183ActI; CD158; CD158 antigen-like family member A; CD158 antigen-like family member G; CD158 antigen-like family member H; CD158 antigen-like family member I; CD158 antigen-like family member J; CD158A; CD158b; CD158B1; CD158G; CD158H; CD158I; CD158j; cl-49; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 5; killer cell immunoglobulin-like receptor 2DL1; Killer cell immunoglobulin-like receptor 2DS1; killer cell immunoglobulin-like receptor 2DS2; Killer cell immunoglobulin-like receptor 2DS4; killer cell immunoglobulin-like receptor 2DS5; killer cell immunoglobulin-like receptor KIR2DS2; killer cell immunoglo
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 100132285, 3802, 3806, 3809, 3810
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P43626, P43631, P43632, Q14953, Q14954
Gene Symbols: KIR2DL1, KIR2DS1, KIR2DS2, KIR2DS4, KIR2DS5
Immunogen: KLH conjugated synthetic peptide between 151-180 amino acids from the Central region of human KIR2DS1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
KIR2D
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
KIR2DS5
Gene Alias:
183ActI; CD158; CD158 antigen-like family member A; CD158 antigen-like family member G; CD158 antigen-like family member H; CD158 antigen-like family member I; CD158 antigen-like family member J; CD158A; CD158b; CD158B1; CD158G; CD158H; CD158I; CD158j; cl-49; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 5; killer cell immunoglobulin-like receptor 2DL1; Killer cell immunoglobulin-like receptor 2DS1; killer cell immunoglobulin-like receptor 2DS2; Killer cell immunoglobulin-like receptor 2DS4; killer cell immunoglobulin-like receptor 2DS5; killer cell immunoglobulin-like receptor KIR2DS2; killer cell immunoglo
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
100132285, 3802, 3806, 3809, 3810
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
__
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P43626, P43631, P43632, Q14953, Q14954
Gene Symbols:
KIR2DL1, KIR2DS1, KIR2DS2, KIR2DS4, KIR2DS5
Immunogen:
KLH conjugated synthetic peptide between 151-180 amino acids from the Central region of human KIR2DS1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ZNF154
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ZNF154
Gene Alias: KIAA2003; pHZ-92; Zinc finger protein 154; ZNF154
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 7710
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q13106
Gene Symbols: ZNF154
Immunogen: KLH conjugated synthetic peptide between 40-68 amino acids from the N-terminal region of human ZNF154
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ZNF154
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ZNF154
Gene Alias:
KIAA2003; pHZ-92; Zinc finger protein 154; ZNF154
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
7710
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
__
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q13106
Gene Symbols:
ZNF154
Immunogen:
KLH conjugated synthetic peptide between 40-68 amino acids from the N-terminal region of human ZNF154
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: FAM198B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FAM198B
Gene Alias: 1110032E23Rik; 2210419I08Rik; AD021; AD036; AV011458; C4orf18; Ened; Expressed in nerve and epithelium during development; FAM198B; family with sequence similarity 198 member B; family with sequence similarity 198, member B; gask1b; GaskbB; golgi associated kinase 1B; Golgi-associated kinase 1B; LOW QUALITY PROTEIN: protein FAM198B; protein ENED; protein ENED; protein FAM198B; protein FAM198B; UNQ2512/PRO6001
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 51313
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q6UWH4
Gene Symbols: FAM198B
Immunogen: KLH conjugated synthetic peptide between 275-304 amino acids from the Central region of human C4orf18
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
FAM198B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FAM198B
Gene Alias:
1110032E23Rik; 2210419I08Rik; AD021; AD036; AV011458; C4orf18; Ened; Expressed in nerve and epithelium during development; FAM198B; family with sequence similarity 198 member B; family with sequence similarity 198, member B; gask1b; GaskbB; golgi associated kinase 1B; Golgi-associated kinase 1B; LOW QUALITY PROTEIN: protein FAM198B; protein ENED; protein ENED; protein FAM198B; protein FAM198B; UNQ2512/PRO6001
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
51313
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q6UWH4
Gene Symbols:
FAM198B
Immunogen:
KLH conjugated synthetic peptide between 275-304 amino acids from the Central region of human C4orf18
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG